Clinical trials: Knee Rheumatism
Knee Osteoarthritis
Strengthening Program for Foot-ankle Muscles in People With Knee Osteoarthritis
The main objective of this trial is To evaluate the effect of an ankle and foot muscle strengthening program on pain, analgesic consumption, functionality, and lower limb biomechanics during gait in individuals with knee…
- Trial name
- NCT04154059
- Testing
- Intervention Group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Sao Carlos
Knee Osteoarthritis
Cingal Study for Knee Osteoarthritis
The purpose of this study is to see if a single injection of Cingal into the knee provides safe relief of pain caused by osteoarthritis.
- Trial name
- NCT01891396
- Testing
- Hyaluronic Acid and TH (Cingal®), Hyaluronic Acid (Monovisc®), Saline
- Where
- 27 sites in Bulgaria, Canada and 3 more
- Volunteers
- 368 people
- Sponsor
- Anika Therapeutics, Inc.
Knee Osteoarthritis
Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis
This is a single-center, prospective, randomized, single-blind, comparator therapy, parallel group study for symptomatic patients diagnosed with knee osteoarthritis.
- Trial name
- NCT03491761
- Testing
- PRP Treatment, HA Treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Endeavor Health
ERAS, Knee Osteoarthritis
Enhanced Recovery After Surgery Protocols in Total Knee Arthroplasty Via Midvastus Approach
The study aimed to investigate the impact of enhanced recovery after surgery (ERAS) protocols on the clinical effect of total knee arthroplasty (TKA) via the midvastus approach
- Trial name
- NCT04873544
- Testing
- ERAS protocols for TKA
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Knee Osteoarthritis, Knee Pain Chronic
Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain
Dorsal root ganglion stimulation (DRG-S) may be able to treat mechanical pain caused by tissue injury or damage such as trauma or arthritis in addition to pain caused by nerve dysfunction or injury.
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis, Knee Arthropathy
- Trial name
- NCT05103527
- Testing
- Dorsal Root Ganglion Stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kenneth B Chapman
Osteo Arthritis Knee, Sarcopenia
HIGH AND LOW INTENSITY PROGRESSIVE RESISTED EXERCISES ON PAIN, RANGE OF MOTION AND FUNCTIONAL DISABILITY
The study will be randomized controlled trial. This study will be conducted in University of Lahore Teaching Hospital, Lahore, Pakistan.
- Trial name
- NCT05190380
- Testing
- HIGH INTENSITY PROGRESSIVE RESISTED EXERCISE, LOW INTENSITY PROGRESSIVE RESISTED EXERCISE
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore
Knee Osteoarthritis
RF TKA Prehabilitation
The purpose of this study is to compare the effects of the radiofrequency applied to the sensory innervation of the knee, with respect to a control group (standard therapy), in a prehabilitation program aiming to improve the…
- Trial name
- NCT03758300
- Testing
- Radiofrequency
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Knee Osteoarthritis
Comparison Between Medial Pivot Versus Symmetric Insert Total Knee Arthroplasty
The functional outcome and longevity of total knee arthroplasty (TKA) is still a concern. Despite various developments in TKA designs, including fixed or mobile bearing, cruciate retaining or posterior stabilized, multi or single…
- Trial name
- NCT04769544
- Testing
- total knee arthroplasty with medial pivot tibial insert or symmetrical insert
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Elda University Hospital
Knee Osteoarthritis, Total Knee Arthroplasty
Robotic-Assisted Total Knee Arthroplasty: Cruciate-Retaining Versus Bi-Cruciate Stabilized
The global prevalence of osteoarthritis of the knee with total knee arthroplasty performed is projected to substantially rise in the near future.
- Trial name
- NCT06838663
- Testing
- Robotic assisted Cruciate-Retaining (CR) TKA procedures, Robotic assisted Bi-Cruciate Stabilized (BCS) TKA procedures
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis of the Knee
Serum and Synovium Protease Inhibitor Levels in Primary and Secondary Osteoarthritic Joints
Osteoarthritis (OA) is the irreversible degeneration of articular cartilage and underlying bone. It poses a major healthcare problem as it is the leading cause of joint disease and disability in the United States.
