Clinical trials: LUTS(Lower Urinary Tract Symptoms)
LUTS(Lower Urinary Tract Symptoms), Benign Prostatic Hyperplasia
The PK Study of the JLP-1207 and Solifenacin/Tamsulosin in Healthy Male Volunteers.
The purpose of this study is to investigate and compare the pharmacokinetic characteristics and safety/tolerability between JLP-1207(Solifenacin/Tamsulosin 5mg/0.2mg)and co-administration of Solifenacin and Tamsulosin between…
- Conditions
- LUTS(Lower Urinary Tract Symptoms), Benign Prostatic Hyperplasia, Overactive Bladder
- Trial name
- NCT02494349
- Testing
- JLP-1207, Solifenacin 5mg+Tamsulosin 0.2mg
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Benign Prostatic Hyperplasia, Prostatic Diseases
European Registry for Transperineal Laser Ablation of Prostate (TPLA) for Lower Urinary Tract Symptoms
The goal of this observational study is to assess mid- and long-term effectiveness of Transperineal Laser Ablation of Prostate (TPLA) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic obstruction…
- Trial name
- NCT06564415
- Testing
- Transperineal Laser Ablation of Prostate
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- University of Florence
Voiding Disorders
Brain Imaging in Men With Lower Urinary Tract Symptoms
Benign Prostatic Hyperplasia (BPH) affects the storage and voiding phases of the micturition cycle. Lower urinary tract symptoms (LUTS) refers to storage symptoms such as urinary frequency, urgency, urge urinary incontinence and…
- Trial name
- NCT03991429
- Testing
- Simultaneous functional MRI and urodynamic studies, Questionnaires, Post Void Residual (PVR), Uroflow and Bladder Diary
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Methodist Hospital Research Institute
Prostatic Hyperplasia, Benign Prostatic Hyperplasia (BPH)
Prostate Artery Embolization (PAE) for Treatment of Benign Prostatic Hyperplasia
The purpose of this project is to evaluate the safety, efficacy, and feasibility of performing prostatic artery embolization (PAE) using endovascular techniques and particle embolics in men suffering from lower urinary tract…
- Conditions
- Prostatic Hyperplasia, Benign Prostatic Hyperplasia (BPH), Prostatism, Lower Urinary Tract Symptoms (LUTS)
- Trial name
- NCT02592473
- Testing
- Embozene Microspheres
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
BPH (Benign Prostatic Hyperplasia)
Prospective Post Market Clinical Registry for the Zenflow Spring System - A Minimally Invasive Treatment for LUTS Associated With BPH Spring System Registry
The purpose of this registry is to collect information on how the Zenflow Spring System works in everyday medical practice. The registry will track how the Spring System performs during the implant procedure, and at follow-up…
- Trial name
- NCT07538622
- Testing
- Zenflow Spring System
- Where
- 8 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zenflow, Inc.
Benign Prostatic Hyperplasia
A Study of Tadalafil (LY450190) in Participants With Lower Urinary Tract Symptoms (LUTS) Suggestive of Benign Prostatic Hyperplasia LUTS (BPH-LUTS).
The main purpose of this study is to evaluate the safety and efficacy of the study drug known as tadalafil in participants with benign prostatic hyperplasia who are being treated with an alpha1 blocker.
- Trial name
- NCT02431754
- Testing
- Tadalafil, Alpha1 Blocker
- Where
- 9 sites in Japan
- Volunteers
- 171 people
- Sponsor
- Eli Lilly and Company
BPH With Symptomatic Lower Urinary Tract Symptoms
ProVIDE II Bridging Study
The purpose of the ProVIDE II Bridging Study is to evaluate the performance of the Generation II delivery system when deploying the ProVee expander in subjects with symptomatic urinary obstruction secondary to BPH.
- Trial name
- NCT06236802
- Testing
- ProVee device
- Where
- 8 sites in United States, Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ProVerum Medical
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Evaluation of Symptom-specific Goal Achievement
Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) consists of a constellation of symptoms (including voiding, storage, and post-micturition).
