Clinical trials: Knee Surgeries
Knee Disease, Knee Osteoarthritis
Ultrasound Guıded Adductor Canal Block vs Perıcapsular Nerve Group Block in Knee Artroplasty
Knee arthroplasty surgery numbers are increasing depending on joint deformities and cartilage degenerations. Severe postoperative pain may occur in these patients due to surgery and the placed prosthesis.
- Conditions
- Knee Disease, Knee Osteoarthritis, Knee Arthropathy
- Trial name
- NCT06203483
- Testing
- Adductor canal block, PENG block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Knee Replacement, Arthropathy of Knee
Investigating the Effect of Dronabinol on Post-surgical Pain
This study is designed to investigate the effect of dronabinol on post operative pain in patients undergoing total knee replacement (for their own clinical care).
- Trial name
- NCT04099355
- Testing
- Dronabinol 5mg Cap, Non-active comparator
- Where
- United States
- Sponsor
- New York State Psychiatric Institute
Ligament Knee Injury, Anterior Cruciate Ligament Rupture
Optimized Rehabilitation After Anterior Cruciate Ligament Before Returning to Sport
Following reconstruction of the anterior cruciate ligament (ACL), a standardized rehabilitation protocol is carried out by a physiotherapist.
- Trial name
- ORACL-Run (NCT05323474)
- Testing
- Usual rehabilitation, Rehabilitation optimized
- Where
- 8 sites in France, Switzerland
- Volunteers
- 432 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anterior Cruciate Ligament Rupture
Comparison of Different Anterior Cruciate Ligament Surgery Techniques in Skeletally Immature Patients.
This cohort study compares to groups of patients with reconstruction of anterior cruciate ligament (ACL). Patients in group 1 had ACL-reconstruction in the years 2001-2010 with a transphyseal drilling technique.
- Trial name
- NCT04644497
- Testing
- ACL-reconstruction
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Arthropathy of Knee, Complication of Surgical Procedure
Effect of Plugging the Registration Pin Tract in Robotic-assisted Knee Surgery
Introduction: Complications of robotic-assisted total knee arthroplasty (TKA) seem to be rare and consist mainly of infections or fractures.
- Trial name
- NCT05638386
- Testing
- Bone plug
- Where
- Netherlands
- Volunteers
- 384 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Acupuncture Analgesia, Acupuncture
ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery
Post-operative analgesia after total knee arthroplasty (TKA) has always been a challenge in the anesthesiological setting, having to combine good pain control and the need for early mobilization, both factors that can affect the…
- Conditions
- Acupuncture Analgesia, Acupuncture, Acupuncture Therapy, Total Knee Anthroplasty
- Trial name
- ACU_Knee (NCT07123805)
- Testing
- Acupuncture group
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Total Knee Replacement Surgery
The Impact of Sedation Depth Monitoring for Cognitive Functions and Early Rehabilitation After Major Joints Arthroplasty
Spinal anesthesia is applied for patients undergoing total elective knee replacement surgery. It reduces rates of postoperative complications, improves postoperative pain management, rehabilitation is started earlier and patients…
- Trial name
- NCT06241859
- Testing
- Dräger Infinity Delta series monitor (Dräger, Germany) with Covidien BIS LoC 2 channel module and BIS Quatro (4 electrodes) sensor (Covidien, Ireland)
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Lithuanian University of Health Sciences
Anterior Cruciate Ligament Injury
Acute Anterior Cruciate Ligament Rupture; RecOnsTruction Or Repair?
To investigate the hypothesis that suture repair of a ruptured vkb, combined with a dynamic intraligamentary stabilization and microfracture of the femoral notch, results in at least equal effectiveness compared with an ACL…
- Trial name
- ROTOR (NCT02310854)
- Testing
- ACL Repair, ACL reconstruction
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Knee Prosthetic Surgery, Robotic Assistance
Clinical and Radiological Results in Robotic Assisted Knee Prosthetic Surgery With ROSA® Knee System
Comparing clinical and radiological results of patients after prosthetic surgery conventionally with no robotic assistance and ROSA® Knee prosthetic surgery robotic assistance.
- Trial name
- NCT05365022
- Testing
- ROSA® System Robotic Assisted Knee Prosthetic Surgery
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Borja Alcobía-Díaz MD, PhD
Cerebral Palsy, Care Giving Burden
Caregiver Burden in Cerebral Palsy Undergoing Hip and Knee Surgery
The aim of this observational study was to obtain information about the change in the burden of care of parents of children with cerebral palsy after hip and knee surgeries.
