Clinical trials: Knee Replacement Arthroplasty
Gait, Unsteady
Perioperative Case Series: Qualitative Evaluation of Gait Cycle and Ground in Knee Arthroplasty Patients
Gait analysis is a quick and powerful tool with a wide range of clinical applications in various fields. However, due to the expensive and highly specialized equipment required, gait studies are mostly limited to academic…
- Trial name
- NCT04268680
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Total Knee Arthroplasty, Total Knee Replacement
Assessing Function and Pain After Total Knee Arthroplasty With Combined Femoral and Popliteal Nerve Block
The goal of this interventional study is to examine whether a pain management technique of combined femoral and popliteal nerve block is effective in total knee arthroplasty patients.
- Conditions
- Total Knee Arthroplasty, Total Knee Replacement, Total Knee Replacement Surgery, Arthritis Knee
- Trial name
- NCT06196359
- Testing
- Combined Femoral and Popliteal nerve block
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- University of Haifa
Knee Osteoarthritis
Gait Analysis of a Lateral-Pivot Design Total Knee Replacement
Previous motion analysis studies have demonstrated excellent ability to distinguish subtle differences in gait between normal subjects and those suffering from arthritis.
- Trial name
- NCT04275362
- Testing
- DJO Empowr PS Knee System, Stryker Triathlon Total Knee System, Biomet Vanguard Complete Knee System
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- More Foundation
PONV
Aprepitant to Improve Same Day Discharge for TKA
The purpose of this research is to study whether adding an FDA approved medication called aprepitant (a medication given to patients like you to reduce or eliminate nausea and vomiting) to the usual treatment to prevent nausea…
- Trial name
- NCT07639723
- Testing
- Aprepitant Injection, Ondansetron (Zofran), Dexamethasone
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Endeavor Health
Myocardial Ischaemia
Comparison of the Effect of Two Anaesthesia Methods in Preventing Perioperative Myocardial Infarcation in Patients With Cardiac Risk Undergoing Total Knee Arthroplasty
Comparison of the effect of two anaesthesia methods in preventing perioperative myocardial infarction in patients with cardiac risk undergoing total knee arthroplasty
- Trial name
- NCT05340946
- Testing
- general anaesthesia, spinal anaesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Knee Osteoarthritis, Arthropathy of Knee Joint
The Effect of Exercise Training on Muscle Mass in Patients With Total Knee Arthroplasty
Background: Total knee arthroplasty (TKA) is one of the most common operations in orthopedics. After surgery, the decline of bone mineral density and muscle mass was proved, oral bisphosphonate is commonly used to prevent BMD…
- Trial name
- NCT03339323
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 210 people
- Sponsor
- Chang Gung Memorial Hospital
Knee Arthroplasty
The Energize! Study for Adults With Knee Replacement
The purpose is to examine the effects of an online physical activity program on moderate to vigorous intensity physical activity, pain, and physical function in adults with knee replacement at 3 months (post-intervention) and 6…
- Trial name
- NCT06096727
- Testing
- Energize!
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Arthroplasty, Replacement, Knee, Chronic Pain
Effects of Exercise and Education in Patients With Chronic Pain After Total Knee Replacement
The purpose of the study is to investigate whether a 12-week neuromuscular rehabilitation program (NEMEX-TJR) combined with pain neuroscience education (PNE) provides greater pain relief, improvement in physical function and…
- Trial name
- NCT03886259
- Testing
- Neuromuscular exercises (NEMEX-TJR) and pain neuroscience education, Pain neuroscience education
- Where
- 3 sites in Denmark
- Volunteers
- 71 people
- Sponsor
- Aalborg University
Postoperative Oral Carbohydrates, Postoperative Recovery
Effect of Early Postoperative Oral Carbohydrate on Postoperative Recovery of the Unilateral Knee Arthroplasty
To evaluate the effect of early postoperative oral carbohydrate on postoperative recovery of the unilateral knee arthroplasty
- Conditions
- Postoperative Oral Carbohydrates, Postoperative Recovery, Unilateral Knee Arthroplasty
- Trial name
- NCT05867264
- Testing
- Early drinking water, Early consumption of carbohydrates, Late feeding group
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- Hongwei Shi
Thromboembolism, Arthroplasty Replacement, Knee
Safety Study of Stopping Thromboprophylaxis Based on Ultrasound Results After Total Knee Replacement
The purpose of this study is to determine whether stopping Low Molecular Weight Heparin (LMWH) thromboprophylaxis is safe after total knee joint replacement.
