Clinical trials: LUTS(Lower Urinary Tract Symptoms)
Quality of Life, Sexual Dysfunction
Benign Prostate Surgery and QOL and Sexual Function
Rationale: A variety of surgical techniques have been described for surgical treatment of male LUTS because of BPH, which has different outcomes and may result in adverse events regarding ejaculatory function and erection…
- Conditions
- Quality of Life, Sexual Dysfunction, Ejaculatory Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- BEPS (NCT05826691)
- Testing
- Monopolar / Bipolar Transurethral resection of prostate (TURP), photovaporisation (PVP), Plasmakinetic (PK), Holmium laser enucleation of the prostate (HOLEP) or open prostatectomy (OP)).
- Where
- Turkey (Türkiye)
- Volunteers
- 1,200 people
- Sponsor
- Istanbul Medipol University Hospital
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Registry of MIUS for Benign Prostatic Obstruction
This national, multicenter, prospective registry aims to collect standardized perioperative and follow-up data on patients undergoing minimally invasive surgical management for benign prostatic obstruction (BPO) in Turkey.
- Trial name
- ReMIUS-BPO (NCT07159165)
- Testing
- Minimally invasive surgical treatment for benign prostatic obstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Ondokuz Mayıs University
Lower Urinary Tract Symptoms, Hypertension
Effect of Amlodipine Monotherapy or Combined With Terazosin on Lower Urinary Tract Symptoms and Hypertension
The aim of this study was to investigate the efficacy and safety of low dose amlodipine alone, or combined with low dose terazosin in male patients with both lower urinary tract symptoms and hypertension.
- Trial name
- NCT00693199
- Testing
- amlodipine, terazosin, amlodipine plus terazosin
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Anhui Medical University
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Effect of 12 Weeks Treatment With Tadalafil vs Placebo on Lower Urinary Tract Symptoms
At present time several preclinical and clinical study have demonstrated the safety and efficacy of PDE5 (phosphodiesterase type 5)-inhibitors for LUTS/BPH (lower urinary tract symptoms/benign prostatic hyperplasia) patients with…
- Trial name
- NCT02252367
- Testing
- Tadalafil
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Florence
Developmental Coordination Disorder, Lower Urinary Tract Symptoms
Impaired Toilet Training, LUTS and Bowel Dysfunction in Children With DCD
This cross-sectional case-control study aimed to determine whether there is a significant difference in the prevalence of impaired toilet training, LUTS, and functional bowel problems among children diagnosed with DCD and…
- Conditions
- Developmental Coordination Disorder, Lower Urinary Tract Symptoms, Bowel Dysfunction
- Trial name
- NCT06311110
- Testing
- Vancouver symptom score for dysfunctional elimination symptoms Questionnaire, Developmental Coordination Disorder Questionnaire, Questionnaire concerning impaired toilettraining and comorbities
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Lower Urinary Tract Symptoms
Double j Stent Related Symptoms
In urology, ureteral stents are used to treat obstructive diseases. Hematuria (54%), fever, discomfort, and lower urinary system symptoms are the predominant symptoms related to ureteral stent.
- Trial name
- NCT07447518
- Testing
- Tadalafil 5mg, solidosin, Solfenacin
- Where
- Egypt
- Volunteers
- 535 people
- Sponsor
- Kafrelsheikh University
Lower Urinary Tract Symptoms
Validation of Bladder Health Instrument for Evaluation in Women
The Prevention of Lower Urinary Symptoms (PLUS) Research Consortium is working to optimize prevention of lower urinary tract symptoms (LUTS) in women and adolescent females across their life spans.
- Trial name
- VIEW (NCT04016298)
- Where
- 8 sites in United States
- Volunteers
- 1,222 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hyperplasia
Efficacy And Safety Study Of Naftopidil to Patients Treatment With LUTS
The purpose of this study is to evaluate the effectiveness and safety of Naftopidil and Tamsulosin in the treatment of lower urinary tract symptoms through a comparative study of patients with benign prostatic hyperplasia.
- Trial name
- NCT01203371
- Testing
- Naftopidil, Tamsulosin
- Where
- Brazil
- Sponsor
- Apsen Farmaceutica S.A.
Benign Prostatic Hyperplasia, Prostatic Diseases
European Registry for Transperineal Laser Ablation of Prostate (TPLA) for Lower Urinary Tract Symptoms
The goal of this observational study is to assess mid- and long-term effectiveness of Transperineal Laser Ablation of Prostate (TPLA) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic obstruction…
- Trial name
- NCT06564415
- Testing
- Transperineal Laser Ablation of Prostate
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- University of Florence
Prostatic Hyperplasia
The Impact of Alna® Ocas® on Nocturia in Patients With Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (LUTS/BPH)
Study to assess efficacy, tolerability and safety parameters of a three month ALNA®OCAS® -treatment with special respect to nocturia
- Trial name
- NCT02245542
- Testing
- ALNA®OCAS®
- Volunteers
- 5,775 people
- Sponsor
- Boehringer Ingelheim
Benign Prostate Hypertrophy(BPH), LUTS(Lower Urinary Tract Symptoms)
MISTER Study: Minimally Invasive Steam Therapy - Russian Effectiveness Registry
Rezūm is a minimally invasive procedure that uses water vapor (steam) to treat urinary symptoms caused by an enlarged prostate (benign prostatic hyperplasia, BPH).