- Trial name
- Caregiver CP (NCT06224322)
- Testing
- Assesment Scale
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Knee Arthroscopic Surgery
Effect of Dexmedetomidine Combined With FNB/ACB on Sleep Quality After Knee Surgery
The goal of this randomized, double-blind, placebo-controlled, 2×2 factorial trial is to evaluate the effect of intraoperative dexmedetomidine combined with either femoral nerve block (FNB) or adductor canal block (ACB) on…
- Trial name
- NCT07767383
- Testing
- ropivacaine (local infiltration), Dexmedetomidine, Femoral Nerve Block
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nantong University
Total Knee Replacement Surgery
Iodine Impregnated Incision Drapes and Bacterial Recolonization in Simulated Knee Surgery. A Controlled Randomized Experimental Trial.
This study evaluates the effect of Iodine-impregnated self-adhesive plastic drapes (IIAD) on the quantity of skin bacteria, which is a known factor in the development of surgical site infections in orthopedic surgery.
- Trial name
- NCT02342561
- Testing
- Ioban 2 incision drape, 3M
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Knee Arthroplasty
Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty.
Osteoarthritis of the knee is a common disease of the elderly and knee arthroplasty is indicated in severe cases to improve long term pain and function.
- Trial name
- NCT03944005
- Where
- 2 sites in Canada, United Kingdom
- Sponsor
- Western University, Canada
Knee Replacement Surgery
The Effect of a Prolonged Peripheral Nerve Block on the Level of Pain After a Knee Replacement
The aim of this study is to examine the effect of a prolonged peripheral nerve block (utilizing continuous adductor canal block) on the level of pain after a knee replacement surgery
- Trial name
- NCT06382285
- Testing
- Continues peripheral block
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Knee Pain Swelling
Knee Swelling Under Use of Compression Stockings After Outpatient Surgery
Outpatients who undergo knee surgery are designated two different clinical study groups. Group A receives common wrapping after surgery to the first postsurgical day and will be provided with compression stockings for the…
- Trial name
- NCT02096562
- Testing
- Patients use compression stockings for 10 days after surgery, normal therapy - no compression stockings
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University of Rostock
Anterior Cruciate Ligament Injuries, Postoperative Pain
Multimodal Analgesia vs. Femoral Block in ACL Surgery
This study aims to compare the effects of a preemptive multimodal intravenous analgesia protocol and a femoral triangle block on early postoperative rehabilitation compliance in patients undergoing anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Postoperative Pain, Pain, Postoperative
- Trial name
- MAPvsFTB (NCT06936995)
- Testing
- Preemptive Multimodal Intravenous Analgesia, Femoral Triangle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara University
Hip Osteoarthritis, Hip Arthritis
Evaluating XPERIENCE™ Advanced Surgical Irrigation
A prospective, multi-center, double-arm, parallel, interventional, randomized, controlled clinical trial to assess the rate of periprosthetic joint infection (PJI) in patients undergoing primary total knee arthroplasty (TKA)…
- Conditions
- Hip Osteoarthritis, Hip Arthritis, Knee Osteoarthritis, Knee Arthritis
- Trial name
- XPERIENCE (NCT05543941)
- Testing
- XPERIENCE Advanced Surgical Irrigation, Dilute Betadine
- Where
- 8 sites in Canada
- Volunteers
- 7,600 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Knee, Osteoarthritis, Hip
Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing…
- Trial name
- NCT07439575
- Testing
- Barbed Suture Wound Closure, Conventional Suture Wound Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bahattin Kemah
Degenerative Osteoarthritis, Rheumatoid Arthritis
Orthopilot Elite Post-Market Clinical Follow-Up
Prospective, multicenter, observational, comparative clinical trial on the equivalence of two different OrthoPilot® navigation system generations applied for computer-assisted total knee arthroplasty
- Conditions
- Degenerative Osteoarthritis, Rheumatoid Arthritis, Posttraumatic Arthropathy, Instability, Joint
- Trial name
- NCT03817632
- Testing
- Computer assisted primary total knee replacement with OrthoPilot FS101 navigation system and Software 5.1, Computer assisted primary total knee replacement with OrthoPilot Elite navigation system and Software 6.0
- Where
- 3 sites in Germany
- Volunteers
- 217 people
- Sponsor
- Aesculap AG
Arthropathy of Knee Joint, Arthropathy of Hip Joint
A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery
The mission is to develop novel interventions to improve cognitive function, and thereby reducing delirium in hospitalized patients to improve perioperative outcomes.
- Trial name
- NCT03601728
- Testing
- personalized prehabilitation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Pennsylvania