Clinical trials: Knee Osteoarthritis
Osteoarthritis
Effectiveness of Aquatic Physical Therapy for Knee Osteoarthritis Patients
The purpose of this study is to determine whether education or aquatic physical therapy are effective in the treatment of osteoarthritis in Knee due to intensity of pain, function capacity, quality of life and kinetic.
- Trial name
- RCT-OA (NCT02247882)
- Testing
- Patient Education, Aquatic Physical Therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Estadual de Londrina
Osteoarthritis
Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients
The Collaborative Lifestyle Intervention Program in Knee OsteoArthritis Patients (CLIP-OA) compares a novel community-based exercise and dietary weight loss program to the Arthritis Foundation's Walk with Ease intervention on…
- Trial name
- CLIP-OA (NCT02835326)
- Testing
- Exercise and Dietary Weight Loss, Walk with Ease
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Osteoarthritis, Knee
Medial Unicondylar Knee Arthroplasty vs Total Knee Arthroplasty
In treatment of isolated medial unicondylar osteoarthritis of the knee (MU-OA), it is possible to choose between surgery with a unicondylar knee arthroplasty (UKA), or a total knee arthroplasty (TKA).
- Trial name
- UKAvsTKA (NCT03396640)
- Testing
- Unicondylar Knee Arthroplasty, Total Knee Arthroplasty
- Where
- 11 sites in Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Tibial Femoral Knee Osteoarthritis, Osteoarthritis
The Effect of Transcutaneous Electrical Nerve Stimulation on Quadriceps Central Activation and Gait
Participants diagnosed with tibial femoral knee osteoarthritis will be assigned to one of three treatment groups including: active transcutaneous electrical nerve stimulation (TENS), placebo TENS, and a control group.
- Trial name
- NCT00976079
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Virginia
Osteoarthritis of the Knee
Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee
this is a randomized double blinded trial which is conducted to measure the efficacy of topical virgin olive oil on osteoarthritis of knee that will be done in contrast to standard piroxicam gel.
- Trial name
- NCT00670475
- Testing
- Piroxicam, Olive Oil
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Ardabil University of Medical Sciences
Osteoarthritis
Imaging Biomarkers of Knee Osteoarthritis
This study aims to develop, evaluate and translate highly accelerated imaging sequences (each protocol under 5 minutes) for in-vivo knee Osteoarthritis applications on a standard clinical 3T scanner using novel compression…
- Trial name
- NCT02888119
- Testing
- PRISMA 3T MRI scanner (Siemens Medical Solutions)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Knee Osteoarthritis, Total Knee Arthroplasty
Adherence to Home-Based Physiotherapy and Music-Assisted Relaxation After Total Knee Arthroplasty
This randomized controlled study evaluated adherence to two home-based programs after total knee arthroplasty. All participants received a structured home-based physiotherapy program for 6 weeks.
- Trial name
- NCT07705971
- Testing
- Home-Based Physiotherapy, Music-Assisted Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Pamukkale University
Knee Osteoarthritis
Remote Tai Chi for Knee Osteoarthritis
The goal of this pragmatic randomized trial is to evaluate the effectiveness of remote Tai Chi to treat knee pain in adults with knee osteoarthritis.
- Trial name
- TAICHIKNEE (NCT06384898)
- Testing
- Remote Tai Chi
- Where
- United States
- Volunteers
- 480 people
- Sponsor
- Tufts Medical Center
Knee Osteoarthritis, Widespread Chronic Pain
Prevalence and Characteristics of Widespread Pain in People With Knee Osteoarthritis
The goal is to evaluate whether the number of pain sites or pain estimation with Instant and Constant Osteoarthritis Pain (ICOAP) is related to functional impairment in the lower extremity in people with knee osteoarthritis…
- Trial name
- NCT06854237
- Where
- Sweden
- Volunteers
- 114 people
- Sponsor
- Vastra Gotaland Region
Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery, Osteoarthritis (OA) of the Knee
Does the Use of Patient Specific Instrumentation Improve Outcomes in Knee Arthroplasty Surgery for Osteoarthritis When Compared to Standard Posterior Referenced Instrumentation?
The goal of this randomized study is to see if using patient-specific instruments (PSI) during total knee replacement surgery improves outcomes compared to standard instruments.
