Clinical trials: Knee Pain
Total Knee Replacement
Effects of Combined Topical and Systemic Steroid Administrations on Better Early Postoperative Pain Management in Total Knee Arthroplasty
With the aging of population, osteoarthritis of knees and hips has become major orthopaedic problems in Hong Kong. Osteoarthritis of knees and hips is associated with significant pain problems and functional disability.
- Trial name
- NCT03901768
- Testing
- Dexamethasone, Triamcinolone
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Total Knee Arthroplasty
Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain
This study is designed to investigate whether iovera° treatment prior to TKA decreases cumulative participant opioid use over the course of 6 weeks following TKA while maintaining similar levels of pain relief.
- Trial name
- NCT03327220
- Testing
- iovera°
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Knee Osteoarthritis
ESCAPE-pain Programme in Malaysia
The overall aim of this study is to develop an evidence based exercise programme for the management of knee osteoarthritis which is feasible and acceptable to patients and healthcare professionals in Malaysia.
- Trial name
- NCT03379623
- Testing
- ESCAPE-pain Programme
- Where
- 2 sites in Malaysia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Muhammad Kamil Che Hasan
Osteo Arthritis of the Knee, Pain
The Effectiveness of BETY in Knee Osteoarthritis With Intra-Articular Injections
Osteoarthritis (OA) is the most common condition in middle-aged and elderly populations; it causes pain and physical disability and is characterized by cartilage degeneration, changes in bone tissue, inflammation of the synovial…
- Conditions
- Osteo Arthritis of the Knee, Pain, Pain Management, Exercise
- Trial name
- NCT07496203
- Testing
- BETY
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Metal Staple Removal After Total Knee Replacement
Topical Anesthesia for Removal of Stitches After Total Knee Arthroplasty
Lidocaine patch is a safe and effective topical anesthetic agent for removal of metal staples after total knee replacement
- Trial name
- NCT02812602
- Testing
- Lidocaine patch
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Muscle Soreness, Perceived Recovery
Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.
Running is the most popular physical activity worldwide. Although running provides many health benefits, it is often associated with injuries and symptoms such as delayed onset muscle soreness.
- Conditions
- Muscle Soreness, Perceived Recovery, Perceived Exertion, Affective Response
- Trial name
- NCT06225388
- Testing
- Compression socks
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Patellofemoral Pain Syndrome
A Clinical Study in the Use of Orthotics in Treating Pain in the Front of the Knee
Musculoskeletal conditions account for the third leading cause of health systems expenditure in Australia. Patellofemoral pain syndrome or pain about the knee cap is such a condition often treated in primary care.
- Trial name
- NCT00118521
- Testing
- Foot Orthotics, Physiotherapy
- Where
- Australia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Knee Injuries
Femoral/Sciatic Block for Knee Surgery
Knee arthroplasty has a high potential for postoperative pain. This study compares analgesia and postoperative bleeding from intrathecal morphine with the continuous femoral and a single-shot sciatic nerve blockades.
- Trial name
- NCT02882152
- Testing
- femoral nerve blockade, morphine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Patellofemoral Pain Syndrome
Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS…
- Trial name
- NCT00445224
- Testing
- Hip Progressive Resistive Exercise, Quad Progressive Resistive Exercises
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Timothy Uhl
Knee Osteoarthritis
Comparing Exparel & Ropivacaine for Pain Relief in Total Knee Arthroplasty
The purpose of this prospective study is to examine the effect of two local anesthetics used in adductor canal blocks, with relation to pain, analgesic consumption, mobility, and pain related interference with activities and…
- Trial name
- NCT02607579
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Monmouth Medical Center
Pain, Postoperative Complications
Acupuncture for Pain Management After Hip or Knee Arthroplasty
The purpose of this study is to determine whether patients treated with acupuncture post-operatively following knee or hip arthroplasty achieve better pain control as measured by the Visual Analog Scale and pain medication use.
- Trial name
- NCT00455182
- Testing
- Acupuncture, Standard medical care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- HealthEast Care System
Knee Osteoarthritis, Knee Pain Chronic
Evaluation of NMES for Reducing Pain and Improving Functional Outcomes in Knee OA Patients
The present prospective trial is designed to evaluate the efficacy of CyMedica Orthopedics e-vive™ system, a multifunctional electrotherapy device providing neuromuscular electrical stimulation (NMES) for reducing pain and…
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NMES (NCT03980964)
- Testing
- Active NMES
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CyMedica Orthopedics, Inc
Low Intensity Knee Gonalgia
Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort
The purpose of this study is to determine whether the daily eating of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia.
- Trial name
- NCT01303432
- Testing
- Yogurt supplemented with Mobilee, Yogurt
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Osteo Arthritis Knee, Pain, Chronic
Study of the Effects of Photobiomodulation in Patients With Osteoarthritis
PhotoBioModulation (PBM) is a mature science with therapeutic efficacy in humans and animals, and with excellent results in different medical specialties without side effects.
- Conditions
- Osteo Arthritis Knee, Pain, Chronic, Inflammation
- Trial name
- NCT03924128
- Testing
- Photobiomodulation
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Pain, Osteoarthritis, Knee
Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity
The purpose of this research is to evaluate the effects of oxytocin (naturally occurring hormone) given by an intramuscular (IM; into the muscle) injection, has on your parasympathetic nervous system.
- Trial name
- NCT04427709
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteo Arthritis Knee, Quadriceps Muscle Atrophy
Effect of Physical Therapy Modalities in Osteoarthritis
The purpose of this study was to find the most effective treatment out of both techniques; Dry needling and Kinesio Taping for treating knee osteoarthritis (OA) in terms of pain, strength, and balance
- Trial name
- NCT05089253
- Testing
- Dry Needling, Kinesio tapping
- Where
- India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Osteoarthritis
A Study of Orthotic Shoe Inserts for Controlling Osteoarthritic Knee Pain
Osteoarthritis is a degenerative joint disease and is the most common form of arthritis. This study will evaluate the effectiveness of customized shoe inserts in controlling and relieving the pain of knee osteoarthritis.
- Trial name
- NCT00076453
- Testing
- Lateral wedge orthotic shoe inserts, Standard orthotic shoe inserts
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Patellofemoral Pain Syndrome
Trigger Point Dry Needling In Patient With Patellofemoral Pain Syndrome
This study intends to determine the effects of trigger point dry needling in patients with Patellofemoral pain Syndrome.
- Trial name
- NCT03966937
- Testing
- Dry needling, Control
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Polydactyly Toe, Thumb Hypoplasia
Clonidine for Tourniquet-related Pain in Children
This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of…
- Conditions
- Polydactyly Toe, Thumb Hypoplasia, Trigger Finger, Polydactyly; Fingers
- Trial name
- CLOTCH (NCT04564430)
- Testing
- Catapresan, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Postoperative Pain
Total Knee Replacement TIVA With Robotic Arm Assisted
Total knee replacement (TKR) is a commonly performed surgical procedure, and is associated with moderate to severe acute postoperative pain.
- Trial name
- NCT04002271
- Testing
- Propofol, Sevoflurane, Spinal anaesthesia
- Where
- 2 sites in Hong Kong
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Hong Kong