Clinical trials: Knee Pain Swelling
Knee Osteoarthritis, Knee Pain Chronic
Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain
The objective of this investigation is to evaluate the safety of the geniculate artery embolization (GAE) procedure with HydroPearl® Microspheres in 30 patients with knee pain caused by osteoarthritis with 24 months follow-up.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Pain Swelling, Knee Arthritis
- Trial name
- NCT04472091
- Testing
- Genicular artery embolization (GAE)
- Where
- United States
- Sponsor
- Andrew Picel
Pain, Acute, Pain, Chronic
Evaluation of the Effect of the AI500™ SINGLE-DOSE GEL Medical Device in Patients With Reduced Knee Function
Evaluation of the effect of the AI500™ SINGLE-DOSE GEL medical device in patients with reduced knee function
- Conditions
- Pain, Acute, Pain, Chronic, Knee Injuries, Knee Osteoarthritis
- Trial name
- NCT05886608
- Testing
- AI 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Contrad Swiss SA
Total Knee Arthroplasty, Venous Insufficiency of Leg
Efficacy of Diosmin and Hesperidin on Early Rehabilitation After Total Knee Arthroplasty
The goal of this clinical trial is to find out the efficacy of diosmin and hesperidin on postoperative early rehabilitation after primary total knee arthroplasty.
- Trial name
- NCT06753448
- Testing
- Diosmin and Hesperidin Combination
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Ankara Etlik City Hospital
Osteoarthritis
To Study Generic Diclofenac Sodium Topical Gel 1% in the Treatment of Osteoarthritis of the Knee (Degenerative Joint Disease Presented as Joint Pain, Stiffness, Swelling and Restricted Motion).
This is a Randomized, Double-Blind, Placebo-Controlled, Parallel-Design, Multiple-Site Clinical Study to Evaluate the Therapeutic Equivalence of Diclofenac Sodium Gel, 1% (Glenmark Pharmaceuticals Ltd) to Voltaren® Gel…
- Trial name
- NCT02596451
- Testing
- Diclofenac Sodium gel, 1%, Voltaren® Gel
- Where
- 44 sites in United States
- Volunteers
- 1,164 people
- Sponsor
- Glenmark Pharmaceuticals Ltd. India
Degenerative Disease, Meniscus Tear
Effect of NMES as an Add-On to Exercise Program in Degenerative Meniscus Tears
This randomized-controlled trial aims to investigate the effect of NMES as an add-on to an exercise program in patients with degenerative meniscus tears.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Trial name
- NCT06447129
- Testing
- Exercise, Neuromuscular electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Knee Arthritis, Knee Osteoarthritis
Gold Factor on Knee Joint Health and Function
The purpose of this clinical study was to determine whether gold nanoparticles (AuNP) supplement holds clinical value in improving joint health, function, and quality of life for arthritis patients.
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Knee Pain Chronic, Knee Discomfort
- Trial name
- NCT05347602
- Testing
- Gold Factor (Gold Nanoparticles, AuNPs)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- 4Life Research, LLC
Degenerative Disease, Meniscus Tear
The Open Kinetic Chain and Closed Kinetic Chain Strengthening Exercises in Degenerative Meniscus Tears
This randomized-controlled trial aims to compare the effect of open kinetic chain and closed kinetic chain strengthening exercises on pain, function, and health-related quality of life in degenerative meniscus tears.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Trial name
- NCT06447142
- Testing
- Open kinetic chain strengthening exercise, Closed kinetic chain strengthening exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear
Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
- Conditions
- Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear, Meniscus Lesion, Meniscus; Degeneration
- Trial name
- KNEEXO (NCT05261360)
- Testing
- SF-MSC-EX, SF-MSC
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Osteoarthritis Knees Both
Reparel Knee Sleeve vs. TED Hose for Post-op Swelling, Pain and Range of Motion After Total Knee Replacement
This prospective study will evaluate pain, swelling, ROM as well as narcotic use in post-operative total knee arthroplasty patients using novel Non-Compressive Bioactive Garment (NCBG) versus current standard of care gradient…
- Trial name
- NCT04751942
- Testing
- Non-compressive Bioactive Garment, thrombo-embolic deterrent
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Postoperative Swelling After TKA, Postoperative Pain After Tka
Postoperative Cryocuff vs. Conventional Icepack in TKA - What is More Effective in Reducing Pain and Swelling?