- Trial name
- PRIPSI (NCT06720012)
- Testing
- Patient specific instrumentation (PSI), Conventional instruments, Cemented Total Knee Arthroplasty
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Vastra Gotaland Region
Osteo Arthritis Knee
Prospective Observational Study of Pain Evolution in Patients With Primary Knee Osteoarthritis Treated With Pronolis® HD
Prospective observational study of 6 months of follow-up, of national and multicenter scope with medical device with CE marking and according to the usual clinical practice.
- Trial name
- NO-DOLOR (NCT04196764)
- Where
- Spain
- Volunteers
- 188 people
- Sponsor
- Procare Health Iberia S.L.
Knee Osteoarthritis
The Relation Between Abdominal Obesity, Type 2 Diabetes Mellitus and Knee Osteoarthritis
Background:Knee osteoarthritis is more common in patients with type-2 diabetes mellitus, however it is not known whether this effect is caused by diabetes itself or concominant abdominal obesity.
- Trial name
- NCT04779164
- Testing
- knee ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Eskisehir City Hospital
Obesity, Osteoarthritis
Reducing Obesity and Cartilage Compression in Knees
OA is a degenerative joint disease that involves the degradation of articular cartilage and underlying subchondral bone. Obesity is identified as a critical and potentially modifiable risk factor for the development and…
- Conditions
- Obesity, Osteoarthritis, Knee Osteoarthritis
- Trial name
- ROCCK (NCT04730557)
- Testing
- Weight Loss
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Duke University
Osteoarthritis
Cost Efficacy of a Clinical Pathway to Patients Undergoing Hip and Knee Replacement Surgery
In this randomised study a proactive care and rehabilitation intervention is compared to the current care and rehabilitation in patients undergoing primary hip and knee replacement surgery.
- Trial name
- NCT00175201
- Testing
- Proactive care and rehabilitation
- Where
- Denmark
- Volunteers
- 247 people
- Sponsor
- University of Aarhus
Anxiety, Pain
The Effect of Aromatherapy on Anxiety in Patients
Preoperative anxiety is considered a potential and preventable risk factor for postoperative complications.
- Trial name
- NCT05500664
- Testing
- Lavender Oil
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Knee Osteoarthritis
Assessment of the Efficacy of Andrographis Paniculata in Subjects With Mild to Moderate Osteoarthritis
This is a 12 weeks randomized, double-blind, placebo-controlled clinical study to assess the effect of Andrographis Paniculata at low dose of 300 mg/day and high dose of 600 mg/day in the study population in the age range of…
- Trial name
- A Paniculata (NCT03262792)
- Testing
- Andrographis Paniculata
- Where
- 4 sites in India
- Volunteers
- 108 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Osteoarthritis
The Efficacy and Safety of Invossa K Injection in Patients Diagnosed With Knee Osteoarthritis
The purpose of this study is to evaluate the efficacy and safety of intraarticular Invossa K Injection patients diagnosed with Kellgren \& Lawrence grade 2 knee osteoarthritis.
- Trial name
- NCT03383471
- Testing
- Invossa K Inj.
- Where
- 17 sites in South Korea
- Volunteers
- 146 people
- Sponsor
- Kolon Life Science
Osteoarthritis, Post Traumatic Degenerative Disease
Post-Market Study of the EPIK Knee System
The purpose of this study is to determine the short-term (2 yr) and midterm (5 yr) cumulative revision rates of the EPIK™ Uni-compartmental Knee System.
- Trial name
- EPIK (NCT01464632)
- Testing
- EPIK™ uni-compartmental knee
- Where
- United States
- Sponsor
- Encore Medical, L.P.
Osteoarthritis, Contracture
Reducing Recurrent Knee Flexion Contracture by Correcting Leg Length Discrepancy After Total Knee Arthroplasty for OA
Moving one's joints through their full range of motion (ROM) is crucial for health and wellbeing. Those who are unable to do so have difficulty carrying out simple activities like walking or feeding themselves.
- Trial name
- NCT02861521
- Testing
- Shoe lift
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Ottawa Hospital Research Institute
Arthritis, Osteo Arthritis Knee
Osteoarthritis Care Tools for Primary Care Providers
The purpose of this pilot study is to test OACareTools+, an intervention for healthcare providers that combines education, patient resources and support from a national organization, to help them make referrals of patients with…
- Trial name
- OACareTools (NCT06988163)
- Testing
- OACareTools+
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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