- Trial name
- NCT00836823
- Testing
- Alfuzosin
- Where
- 2 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Benign Prostatic Hyperplasia (BPH)
Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue II
Single-arm, interventional pivotal clinical trial collecting patient data from use of the AQUABEAM System, a personalized image-guided waterjet resection system that utilizes a high-velocity saline stream to resect and remove…
- Trial name
- WATERII (NCT03123250)
- Testing
- Aquablation
- Where
- 16 sites in United States, Canada
- Volunteers
- 101 people
- Sponsor
- PROCEPT BioRobotics
Benign Prostate Hyperplasia
Safety, Efficacy, and Short-Term Outcomes of Rezūm Water Vapor Thermal Therapy for Benign Prostatic Hyperplasia Under Local Anesthesia With Intravenous Sedation: A Single-Center Retrospective Study of 129 Patients in the Kurdistan Region of Iraq
This single-center retrospective study evaluates the safety, feasibility, and short-term clinical outcomes of Rezūm water vapor thermal therapy (WVTT) for the treatment of lower urinary tract symptoms (LUTS) secondary to benign…
- Trial name
- NCT07507591
- Testing
- Rezum Water Vapor Thermal Therapy
- Where
- Iraq
- Volunteers
- 129 people
- Sponsor
- ALI KAMAL M. SAMI
Quality of Life, Sexual Dysfunction
Benign Prostate Surgery and QOL and Sexual Function
Rationale: A variety of surgical techniques have been described for surgical treatment of male LUTS because of BPH, which has different outcomes and may result in adverse events regarding ejaculatory function and erection…
- Conditions
- Quality of Life, Sexual Dysfunction, Ejaculatory Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- BEPS (NCT05826691)
- Testing
- Monopolar / Bipolar Transurethral resection of prostate (TURP), photovaporisation (PVP), Plasmakinetic (PK), Holmium laser enucleation of the prostate (HOLEP) or open prostatectomy (OP)).
- Where
- Turkey (Türkiye)
- Volunteers
- 1,200 people
- Sponsor
- Istanbul Medipol University Hospital
HIV Seropositivity, Lower Urinary Tract Symptoms
Lower Urinary Tract Symptoms in Males Living With HIV
The primary aim of this study is to learn whether the frequency of lower urinary tract symptoms differ between the males with seronegativity for HIV and males living with HIV.
- Trial name
- NCT05964803
- Testing
- Questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Koç University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Study of Light-Activated Talaporfin Sodium in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)
This is a phase 2 study to evaluate the safety and effectiveness of light-activated talaporfin sodium in patients with LUTS due to benign prostatic hyperplasia (BPH).
- Trial name
- NCT00918034
- Testing
- talaporfin sodium, Transurethral illumination with light emitting diodes, Placement
- Where
- 8 sites in Australia, New Zealand
- Volunteers
- 21 people
- Sponsor
- Light Sciences Oncology
BPH, LUTS(Lower Urinary Tract Symptoms)
Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients with BPH.
Benign prostatic hyperplasia (BPH) is one of the most prevalent human diseases and a major cause of lower urinary tract symptoms (LUTS).
- Trial name
- TryptoBPH (NCT05401032)
- Testing
- Tamsulosin, 5-hidroxitriptophan
- Where
- Portugal
- Volunteers
- 70 people
- Sponsor
- Clinical Academic Center (2CA-Braga)
Lower Urinary Tract Symptoms
Prevalence and Risk Factor of NP in Women With LUTS
The knowledge of prevalence and risk factors of nocturnal polyuria might be important for the treatment of women with lower urinary tract symptoms (LUTS).
- Trial name
- NCT04104100
- Volunteers
- 3,000 people
- Sponsor
- National Taiwan University Hospital
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Evaluation of the Safety, Tolerability, and Efficacy of the Omega System for the Treatment of LUTS Due to BPH
This is a prospective, two-stage, multi-center, pilot clinical study to evaluate the safety/tolerability/efficacy of the Omega System device.
- Trial name
- Omega (NCT05757687)
- Testing
- Omega device
- Where
- 5 sites in Georgia
- Volunteers
- 11 people
- Sponsor
- ProArc Medical
Bladder Outlet Obstruction
Antimuscarinics as the First-line Treatment for Male With IPSS-V/S≤1
This study is a prospective randomized, open label, controlled, double arm, post-marketing study to compare the treatment efficacy of first-line antimuscarinics and α-blockers monotherapy for men with moderate to severe lower…
- Trial name
- NCT01661621
- Testing
- Detrusitol 4 mg QD, Doxazosin 4 mg QD
- Where
- Taiwan
- Volunteers
- 395 people
- Sponsor
- Buddhist Tzu Chi General Hospital
BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms
RT-310 Dose Escalation BPH Study
RT-310, a novel implant, is intended to minimally invasive treat locally the prostate gland for the management of prostate disease, while minimizing side-effects.
- Trial name
- NCT06136819
- Testing
- RT-310
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 20 people
- Sponsor
- Resurge Therapeutics Inc.
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Benign Prostatic Hyperplasia (BPH) Mobile Application Pilot Study
This study assesses the feasibility, and acceptability of a (mobile) application for men presenting at their physician's office with LUTS/BPH; starting with medical therapy and naïve for treatment.
- Trial name
- NCT03228485
- Testing
- MyBPH Care mobile app
- Where
- 5 sites in Greece, Italy and 3 more
- Volunteers
- 200 people
- Sponsor
- Société Internationale d'Urologie
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
Selective Median Lobe Surgery Outcomes Study
This prospective multicenter observational cohort study will evaluate clinical outcomes after selective median lobe transurethral surgery for benign prostatic obstruction.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH), Benign Prostatic Obstruction, Urinary Retention
- Trial name
- UNVEIL-BPO (NCT07699718)
- Testing
- Selective Median Lobe TURP, Selective Median Lobe HoLEP/AEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Necmettin Erbakan University