Clinical trials: Kono S Anastomosis
Ileocolic Crohn Disease, Kono S Anastomosis
The Remeasure Trial
Aim of the present study is to compare a stapled, functional end-to-end, ileo-colic anastomosis with removal of the mesentery vs the manual, functional end-to-end, ileo-colic Kono-S anastomosis with mesentery preservation, in…
- Conditions
- Ileocolic Crohn Disease, Kono S Anastomosis, Resection of the Mesentery
- Trial name
- NCT07164209
- Testing
- Excision of the mesentery: the mesentery is fully dissected and excised to the limit of macroscopic "fat wrapping", where mesenteric fat is inflamed and extends beyond its normal anatomical distribut, Kono S Anastomosis
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Azienda Ospedaliera Ordine Mauriziano di Torino
Crohn Disease
Surgical Prevention of Anastomotic Recurrence by Excluding Mesentery in Crohn's Disease
Kono and collegues have described a new anastomotic technique to restore bowel contintuity after ileocecal resection for Crohn's disease (CD).
- Trial name
- SuPREMeCD (NCT02631967)
- Testing
- Kono anastomosis, Stapled side-to-side anastomosis
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Federico II University
Crohn Disease
Comparing Hand-sewn (END-TO-END or Kono-S) to Stapled Anastomosis in Ileocolic Resection for Crohn's Disease
The aim of this multicenter randomised controlled trial is to compare the handsewn (end-to-end and Kono-S) to the stapled side-to-side ileocolic anastomosis after ileocolic resection for Crohn's disease with respect to 6 months…
- Trial name
- END2END (NCT05578235)
- Testing
- stapled side-to-side anastomosis, Handsewn anastomosis
- Where
- Netherlands
- Volunteers
- 165 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chrohn's Disease
GPX4 Expression After Kono-S vs Conventional Anastomosis
Crohn's disease is a long-term condition that causes inflammation in the bowel. Many people with Crohn's will need surgery at some point to remove damaged sections of intestine.
- Trial name
- NCT07772037
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Crohn Disease, IBD
Comparing Manual Versus Stapled Side to Side Ileocolic Anastomosis in Crohn's Disease
RESEARCH QUESTION Are handsewn (end to end and Kono S side to side) anastomoses superior to side to side stapled anastomosis after ileocolic resection for Crohn's disease with respect to endoscopic recurrence, gastrointestinal…
- Conditions
- Crohn Disease, IBD, Ileocolitis, Crohn's Ileocolitis
- Trial name
- HAND2END (NCT05246917)
- Testing
- Handsewn anastomosis
- Where
- Italy
- Volunteers
- 189 people
- Sponsor
- IRCCS San Raffaele
Crohn's Disease
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis
This study proposes a randomized prospective study comparing the Kono-S anastomosis to the standard side-to-side anastomosis.This will be a multi-center randomized prospective trial.
- Trial name
- NCT03256240
- Testing
- side-to-side functional end anastomosis, Kono-S analstomosis
- Where
- 15 sites in United States, Belgium and 4 more
- Volunteers
- 600 people
- Sponsor
- Weill Medical College of Cornell University
Crohn Disease, Recurrence
Comparison of Two Stapled Antimesenteric Anastomosis for CD: a Randomized Control Trial Study
The postoperative recurrence of Crohn's diseases (CD) remains high. Stapled anti-mesenteric functional end-to-end anastomosis was safe for CD patients. Its impact on the postoperative recurrence of CD was unknown.
- Trial name
- NCT05658081
- Testing
- Kono-S group, Side-to-side group
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Jinling Hospital, China
Crohn Disease
KONO-S Anastomosis Compared to Conventional Ileocolonic Anastomosis to Reduce Recurrence in Crohn's Disease
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) currently affecting one person in a thousand in France. It can lead to numerous digestive complications such as fistulas, abscesses or stenosis.
- Trial name
- KOALA (NCT05974358)
- Testing
- Kono-S anastomosis, Conventional anastomosis for ileocolonicresection of Crohn's disease
- Where
- 15 sites in France
- Volunteers
- 226 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Crohn Disease (CD), Crohn Disease of Ileum
Laparoscopic Right Hemicolectomy for Crohn's Disease of the Terminal Ileum Utilizing the Mesenteric Excision and Exclusion
This study is designed for patients requiring surgery for Crohn's disease of the terminal ileum. A combination of laparoscopic segmental right colectomy with extended mesenteric excision and the Kono-s anastomosis will be…
- Conditions
- Crohn Disease (CD), Crohn Disease of Ileum, Kono S Anastomosis, Extended Mesenteric Excision
- Trial name
- NCT07231601
- Testing
- Mesenteric excision and exclusion
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tzaneio General Hospital