Clinical trials: L-arginine
Oligohydramnios
Comparison Between Treatments of Oligohydramnios
Based on previous studies, Both sildenafil and L-arginine helped to improve idiopathic oligohydramnios. In this study, Level of improvment of oligohydramnios will be compared.
- Trial name
- NCT07135037
- Testing
- Sildenafil 25 MG, L-Arginine, 1000 Mg Oral Tablet
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Hypercholesterolemia, Postmenopause
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
Estrogen therapy has been associated with reduced risk of coronary heart disease events in observational studies of postmenopausal women.
- Trial name
- NCT00001752
- Testing
- L-arginine, Estrogen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypersensitivity
Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hypersensitivity
The objective of this study is to assess clinical efficacy of a toothpaste containing 8% arginine (Colgate-Palmolive Company, New York, NY, USA) to provide dental hypersensitivity relief (tactile and air blast) in comparison to…
- Trial name
- NCT07257042
- Testing
- Toothpaste containing 8% Arginine, Colgate Cavity Protection Toothpaste
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Overweight, Hypertriglyceridemic Waist
Effect of Arginine Supplementation in the Metabolic Syndrome
The purpose of this study is to determine whether oral supplementation with one form of arginine improves vascular endothelial function in healthy subjects with risk factors associated with the metabolic syndrome
- Trial name
- NCT02354794
- Testing
- One form of arginine
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Plaque, Dental
Arginine Plaque Metabolism Pilot Clinical Study
Proof of concept clinical study to measure plaque metabolism and the prebiotic efficacy of arginine-containing toothpaste.
- Trial name
- NCT06954779
- Testing
- Colgate Cavity Protection, TOM's Superior Sensitivity Relief Toothpaste
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Pain
A Bioequivalence Study of Two Ibuprofen Arginine Granules 400 mg Formulations Under Fasting and Fed Conditions in Chinese Healthy Adult Subjects
The primary purpose of this study is to demonstrate the bioequivalence of two ibuprofen arginine granules 400 milligram (mg) formulations under fasting and fed conditions in Chinese healthy adult participants.
- Trial name
- NCT05737069
- Testing
- Ibuprofen arginine granules 400 mg, Ibuprofen arginine granules 400 mg (Spedifen)
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- HALEON
Diabetes Mellitus, Type 1
Positron Emission Tomography (PET) Imaging of Pancreatic Beta-Cell Mass in Healthy and Type 1 Diabetic Patients
Pancreatic Islet beta-cells are responsible for synthesizing and secreting appropriate amounts of insulin to regulate blood glucose levels. One factor in the development of diabetes is the loss of beta-cells.
- Trial name
- NCT00958997
- Testing
- 18F-FP-DTBZ (18F-AV-133), Arginine-hydrochloride
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Yale University
Physiologically Healthy Adult Male Participants
Lysine Oxidation in Response to Arginine Supplementation
This research study is investigating if consuming more of one amino acid (arginine) influences the digestion and absorption of another amino acid (lysine) due to competition in digestion, in a healthy adult population.
- Trial name
- NCT02499926
- Testing
- Arginine
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy Female Participants
A Study to Evaluate the Metabolism, the Routes and Extent of Elimination, and Drug Levels of [14C]Navlimetostat (BMS-986504) in Healthy Female Participants
The purpose of this study is to evaluate the metabolism, the routes and extent of elimination, and drug levels of [14C]Navlimetostat (BMS-986504) in healthy female participants
- Trial name
- NCT07777133
- Testing
- Navlimetostat, [14C]Navlimetostat
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healhty
Oromucosal Oxytocin and Vasopressin Modulation of Emotional Face Attention
The goal of this clinical trial is to learn how 24 IU oxytocin (OT) and 24 IU arginine vasopressin (AVP), administered through the oral mucosa, affect attention to emotional faces and related brain activity in healthy adults.
- Trial name
- NCT07838493
- Testing
- Oxytocin (OT), Arginine Vasopressin (AVP)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Spirometry, Qadriceps Muscle
The Effect of Orally Administered L- Arginine on Quadriceps Strenght in Healthy Smokers
The study will investigate changes in certain locomotor parameters as early predictors of disease in smokers who are prone to develop chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT04643600
- Testing
- L-Arginine, 500 Mg Oral Capsule
- Where
- Croatia
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Goranka Radmilović
Arginine Vasopressin Deficiency, Central Diabetes Insipidus
Effects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy Controls
The study aims to investigate whether intranasal oxytocin (OXT) improves sexual well-being in patients with Arginine Vasopressin Deficiency (AVP-D).
- Conditions
- Arginine Vasopressin Deficiency, Central Diabetes Insipidus, Oxytocin Deficiency
- Trial name
- OxyPLEASURE (NCT06808516)
- Testing
- Oxytocin nasal spray
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Ergogenic Support and Performance
Acute Effects of BCAA and L-Arginine on Performance in Elite Soccer Players
his study aims to investigate the acute effects of a single pre-exercise dose of branched-chain amino acids (BCAA) and L-arginine supplementation on anaerobic performance, sprint speed, agility, lactate response, and…
- Trial name
- CST-SP (NCT07347509)
- Testing
- BCAA, L-Arginine, bcaa and l arginine
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Periodontal Diseases
Evaluation of Biomarker Levels in Gingival Crevicular Fluid of Patients With Different Periodontal Diseases
Objectives: The aim of this study is; detection of peptidyl arginine deiminase4 (PAD4), galectin-3 and tumor necrosis factor alpha (TNF-α) levels in gingival crevicular fluid (GCF) samples of periodontally healthy, gingivitis and…
- Trial name
- NCT04777487
- Testing
- GCF obtaining
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Erectile Dysfunction
Daily Oral L-arginine Plus Tadalafil in Diabetic Patients With Erectile Dysfunction
Tadalafil is an effective oral therapy in erectile dysfunction. L-arginine is a pro drug that increase the level of nitrous oxide in the smooth muscles so can increase the strength and duration of erection.
- Trial name
- NCT03834610
- Testing
- L-arginine 5 gm oral caps, Tadalafil 10 MG, serum testosterone level
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Healthy
Effects of L-Arginine and Citrulline Malate Supplementation on Sport Performance in Physically Active Men
In this randomized, double-blind, placebo-controlled trial we investigated the effects of combined L-arginine (Arg) and citrulline-malate (CM) supplementation on aerobic, anaerobic, and high-intensity interval training in…
- Trial name
- ReachSci (NCT06938126)
- Testing
- L-Arginine and Citrulline-Malate Supplementation
- Where
- Hungary
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hungarian University of Sports Science
Covid19
Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC
COVID-19 infection was shown to cause endothelial dysfunction . At the level of the endothelium the pathophysiological mechanisms have been hypothesized and were divided into pro-coagulant, pro-inflammatory, anti-fibrinolytics…
- Trial name
- MEDIC-LAUMC (NCT04631536)
- Testing
- Atorvastatin + L-arginine + Folic acid + Nicorandil + Nebivolol
- Where
- Lebanon
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lebanese American University Medical Center
Excessive Physical Exercise, Unspecified
The Effects of a Dietary Supplement on Exercise Performance in Healthy Older Adults"
Human exercise capacity decreases with aging. One explanation may be that blood vessels stiffen with age and release less of a compound called nitric oxide (NO).
- Trial name
- NCT01073332
- Testing
- Arginine antioxidant supplements
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pre-Eclampsia
Glomerular Injury of Preeclampsia
Pre-eclampsia complicates 7 - 10% of pregnancies and constitutes a leading cause of fetal growth retardation and premature birth, as well as infant and maternal morbidity and mortality.
- Trial name
- NCT00275158
- Testing
- L-Arginine Supplementation
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Myocardial Dysfunction
Effects of L-arginine on Myocardial Energetic Efficiency and Global Longitudinal Strain
The study is designed to evaluate the effects of L-arginine on myocardial structure and function and circulating microRNAs in patients with arterial hypertension.
- Trial name
- BIOCARDIO (NCT04626375)
- Testing
- Bioarginine
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federico II University