Clinical trials: Knee Osteoarthrosis
Osteo Arthritis Knee
Long-Duration Ultrasound for Knee Osteoarthritis
This study will measure the 24-week pain relief from long-duration ultrasound on the symptoms of knee arthritis pain.
- Trial name
- NCT03800927
- Testing
- Long duration ultrasound
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Osteoarthritis, Knee Arthroplasty
Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty
Patients undergoing primary total knee replacement will receive either motor sparing knee block to be performed by anesthesia or periarticular local anesthetic infiltration at the end of surgery by surgeons to assess pain relief…
- Conditions
- Osteoarthritis, Knee Arthroplasty, Pain Management
- Trial name
- NCT02540070
- Testing
- Periarticular, Motor free, Motor free with dex
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Osteoarthritis
Platelet Rich Plasma (PRP) Injections For Knee Osteoarthritis
It was conducted a prospective study with a series of 153 patients treated with PRP injections in patient affected by knee osteoarthritis.
- Trial name
- NCT04852380
- Testing
- PRP injections
- Where
- Italy
- Volunteers
- 153 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Pain, Osteoarthritis, Knee
Transdermal Ketoprofen to Treat Mild to Moderate Osteoarthritis (OA) Pain of the Knee
The purpose of the study is to evaluate the safety and effectiveness of the investigational ketoprofen patch with a controlled heating patch, compared to placebo (inactive substance) for the treatment of pain caused by…
- Trial name
- NCT00108810
- Testing
- Transdermal Ketoprofen Patch with CHADD
- Where
- 5 sites in United States
- Volunteers
- 118 people
- Sponsor
- ZARS Pharma Inc.
Osteoarthritis, Arthritis
Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): 10 Year Onsite Follow-up
In this study the investigators will examine patients who have undergone unilateral ACL reconstruction surgery to determine which structural and functional characteristics of the knee two and ten years post reconstruction…
- Conditions
- Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02717559
- Volunteers
- 225 people
- Sponsor
- Vanderbilt University Medical Center
Patient Reported Outcome, Knee Osteoarthritis
Substitution of the PCL in TKA With UC or PS Design
RCT comparing UC and PS TKA
- Conditions
- Patient Reported Outcome, Knee Osteoarthritis, Knee Arthroplasty
- Trial name
- NCT04679857
- Testing
- TKA
- Where
- Germany
- Volunteers
- 127 people
- Sponsor
- Technische Universität Dresden
Osteoarthritis, Knee Arthritis
Mechanism of IL-10 Pathway-mediated Regulatory B Cell Dysfunction in Osteoarthritis
Our previous work has shown that Treg function is impaired in OA patients, but the cause of Treg deficiency has not been investigated.
- Trial name
- NCT06227195
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shufeng Li
Osteoarthritis, Knee
Comparison of Highly Cross-Linked and Conventional Polyethylene in Total Knee Arthroplasty
To our knowledge, there has been no information on in vivo clinical results of posterior cruciate-substituting arthroplasties using highly cross-linked polyethylene.
- Trial name
- NCT02020057
- Testing
- Total knee arthroplasty
- Volunteers
- 319 people
- Sponsor
- Ewha Womans University
Symptomatic Knee Osteoarthritis
The Effect of Phenolic Compounds in Osteoarthritis; a Nutritional Intervention
The main objective of the study is to elucidate the beneficial effect of a dietary supplement with phenolic compounds in patients with OA versus ascorbic acid.
- Trial name
- NCT04783792
- Testing
- Ascorbic acid / phytochemical supplement, Ascorbic acid
- Where
- 2 sites in Greece
- Volunteers
- 72 people
- Sponsor
- Harokopio University
Osteoarthritis, Knee, Osteoarthrosis of Knee
Univation XM France
The study is set up due to regulatory purposes and to collect routine clinical data of the mobile-bearing implant univation XM. The study is designed as a prospective follow-up study with a historic patient cohort who have been…
- Conditions
- Osteoarthritis, Knee, Osteoarthrosis of Knee, Arthritis Knee, Unicompartmental Knee Arthroplasty
- Trial name
- NCT04199481
- Where
- France
- Sponsor
- Aesculap AG
Osteearthritis, OA
Value of Adding T2 Mapping Routine MRI in Assessment of Knee Articular Cartilage Early Osteoarthritis
This work aims at elucidating the role of MRI complementary T2 mapping in assessment of the articular knee cartilage for improving sensitivity of detection of early stage of osteoarthritis
- Conditions
- Osteearthritis, OA, OA Knee
- Trial name
- T2 mapping OS (NCT07316257)
- Testing
- MRI
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Degenerative Arthritis, Knee Osteoarthritis
Investigator Initiated Trial to Evaluate the Efficacy and Safety of Intra-articular Injection of ADMSC Comared to Negative Control After High Tibial Osteotomy in the Osteoarthritis Patients.
