Clinical trials: Knee Osteoarthrosis
Knee Osteoarthritis
Balneotherapy With Acquabios Thermal Water in Knee Osteoarthritis
The aim of the study is the evaluation of the effect of balneotherapy with Acquabios bicarbonate-alkaline-sodium thermal water in ameliorating some signs and symptoms of knee osteoarthritis in human subjects suffering from this…
- Trial name
- NCT05352477
- Testing
- Balneotherapy with thermal water, Balneotherapy with tap water
- Volunteers
- 88 people
- Sponsor
- University of Roma La Sapienza
Knee Osteoarthritis, Knee Arthritis
Chitosan Versus Glucosamine Phonophoresis in the Management of Knee Osteoarthritis
The study will be conducted to answer the following questions: Is there an effect of phonophoresis using glucosamine on pain level , function and range of motion in knee osteoarthritis patients ? Is there an effect of…
- Trial name
- NCT05420441
- Testing
- Phonophoresis with chitosan, Phonophoresis with glucoasmine, Conventional Physical Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Knee Osteoarthritis
Changes in Physical Inactivity in Patients with Knee Osteoarthritis
This is an objective cohort study using objective recording of physical activity (accelerometry) during and after the GLAiD intervention to investigate if a sedentary behavior change by participating in an 6-week…
- Trial name
- NCT03125954
- Testing
- standardized exercise treatment for knee OA in Denmark (GLAiD)
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- Frederiksberg University Hospital
Osteoarthritis, Knee
Efficacy and Mechanism of FSN Treatment for Senile Knee Osteoarthritis
The goal of this clinical trial is to compare FSN with oral Nonsteroidal Antiinflammatory Drugs (NSAIDs) in pain relief and improvement in knee function among elder people, the main questions it aims to answer are: Q1: Compared…
- Trial name
- NCT06328153
- Testing
- Fu's Subcutaneous Needling, Celecoxib
- Volunteers
- 60 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Knee Osteoarthritis
Validity And Reliability Of The Short Physical Performance Battery In Patients Undergoing Total Knee Arthroplasty
Objectives: Practical, applicable, valid, and reliable tools are needed to assess physical performance in patients with Total Knee Arthroplasty(TKA) in a variety of settings, including routine clinical assessment, research…
- Trial name
- NCT06201637
- Testing
- Performance Test
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Dokuz Eylul University
Osteo Arthritis Knee, Osteoarthritis
The Impact of Genicular Nerves Chemical Neurolysis on the Quality of Life of Patients with Advanced Knee Osteoarthritis.
Genicular nerves chemical neurolysis in advanced osteoarthritis of the knee joint.
- Trial name
- NCT06087601
- Testing
- 0.9% Sodium chloride, 95% ethanol
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis, Knee, Hypertrophy
Comparison Among the Effects of Blood Flow Restriction Training and Conventional Exercise in Knee Osteoarthritis.
The main objective of the study is to compare the effects of Blood flow Restriction training vs. traditional exercises on knee pain , knee functional disability and on quadriceps strength in patient with knee osteoarthritis.
- Trial name
- NCT05058794
- Testing
- Blood flow Restriction/Resistance Training, Conventional Therapy Group
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Comparison of INIT and Dry Needling on Trigger Points in Knee OA
The purpose of the study is to compare the effects of Integrated Neuromuscular Inhibition Technique and Dry Needling on Functional Disability, Pain and Range of Motion.
- Trial name
- NCT06437730
- Testing
- Integrated Neuromuscular Inhibition Technique:, Dry needling:
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Osteoarthritis,Knee
The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty
Post-operative bleeding in total knee arthroplasty (TKA) can result in hypovolemic shock and unnecessity for allogenic blood transfusions.
