Clinical trials: Knee Osteoarthrosis
Osteo Arthritis Knee
Safety and Efficacy of JointAlive™ on the Knee-joint Function in Adults With Knee Arthritis
Osteoarthritis (OA) is a joint disorder caused by wear and tear on the joint over time; as a result, the protective cartilage of the bone in the joint gradually wears down.
- Trial name
- NCT04395547
- Testing
- JointAlive™
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Chenland Nutritionals Inc.
Ischemic Preconditioning
Effects of Ischemic Preconditioning on Conditioned Pain Modulation and Heart Rate Variability in Knee Osteoarthritis
Introduction: Musculoskeletal disorders have affected approximately 1.3 billion people worldwide. Evidence shows that chronic diseases and musculoskeletal conditions often occur together, and among them it is estimated that more…
- Trial name
- NCT05059652
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Paulista University
Obesity
Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis
This study will look at participants body weight from the start to the end of the study. It will also look at how much pain participants have in participants knee from the start to the end of the study and how this affects…
- Trial name
- NCT05064735
- Testing
- semaglutide 2.4 mg
- Where
- 122 sites in United States, Canada and 9 more
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Osteoarthritis, Knee
An Exploratory Clinical Study to Investigate the Effect of autoSTEM-OA and alloSTEM-OA in Participants With Knee Osteoarthritis
A phase 1 exploratory clinical study to investigate safety, tolerance and efficacy of a single intra-articular injection of autoSTEM-OA or alloSTEM-OA in participants with mild to moderate knee osteoarthritis
- Trial name
- NCT05789719
- Testing
- STEM-OA
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- StemMedical A/S
Osteoarthritis of the Knee
Cabbage Leaf Wraps in Osteoarthritis of the Knee
This randomised controlled trial aims to investigate the efficacy of cabbage leaf cataplasms in the treatment of primary symptomatic osteoarthritis of the knee.
- Trial name
- KoGon (NCT02027792)
- Testing
- Cabbage leave wraps, Diclofenac Gel
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Universität Duisburg-Essen
Knee Osteoarthritis
A Study of NCR100 Injection for the Treatment of Knee Osteoarthritis（ KOA）
This clinical study is to investigate the safety and efficacy of NCR100 injection in subjects with knee osteoarthritis (KOA). It contains two parts dose-escalating, and blind random study in adult KOA subjects.
- Trial name
- NCT06741098
- Testing
- NCR100, 0.9% Normal saline
- Volunteers
- 162 people
- Sponsor
- Nuwacell Biotechnologies Co., Ltd.
Osteoarthritis, Arthritis, Degenerative
Understanding the Differences in the Management of Patients With Arthritis of the Knee or Hip
The purpose of this study is to examine cultural and clinical context factors in African-American and white veterans with knee or hip osteoarthritis with a focus on how these factors may be potentially modifiable determinants of…
- Conditions
- Osteoarthritis, Arthritis, Degenerative, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT00105677
- Where
- United States
- Volunteers
- 980 people
- Sponsor
- US Department of Veterans Affairs
Osteoarthritis, Knee
Safety and Efficacy of Viscosupplementation of Hyaluronic Acid With Addition of Lecithin in Patients With Mild or Moderate Osteoarthrosis of the Knee Joint.
The main objective of this prospective, open-label clinical trial is to assess the effectiveness and safety of intra-articular liposomal gel therapy for knee OA symptoms.
- Trial name
- NCT06433492
- Testing
- Intra-articular injection
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Biovico Sp. z o.o.
Knee Osteoarthritis, Knee Rheumatism
Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?
One common anesthetic that is performed for total knee replacement surgery is spinal anesthesia with an adductor canal regional block, which involves injecting numbing medication in the thigh region for pain control after…
- Trial name
- NCT03326999
- Testing
- Obturator nerve regional block, Adductor canal regional block, Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Pain, Fibromyalgia
Chronic Pain, Couples, & Physical Activity
Chronic pain affects more than 50 million adults in the United States and is estimated to cost the nation more than $560 billion dollars each year.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04077164
- Testing
- No intervention, observational only.
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Illinois Institute of Technology
Osteo Arthritis Knee, Pain
Use of a Self-Guided Mindfulness Mobile Application to Improve Pain Outcomes in Individuals With Knee Osteoarthritis
This study will investigate if mindfulness training via a smartphone mobile app is effective in improving OA-related knee pain.
- Trial name
- NCT03936088
- Testing
- Intervention -- "Headspace" mindfulness application, Control -- "My Water Balance" application
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- jilliansylvester
Osteoarthritis
A Clinical Investigation of the Oxford® Partial Knee System
The purpose of this prospective data collection is to document the performance and clinical outcomes of the Oxford® Partial Knee System.
- Trial name
- NCT00699257
- Volunteers
- 85 people
- Sponsor
- Biomet Orthopedics, LLC
Knee Osteoarthritis
The Post-operative Effect of Applying Drainage on Total Knee Arthroplasty
This multicenter clinical trial aims to investigate the exact effect of drainage use for osteoarthritis patients in total knee arthroplasty (TKA) on post-operative performance.
- Trial name
- NCT03365271
- Testing
- drainage, non-drainage
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Knee Osteoarthristis
Effects of Intermittent Versus Continuous Blood Flow Restriction Training on Pain, Functional Ability, Muscle Strength and Exercise Perception Among Female Patients With Grade II Knee Osteoarthritis
This study holds significant clinical, academic, and practical importance in the field of musculoskeletal rehabilitation. Clinically, it addresses a critical need to identify an effective and tolerable strengthening strategy for…
- Trial name
- NCT07722975
- Testing
- Intermittent blood flow training (iBFR), Continuous blood flow training (cBFR)
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Lahore University of Biological and Applied Sciences
ACL Injury, Knee Osteoarthritis
The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.
The anterior cruciate ligament (ACL) is the main stabilizer of the knee joint, as it controls anteroposterior and rotatory knee laxity.
- Conditions
- ACL Injury, Knee Osteoarthritis, Knee Injuries
- Trial name
- NCT06442319
- Testing
- Platelet-rich plasma
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz
Knee Osteoarthritis
Race and Preference for Knee Replacement: A Patient-Centered Intervention
A randomized, controlled design will be utilized to examine and compare the effectiveness of the proposed educational intervention, which includes a combination of an educational decision aid and motivational interviewing with…
- Trial name
- REPAIR (NCT02413411)
- Testing
- DA/MI Intervention, an educational program (an NIH-developed booklet)
- Where
- United States
- Volunteers
- 493 people
- Sponsor
- University of Pennsylvania
Osteoarthritis, Knee
VItamin D Effect on Osteoarthritis Study
Observational evidence suggests that vitamin D deficiency may have a role in the causes of osteoarthritis (OA) and there are biologically plausible mechanisms to explain this.
- Trial name
- VIDEO (NCT01176344)
- Testing
- Vitamin D
- Where
- 2 sites in Australia
- Volunteers
- 413 people
- Sponsor
- Menzies Institute for Medical Research
Knee Pathology, Osteoarthritis, Knee
Knee Registry (Knieregister)
Rationale: In view of patient care, patient characteristics and treatment parameters are registered for all patients visiting the Mobility Clinic of the University Medical Center Utrecht for orthopaedic knee treatment.
- Conditions
- Knee Pathology, Osteoarthritis, Knee, Osteochondritis Dissecans, Chondral Defect
- Trial name
- NCT04364334
- Where
- Netherlands
- Volunteers
- 1,000,000 people
- Sponsor
- UMC Utrecht
Osteoarthritis of Knee
A Study to Evaluate the Safety and Efficacy of Humia Inj. in Patients With Symptomatic Osteoarthritis of the Knee
A Multi-Centre, Parallel, Double-Blind, Active comparator, Randomised phase III Clinical Trial
- Trial name
- NCT02893098
- Testing
- Humia inj., High hyal Plus inj.
- Where
- South Korea
- Volunteers
- 232 people
- Sponsor
- Huons Co., Ltd.
Osteoarthritis in the Knee
Effects of Therapeutic Touch on Osteoarthritis of the Knee
This study is to evaluate the efficacy of the Kreiger/Kunz method of Therapeutic Touch on function, pain perception and quality of life in persons with Osteoarthritis in the knee.
- Trial name
- NCT00759512
- Testing
- Therapeutic Touch
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Toledo Health Science Campus
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.