The purpose of this study is to evaluate the efficacy and safety of intra-articular injection of autologous adipose tissue derived mesenchymal stem cells compared after high tibial osteotomy to negative control in the…
- Trial name
- NCT03000712
- Testing
- Autologous Adipose Tissue derived MSCs 1x10^8cells/3ml
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- R-Bio
Total Knee Arthroplasty
Effection of Total Knee Arthroplasty on Knee Joint
The aim of this study is to evaluate the joint position sense of individuals diagnosed with knee osteoarthritis and who have undergone unilateral total knee arthroplasty surgery, and to examine the effect of joint position sense…
- Trial name
- NCT05965765
- Testing
- Total knee arthroplasty, osteoarthritis without surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Cryoneurolysis, Bipolar Radiofrequency Ablation
Cryoneurolysis Versus Bipolar Radiofrequency Ablation of Genicular Nerves for Pain Relief in Symptomatic Knee Osteoarthritis
This study aims to compare the reduction in knee pain between ultrasound-guided cryoneurolysis and bipolar radiofrequency ablation (RFA), as measured by the Numerical Rating Scale (NRS) at predefined follow-up intervals.
- Conditions
- Cryoneurolysis, Bipolar Radiofrequency Ablation, Genicular Nerves, Pain Relief
- Trial name
- NCT07855367
- Testing
- Ultrasound-guided cryoneurolysis, Bipolar radiofrequency ablation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute, Egypt
Osteoarthritis of the Knee
Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthritis of the Knee
The purpose of this study was to evaluate the safety, pharmacokinetics and pharmacodynamics of FX006 in patients with osteoarthritis of the knee.
- Trial name
- NCT01487200
- Testing
- FX006 10 mg, FX006 40 mg, FX006 60 mg
- Where
- 2 sites in Australia
- Volunteers
- 24 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteo Arthritis Knee
Nutrition and Movement to Improve Quality of Life With Knee Osteoarthritis
This project aims to evaluate the effects of an evidence-based training program in combination with an antiinflammatory dietetic intervention on quality of life for patients with knee osteoarthritis
- Trial name
- NUMOQUA (NCT05955300)
- Testing
- Training program, Nutrition therapy
- Where
- 2 sites in Austria
- Volunteers
- 60 people
- Sponsor
- St. Pölten University of Applied Sciences
Knee Osteoarthritis, Osteoarthritis of the Knee
Postmarketing Multicenter Study of Intra-Articular DIART ONE / EASYGO ONE for Knee Osteoarthritis
This study looked at how safe and effective a hyaluronic acid-based injection (called DIART ONE or EASYGO ONE) is for people with knee osteoarthritis.
- Conditions
- Knee Osteoarthritis, Osteoarthritis of the Knee, Degenerative Joint Disease
- Trial name
- NCT06927934
- Where
- Ukraine
- Volunteers
- 55 people
- Sponsor
- Yuria-Pharm
Knee Osteoarthritis, Knee Rheumatism
Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?
One common anesthetic that is performed for total knee replacement surgery is spinal anesthesia with an adductor canal regional block, which involves injecting numbing medication in the thigh region for pain control after…
- Trial name
- NCT03326999
- Testing
- Obturator nerve regional block, Adductor canal regional block, Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Osteoarthritis
Meniscal Tear and Osteoarthritis Risk (MenTOR)
Adults with degenerative meniscal tear receiving arthroscopic surgical management or knee drainage (arthrocentesis) +/- intra-articular steroid injection will be recruited to this non-interventional cohort study.
- Trial name
- MenTOR (NCT02684864)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Oxford
Osteoarthritis, Knee
An Evaluation of a Gender Specific Insole to Provide Relief From Knee Pain Due to Osteoarthritis or General Anterior Knee Pain in Male Subjects When Used in Foot Wear Over a Period of Four Weeks
The primary objective of this trial is to demonstrate the ability of a full length foam insole to provide relief from pain due to osteoarthritis of the knee or general knee pain when used in foot wear for a 4-week period of time.
- Trial name
- NCT03556787
- Testing
- BPI 1000013 (Dr Scholls Insole)
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Bayer
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