- Trial name
- NCT01613833
- Testing
- Blood Draw, Joint Aspirate Harvest
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Scuderi, Gaetano J., M.D.
Osteoarthritis, Total Knee Arthroplasty
Effectiveness of Passive and Active ROM Exercises Following TKA
The purpose of the study is to determine the effectiveness of new interventional approaches in the early postoperative phase following total knee arthroplasty (TKA).
- Trial name
- NCT02062138
- Testing
- continuous passive motion (CPM), controlled active motion (CAM I), controlled active motion (CAM II)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Rostock
Osteoarthritis
Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
Clinical study to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma.
- Trial name
- NCT01075230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Exactech
Obesity, Knee Osteoarthritis (OA)
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and knee osteoarthritis.
- Trial name
- AMAZE 5 (NCT07481630)
- Testing
- NNC0487-0111
- Where
- 82 sites in United States, Australia and 8 more
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Knee Osteoarthritis, Survey, Family Life
Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals
Although knee pain is prevalent among community-dwelling older adults, little is known about how people in general handle their pain.
- Conditions
- Knee Osteoarthritis, Survey, Family Life, Complementary Therapies, Pain
- Trial name
- NCT03472300
- Testing
- Survey about knee pain and treatment
- Where
- Denmark
- Volunteers
- 9,600 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital
Cartilage Damage
The Influence of Hyaluronic Acid Injection Following Knee Arthroscopy
This is a prospective, double blind randomized controlled trial. In this study we will investigate the influence of hyaluronic acid injection to knee after knee arthroscopy, when known or discovered cartilage damage greater than…
- Trial name
- NCT02640144
- Testing
- Sodium Hyaluronate 1%
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziv Medical Center
Cartilage Degeneration, Rotator Cuff Tear
Use of MRI Labeling Technique to Track Mesenchymal Stem Cell Survival in Orthopaedic Conditions
The primary objective is to determine whether a surgical intervention involving removing of the calcified cartilage cap in patients with Grade II Kellgren-Lawrence osteoarthritis influences the incorporation of labeled bone…
- Conditions
- Cartilage Degeneration, Rotator Cuff Tear, Osteoarthritis, Knee
- Trial name
- NCT03648463
- Testing
- arthroscopy of the affected knee/ Bone Marrow Concentrate Injection
- Sponsor
- Stanford University
Knee Osteoarthritis
Muscle Activation in Knee Osteoarthritis
Muscle activity, as a possible fundamental cause of functional limitation, has been extensively investigated in knee osteoarthritis (KOA).
- Trial name
- NCT05870033
- Testing
- Electromyography (EMG) measurement
- Where
- Hungary
- Volunteers
- 70 people
- Sponsor
- University of Pecs
Osteoarthritis of Knee
Efficacy of Peripheral Magnetic Stimulation to Reduce Pain in Knee Osteoarthritis.
To investigate effects of repetitive peripheral magnetic stimulation (PMS) on pain reduction in knee osteoarthritis
- Trial name
- NCT05484752
- Testing
- Repetitive Peripheral Magnetic Stimulation, Education
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Osteoarthritis
Meloxicam SoluMatrix® Capsules vs Meloxicam Tablets to Treat Osteoarthritis Pain
The purpose of this study is to evaluate the safety and efficacy of a low dose and a high dose of Meloxicam SoluMatrix® Capsules versus Meloxicam Tablets for the treatment of pain due to osteoarthritis of the knee or hip.
- Trial name
- NCT02405793
- Testing
- Meloxicam Test Capsules, Meloxicam Tablets
- Sponsor
- Iroko Pharmaceuticals, LLC
Osteoarthritis, Knee, Knee Injuries
Impact of Mulligan Squeeze Technique on Meniscal Derangement in Knee Osteoarthritis Patients
The objective of this study is to find out the effects of Mulligan's Squeeze technique added as a complementary treatment to the conventional physiotherapy for the management of meniscal derangement in knee osteoarthritis…
- Conditions
- Osteoarthritis, Knee, Knee Injuries, Meniscus; Derangement, Meniscus Tear
- Trial name
- NCT06391047
- Testing
- Mulligan's Squeeze Technique - manual therapy, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad