Clinical trials: LUMBAR STENOSIS
Lumbar Spinal Stenosis
MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
This is a multi-center, prospective, patient outcomes assessment of Minimally Invasive Lumbar Decompression with the Mild® devices in patients with symptomatic central canal spinal stenosis.
- Trial name
- NCT01082159
- Testing
- lumbar decompression
- Where
- 8 sites in United States
- Volunteers
- 55 people
- Sponsor
- Vertos Medical, Inc.
Lumbar Spinal Stenosis, Surgery
Percutaneous Endoscopic Decompression for Lumbar Canal Stenosis
Lumbar spinal stenosis (LSS) is the most common spinal degenerative disease. For conservative treatment failure, open lumbar decompression and fusion surgery is the main surgical treatment.
- Trial name
- NCT04254757
- Testing
- Two different treatment
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking University Third Hospital
Lumbar Spinal Stenosis
Effectiveness and Safety of Pharmacopuncture Therapy for Patients with Lumbar Spinal Stenosis
This is 1:1 pragmatic randomized controlled trials in a parallel-grouped, multi-centered design that investigated pharmacopuncture therapy for patients with lumbar spinal stenosis, compared to the conservative treatments…
- Trial name
- NCT05242497
- Testing
- pharmacopuncture, conservative treatments (including physiotherapy)
- Where
- 7 sites in South Korea
- Volunteers
- 98 people
- Sponsor
- Jaseng Medical Foundation
Spinal Stenosis, Low Back Pain
Effects of Maitland and Mulligan Spinal Mobilizations Along With Canal Enlargement Exercises in Lumbar Spinal Stenosis
This randomised controlled trial will evaluate the comparative effects of Maitland versus Mulligan spinal mobilization techniques, when combined with canal enlargement exercises, in patients with lumbar spinal stenosis (LSS).
- Trial name
- NCT07080073
- Testing
- Maitland Mobilization Group, Mulligan Mobilization Group
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Cardiac Amyloidosis, Spinal Stenosis
Prevalence of Cardiac Amyloidosis Among Patients With a History of Lumbar Spinal Stenosis.
The study investigates the prevalence of cardiac amyloidosis among patients with a history of lumbar spinal stenosis within the last ten years in the region of central Denmark.
- Trial name
- CASS-I (NCT05701410)
- Testing
- DPD scintigraphy
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Steen Hvitfeldt Poulsen
Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome
Efficacy of Pregabalin in Patients With Radicular Pain
The purpose of this study is to evaluate whether pregabalin is effective in reducing the pain in patients who present with radicular pain due to a herniated disc, spinal stenosis or failed back surgery syndrome.
- Conditions
- Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome, Spinal Stenosis, Herniated Disc
- Trial name
- NCT00908375
- Testing
- Pregabalin, Sugar Pill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Northwestern University
Spinal Stenosis
MIS-D Versus MIS-TLIF for the Treatment of Lumbar Spinal Stenosis
The purpose of this study is to evaluate the effectiveness of two minimal invasive spine surgery, minimally invasive spinal decompression (MIS-D) and minimally invasive spinal decompression and fusion (MIS-TLIF), for patients…
- Trial name
- NCT04318795
- Testing
- minimally invasive spinal decompression (MIS-D), minimally invasive spinal decompression and fusion (MIS-TLIF)
- Volunteers
- 80 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Lumbar Spinal Stenosis
Assessment of Gait Parameters and Their Impact on Postoperative Recovery in Patients With Lumbar Spinal Stenosis
The objective is to observe the evolution of walking parameters during the surgery process and find which of all calculated walking parameters represent the best indicators of functional disabilities and postoperative recovery…
- Trial name
- NCT04250753
- Testing
- Walking task
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Université du Québec à Trois-Rivières
Lumbar Spinal Stenosis, Erector Spinae Plane Block
Erector Spinae Plane Block After Lumbar Spinal Stenosis Surgery
Lumbar spinae stenosis surgery is a frequent intervention resulting in important postoperative pain. Management of this postoperative pain is thus important. Different pain management therapies exist.
- Trial name
- NCT04403360
- Testing
- ESPB, Local infiltration by the surgeon
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Clinique Saint Pierre Ottignies
Degenerative Lumbar Spinal Stenosis
TCM Conservative Treatment for the Degenerative Lumbar Spinal Stenosis
Lumbar degenerative disease is a common disease develops into degenerative lumbar spinal stenosis(DLSS)in the elderly and eventually.
- Trial name
- NCT05273346
- Testing
- Traditional Chinese medicinal ointment, Acupotomy, Cupping therapy with bamboo cup
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Beijing University of Chinese Medicine
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Dorsal Root Ganglion Intervention Treatments
This study applies 3D-printed customized guide plate in assisting the accurate puncture in transforaminal epidural steroid injection (TFESI) combined with pulsed radiofrequency (PRF) treatment.
- Trial name
- NCT05403775
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Degenerative Disc Disease, Spondylolisthesis
Study of 3 Doses of NeoFuse Combined With MasterGraft Granules in Subjects Requiring Posterolateral Lumbar Fusion (PLF)
This is a first-in-human, dose escalation clinical study to evaluate the feasibility, safety, and tolerability of 3 different doses of immunoselected, culture-expanded, nucleated, allogeneic MPCs (NeoFuse) when combined with…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT00549913
- Testing
- NeoFuse, posterolateral spinal fusion with instrumentation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mesoblast, Ltd.
ATTR Amyloidosis, Cardiopathy
Orthopaedic Specimen Pathology and Early Diagnosis of ATTR Cardiopathy (ATTR-ORTHO)
The goal of this observational study is to learn about the frequency of ATTR amyloid, cardiac involvement and associated features, in 150 patients aged 50 or more years, and operated for an idiopathic carpal tunnel syndrome…
- Conditions
- ATTR Amyloidosis, Cardiopathy, Carpal Tunnel Syndrome, Lumbar Spine Stenosis
- Trial name
- ATTR-ORTHO (NCT06367842)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Institut Mutualiste Montsouris
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Preventive Effect of Limited Decompression on Adjacent Segment Following Posterior Lumbar Interbody Fusion
This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for degenerative disease are prospectively enrolled and followed.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degeneration Spine
- Trial name
- NCT04469387
- Testing
- Limited decompressions at adjacent segment with asymptomatic pre-existing spinal canal stenosis, Responsible segments fused
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Lumbar Spinal Stenosis (LSS)
Association Between Lumbar Muscle Atrophy, Sagittal Pelvic Alignment and Stenosis Grade in Patients With Degenerative Lumbar Spinal Stenosis
This study is to evaluate the correlation between muscle atrophy (MA), sagittal alignment, and stenosis degree in patients with lumbar spinal Stenosis (LSS).
- Trial name
- AtrophyLSS (NCT04444739)
- Testing
- radiographic data collection
- Where
- Switzerland
- Volunteers
- 165 people
- Sponsor
- University Hospital, Basel, Switzerland
Spinal Stenosis
The Impact of Spinal Manipulation on Leg Movement in Lumbar Spinal Stenosis Patients
The objectives of the proposed research are to quantify the impact on motor performance of a single SM intervention on surgical waitlist patients with degenerative Lumbar Spinal Stenosis (LSS) using a recently established lower…
- Trial name
- NCT02118103
- Testing
- Spinal Manipulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Lumbar Spinal Stenosis
The Effectiveness and Safety of Dong-A Opalmon® Tablet in Patients With Acquired Lumbar Spinal Stenosis
This study is to evaluate the Effectiveness and Safety of Dong-A Opalmon® Tablet in Patients With Acquired Lumbar Spinal Stenosis
- Trial name
- NCT06654856
- Where
- South Korea
- Volunteers
- 107 people
- Sponsor
- Dong-A ST Co., Ltd.
Degenerative Lumbar Spondylolisthesis
Long-term Reoperations After Lumbar Spinal Stenosis Surgery
Severe and persisting pain and disability due to a degenerative narrowing of the spinal canal, lumbar spinal stenosis, can be operated with a simple surgical decompression.
- Trial name
- NCT06407063
- Testing
- Micro-decompression alone, Decompression and instrumented fusion
- Where
- Norway
- Volunteers
- 794 people
- Sponsor
- University Hospital of North Norway
Lumbar Spinal Stenosis
Vertos Mild - Post Market Patient Outcomes
This is a single-center study evaluating the outcomes of patients with painful lumbar spinal stenosis who were treated with the mild procedure (minimally invasive lumbar decompression.
- Trial name
- NCT01076244
- Testing
- Minimally Invasive Lumbar Decompression
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Center for Pain Relief, Inc.
Degenerative Disc Disease, Spinal Stenosis
Effectiveness of Lumbar Fusion When NanOss Bioactive Is Used With Posterolateral Gutter Fusions
Spine fusion is one of the most common procedures performed in spinal surgery. Several surgical techniques can achieve a solid union, but the intertransverse posterolateral fusion (PLF) is the most widely used.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT01452516
- Testing
- nanOss Bioactive Bone void filler, Interbody FCage
- Where
- 7 sites in United States
- Volunteers
- 28 people
- Sponsor
- Pioneer Surgical Technology, Inc.