- Trial name
- NCT03074994
- Testing
- Peri-articular TXA (15 mg/kg), Intraarticular TXA 2 g (40 mL), TXA combined with multimodal local anesthetic infiltration inject into peri-articular area
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Thammasat University
Knee Osteoarthritis, Anesthesia, Local
Liposomal Bupivacaine in Total Knee Arthroplasty
Pain management after total knee arthroplasty is essential for optimized clinical outcomes and higher satisfaction. Exparel (Pacira Pharmaceuticals, Parsippany, New Jersey, USA) is a long-acting Bupivacaine extended release…
- Trial name
- NCT03541265
- Testing
- Exparel, Adductor block protocol, peri-articular injection protocol
- Volunteers
- 70 people
- Sponsor
- Bronx-Lebanon Hospital Center Health Care System
Platelet Rich Plasma Injection, Ultrasonography
The Effects of Intra-articular and Peri-articular Platelet-rich Plasma (PRP) Injections ın Chronic Knee Osteoarthritis
The primary objective of this study is to evaluate and compare the effectiveness of ultrasound-guided combined intra-articular and peri-articular platelet-rich plasma (PRP) injections with intra-articular PRP injections alone in…
- Conditions
- Platelet Rich Plasma Injection, Ultrasonography, Gonarthrosis
- Trial name
- NCT07339137
- Testing
- Conservative Therapy, Intra-Articular PRP, Peri-Articular PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis, Rheumatoid Arthritis
A Prospective Munti-center Study on VANGUARD™ PS Total Knee Replacement System
The primary objectives of this pilot clinical study include: Evaluate clinical outcomes and quality of life on patients who received Vanguard PS Total Knee in Korean population Evaluate safety of Vanguard PS Total Knee in Korean…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Posttraumatic Deformity
- Trial name
- NCT01906177
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Knee Osteoarthritis, Joint Pain
Femoral Rotation and Patellar Positioning After TKA
Analysis of patellar positioning in the trochlear groove after TKA with and without the use of dynamic tensioner.
- Conditions
- Knee Osteoarthritis, Joint Pain, Joint Instability, Patella Disorder
- Trial name
- NCT05871112
- Testing
- Use of dynamic tensioner
- Where
- Poland
- Volunteers
- 125 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis
Functional Exploration of Cartilage in Patients With Osteoarthritis of the Knee Through MRI Sodium ( 23Na )
Osteoarthritis is a degenerative disease of hyaline cartilage not associated with an infection or an inflammatory process that affects millions of people.
- Trial name
- NCT02885402
- Testing
- MRI Sodium ( 23Na )
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Osteoarthritis
A Roentgen Stereophotogrammetric Analysis on Migration of Knee Prostheses.
The purpose of this study is to compare the early migration of two uncemented total knee arthroplasties with different metal coating. Only the tibial prosthesis plateau varies.
- Trial name
- Ti-Tan (NCT00138853)
- Testing
- Tibial component
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Knee Osteoarthritis
The Effectiveness of Virtual Reality Based Rehabilitation in Patients With Knee Osteoarthritis
We aimed to investigate the effects of virtual reality based rehabilitation program on patients with knee osteoarthritis.
- Trial name
- NCT04011553
- Testing
- Virtual Reality based Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Knee Osteoarthritis
Resistance Training in Knee Osteoarthritis
The purpose of this study is to determine whether: 1. Progressive resistance training improves pain and disability 2. Progressive Resistance training improves muscular strength, ability to walk and quality of life
- Trial name
- NCT01099371
- Testing
- exercise
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of São Paulo
Osteoarthritis
To Compare Anterior Knee Pain Between Non Severe and Severe Patellofemoral Arthritis After Oxford UKA
The aims of this study is to compare the results between patients without severe patellofemoral arthritis and patients with severe patellofemoral arthritis after mobile bearing UKA.
- Trial name
- NCT02557763
- Testing
- Oxford unicompartmental knee arthroplasty
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Knee Osteoarthritis (Knee OA)
Phase II/III Randomized Trial of UC-MSC Secretome vs Sodium Hyaluronate in Knee Osteoarthritis
This study is a randomized, double-blind, multicenter Phase II/III clinical trial designed to evaluate the effectiveness and safety of umbilical cord-derived mesenchymal stem cell (UC-MSC) secretome compared with sodium…
- Trial name
- SECRET-OA (NCT07337863)
- Testing
- UC-MSC-Derived Secretome, Sodium Hyaluronate (Hyalein)
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Sriwijaya
Knee Osteoarthritis, Joint Diseases
Feasibility of a Wearable-enabled Intervention for Promoting Physical Activity in People Knee OA
Physical activity is an essential first-line treatment for patients with knee osteoarthritis (OA). However, a 2013 systematic review found only 13% met the activity recommendation of 150 minutes or more per week.
- Trial name
- TRACK-OA (NCT02313506)
- Testing
- Education session, Fitbit Flex, and remote coaching by a PT, Same intervention with a 1 month delay
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of British Columbia
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