Topic/Disease Pattern Postoperative pain and swelling management after knee prosthesis implantation using cryotherapy Objective To determine possible differences in postoperative swelling and pain following primary total knee…
- Trial name
- NCT07627854
- Testing
- cryo cuff treatment, postoperative cooling with conventional ice pack
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Prof. Dr. med. Andreas Halder
Knee Pain Swelling
Painful Total Knee Replacement (TKA) and I-one Therapy
Arthroplasty operations are very frequent and their number is constantly increasing. The success of prosthetic surgery is linked to surgical factors (prosthesis type, prosthesis design, prosthesis material, surgical hand) and…
- Trial name
- NCT06330454
- Testing
- I-ONE
- Where
- 7 sites in Italy
- Volunteers
- 237 people
- Sponsor
- University Hospital of Ferrara
Osteoarthritis, Knee, Osteoarthritis
A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis
The goal of this clinical study is to evaluate the effectiveness of the properties that support the functional state of the joints and the safety of the dietary supplement for food ARTNEO®, oral capsules, in patients with stage…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT05975879
- Testing
- undenaturated collagen type II, methylsulfonylmethane, boswellia serrata, vitamin D3 (cholecalciferol), vitamin C (ARTNEO)
- Where
- 12 sites in Russia
- Volunteers
- 212 people
- Sponsor
- NPO Petrovax
Medial Compartment Osteoarthritis of the Knee
High Tibial Osteotomy (HTO) With or Without Arthroscopy of the Knee Joint
Participants will be randomized to undergo a High Tibial Osteotomy (HTO) with or without a knee scope. Patients will be tested in the Gait Lab, will fill out quality-of-life questionnaires, and have a clinical evaluation done…
- Trial name
- NCT01614288
- Testing
- knee Arthroscopy, No arthroscopy
- Where
- Canada
- Sponsor
- University of Western Ontario, Canada
Knee Pain Chronic, Knee Swelling Pain
Genicular Artery Embolization (GAE) for the Treatment of Chronic Post Knee Arthroplasty Pain
This study seeks to evaluate the safety and efficacy of genicular artery embolization (GAE) as a treatment for patients with chronic pain following primary total knee arthroplasty (TKA) or revision TKA at 6 months as measured by…
- Conditions
- Knee Pain Chronic, Knee Swelling Pain, Arterial Occlusion
- Trial name
- NCT05248308
- Testing
- Embozene Microspheres
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Degenerative Disease, Meniscus Tear
The Video-Based Exercise Programs in Degenerative Meniscus Tears
This randomized controlled trial aims to investigate the efficacy of the video-based exercise programs in patients with degenerative meniscus tears.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Trial name
- NCT05266365
- Testing
- The video-based exercise (VBE), The standard exercise (SE), The hybrid exercise (HE)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Istanbul University - Cerrahpasa
Blood Loss
Fibrin Sealant in Bilateral Simultaneous Total Knee Arthroplasty With Focus on Blood Loss, Pain, Swelling and Strength
The purpose of this study is to measure the effect of fibrin sealant on reducing blood loss, pain and swelling when operated for bilateral total knee arthroplasty.
- Trial name
- NCT01472913
- Testing
- Fibrin sealant, Saline water
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Total Knee Replacement
Influence of Manual Lymph Drainage During Hospitalization on Swelling, Function and Pain in Patients After Total Knee Replacement
To investigate the effects of lymphatic drainage massage performed immediately after total knee replacement in relation to reduction of limb circumference, pain reduction and functional improvement.
- Trial name
- NCT01657149
- Testing
- Lymphatic massage and individual physiotherapy, individual physiotherapy only
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rabin Medical Center
Cartilage Damage
The Influence of Hyaluronic Acid Injection Following Knee Arthroscopy
This is a prospective, double blind randomized controlled trial. In this study we will investigate the influence of hyaluronic acid injection to knee after knee arthroscopy, when known or discovered cartilage damage greater than…
- Trial name
- NCT02640144
- Testing
- Sodium Hyaluronate 1%
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziv Medical Center
Edema
Effect of Compression Therapy on Postoperative Swelling and Pain After Total Knee Arthroplasty
The number of severely obese patients who has knee replacement surgery is rising. Obesity increases the risk of the postoperative swelling.
- Trial name
- NCT03490409
- Testing
- Thigh compression stocking
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Naestved Hospital