- Trial name
- NCT00362492
- Testing
- Bilateral ultrasound examination 7+/- 2 after surgery
- Where
- 17 sites in France
- Volunteers
- 850 people
- Sponsor
- University Hospital, Caen
Blood Loss
Tranexamic Acid for Unilateral Total Knee Arthroplasty
Total knee arthroplasty is often associated with excessive postoperative bleeding due to increased fibrinolysis. Hence, the objective of the proposed of this multicentre study is to determine the peri-operative bleeding comparing…
- Trial name
- TRANEXTOP (NCT01594671)
- Testing
- Tranexamic Acid, haemostasia
- Where
- 2 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Total Knee Arthroplasty
The Ultrasonographic Measurement of Quadriceps Muscle Thickness and the Shape of the Femoral Nerve in Patients Undergoing Total Knee Arthroplasty: an Observational Study
For each individual, the femoral nerve shows various shapes and locations. This is because the femoral nerve is located on top of the iliacus muscle, so the shape and location of the femoral nerve seems to be related to the…
- Trial name
- NCT05382507
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Knee Osteoarthritis
Pre-Operative Exercise Therapy and Patient Education Before Total Knee Replacement
The goal of this multi-center randomized controlled trial is to investigate the effect of pre-operative exercise therapy and education for patients awaiting knee replacement surgery on subjective knee function, patient…
- Trial name
- PROTEKT (NCT06290336)
- Testing
- Pre-operative exercise therapy and education, Standardized pre-operative information session
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- Linkoeping University
PAIN
Effect of Oral Pregabalin on Spinal Neurotransmitters in Patients Undergoing Knee Replacement
This study involves research. Pregabalin is a Food and Drug Administration (FDA) medication approved in the United States for the treatment of nerve pain related to diabetes and post-herpetic neuralgia "shingles", and for…
- Trial name
- NCT00729690
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Asokumar Buvanendran
Arthropathy of Knee, Spinal Anesthesia
Dexmedetomidine on Tourniquet Induced -Systemic Effects
Eighty patients were randomly assigned to either control (CON) or dexmedetomidine (DEX) group. DEX group received a loading dose of 0.5 µg/ kg of intravenous dexmedetomidine over 10 minutes, followed by a continuous infusion of…
- Conditions
- Arthropathy of Knee, Spinal Anesthesia, Tourniquet, Ischemia-reperfusion Injury
- Trial name
- NCT04307290
- Testing
- Dexmedetomidine Hydrochloride, or Saline
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Wonkwang University Hospital
Osteoarthritis, Knee Arthroplasty
Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty
Patients undergoing primary total knee replacement will receive either motor sparing knee block to be performed by anesthesia or periarticular local anesthetic infiltration at the end of surgery by surgeons to assess pain relief…
- Conditions
- Osteoarthritis, Knee Arthroplasty, Pain Management
- Trial name
- NCT02540070
- Testing
- Periarticular, Motor free, Motor free with dex
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Venous Thromboembolism
Multicenter Registry for Effectiveness Analysis of ActiveCare+S.F.T® Mobile Compression Device for Thrombosis Prevention in Hip and Knee Arthroplasty
Venous thromboembolic events (VTE), either deep vein thromboses or pulmonary emboli, are important complications in patients undergoing knee or hip arthroplasty.
- Trial name
- ACOR (NCT01984190)
- Where
- 10 sites in United States
- Volunteers
- 411 people
- Sponsor
- Medical Compression Systems
Knee Osteoarthritis (Knee OA)
Evaluation of a Preoperative Education in Total Knee Arthroplasty
The benefit of preoperative rehabilitation treatment combining physiotherapy and targeted education for patient undergoing Total Knee replacement (TKR) is now well known.
- Trial name
- EPOP (NCT01747759)
- Testing
- Kruskal-Wallis and qualitative parameters
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hip Prosthesis Infection, Knee Prosthesis Infection
CERAMENTTM|G and V in the Management of Hip and Knee Arthroplasty Revisions (Revision Arthroplasty Italy)
Open-label, multicentre, prospective cohort, observational clinical trial with a retrospective control group to evaluate the effectiveness and safety of CERAMENTTM| G or V used for filling of bone defects in the tibia and / or…
- Trial name
- NCT03389646
- Testing
- CERAMENT G V
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Total Knee Replacement
Effects of OEP on Rehabilitation Outcomes on TKR Patients
The aim of this research is to assess the effects of the Otago Exercise Program on Rehabilitation outcomes of balance strength and functional outcomes of post Total Knee Replacement patients.
- Trial name
- NCT06190977
- Testing
- Otago Exercise Program, General TKR pprotocol
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.