- Trial name
- MISTER (NCT07723378)
- Testing
- Rezūm
- Where
- Russia
- Volunteers
- 1,400 people
- Sponsor
- Sechenov University
Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Clinical Trial on the Effectiveness of TUMT Compared to PAE in Reducing Severe LUTS in Men with BPH
The TUMT-PAE-1 trial is a randomised clinical trial aiming to compare the effectiveness of transurethral microwave thermotherapy (TUMT) with prostatic artery embolisation (PAE) in reducing urinary symptoms caused by prostate…
- Trial name
- TUMT-PAE-1 (NCT05686525)
- Testing
- Transurethral Microwave Thermotherapy, Prostate Artery Embolisation
- Where
- 3 sites in Denmark
- Volunteers
- 220 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prostatic Neoplasms, Prostate Disease
Single Dose Versus Double Dose Tamsulosin in Management of Moderate and Severe LUTS Due to BPH
Single dose versus double dose tamsulosin in Management of Moderate and severe lower urinary tract symptoms due to benign prostatic hyperplasia
- Conditions
- Prostatic Neoplasms, Prostate Disease, Prostate Obstruction, Prostate Hypertrophy
- Trial name
- NCT05834270
- Testing
- Single dose tamsulosin 0.4mg, Double dose tamsulosin 0.4mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Benign Prostatic Hyperplasia, Prostate Cancer
Effects of Alpha Blockers on Prostate-specific Antigen (PSA) Change in Men With Lower Urinary Tract Symptoms (LUTS)
The correlation between the change of serum prostate-specific antigen (PSA) or PSA velocity (PSAV) and severity of lower urinary tract symptoms (LUTS) has been poorly understood.
- Trial name
- NCT01250483
- Testing
- PSA measurement, uroflowmetry, IPSS, transrectal ultrasonography
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Lower Urinary Tract Symptoms
Reliability of Home Uroflowmetery Using a Disposable Digital Device
The FloRite™ device is a disposable urine flow meter, indicated for use in a home setting. The device provides Urofowmetry measurements, similar to clinic's measurements.
- Trial name
- NCT02026674
- Testing
- FloRite
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Flometrica Ltd.
Male, Stroke
Pelvic Floor Muscle Training(PFMT) on Lower Urinary Tract Symptoms (LUTS) in Men With Stroke
The aim of this study is to evaluate the effect of pelvic floor muscle training (PFMT) on Lower Urinary Tract Symptoms (LUTS) in men after stroke.
- Conditions
- Male, Stroke, Urinary Incontinence
- Trial name
- NCT01042249
- Testing
- Pelvic Floor Muscle training
- Where
- Denmark
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Lower Urinary Tract Symptoms (LUTS)
RCT on Running Water Sound During Urodynamic
This study aims to see if listening to recorded running water sounds during a bladder function test (urodynamic study) helps patients feel calmer and makes it easier for them to empty their bladder during the test.
- Trial name
- NCT07451548
- Testing
- Auditory intervention with running water sound
- Where
- 2 sites in Hong Kong
- Volunteers
- 240 people
- Sponsor
- Princess Margaret Hospital, Hong Kong
Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms
Anesthesia Type and HoLEP Outcomes: A Multi-Center Study
1. What is this study about, and why is it required? The goal of this observational study is to learn if anesthesia type (e.g., general anesthesia, spinal anesthesia) affects the safety and efficiency of HoLEP surgery.
- Trial name
- NCT07585552
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Ondokuz Mayıs University
Lower Urinary Tract Symptoms
Electronic Method for Recording Lower Urinary Tract Symptoms
Urinary diaries have proven to be beneficial in assessing lower urinary tract symptoms (LUTS), however they have not achieved widespread acceptance.
- Trial name
- NCT02060136
- Where
- Czechia
- Volunteers
- 29 people
- Sponsor
- University Hospital Ostrava
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Prostatic Artery Embolization for the Treatment of Symptomatic Benign Prostatic Hyperplasia (BPH)
This is a single center, prospective, investigational study to evaluate the safety and efficacy of prostatic artery embolization (PAE) for the treatment of moderate to severe lower urinary tract symptoms (LUTS) due to benign…
- Trial name
- NCT04563221
- Testing
- Prostatic artery embolization
- Where
- United States
- Sponsor
- Andrew Picel