Clinical trials: LVAD (Left Ventricular Assist Device)
Cardiac Rehabilitation, Heart Failure
Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery
The RECOVER study, titled Cardiac Rehabilitation Cohort at the Medicine Campus Davos for Exploration of Recovery, is a prospective, non-interventional, monocentric cohort study conducted at the Hochgebirgsklinik Davos.
- Conditions
- Cardiac Rehabilitation, Heart Failure, Cardiac Arrest (CA), ACS (Acute Coronary Syndrome)
- Trial name
- RECOVER (NCT07096973)
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Hochgebirgsklinik Davos
LVAD (Left Ventricular Assist Device) Thrombosis, Heart Failure
SWITCH: Apixaban vs Vitamin K in HM3
This study is being done to learn the safety and efficacy of a new anticoagulant therapy with apixaban as compared to warfarin to prevent thrombotic events while protecting from bleeding complications in patients with advanced…
- Conditions
- LVAD (Left Ventricular Assist Device) Thrombosis, Heart Failure, Bleeding, Thrombosis; Artery
- Trial name
- NCT07471139
- Testing
- Warfarin, Apixaban
- Volunteers
- 460 people
- Sponsor
- Columbia University
LVAD Caregivers, LVAD (Left Ventricular Assist Device)
Compassion Strikes Back
Research has shown that LVAD patients and their caregivers typically experience increased mental health concerns and decreased quality of life following LVAD implantation and hospital discharge.
- Conditions
- LVAD Caregivers, LVAD (Left Ventricular Assist Device), Quality of Life (QOL), Self-Compassion
- Trial name
- NCT06988995
- Testing
- Information, Meeting
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
LVAD (Left Ventricular Assist Device) Thrombosis, LVAD
STudy of Aspirin Removal in Patients Supported by the Fully Magnetically Levitated CH-VAD Pump
This multi-center, prospective, randomized, double-blinded, placebo-controlled study aims to investigate whether withdrawal of aspirin from the antithrombotic regimen in patients supported with the CH-VAD pump is non-inferior to…
- Conditions
- LVAD (Left Ventricular Assist Device) Thrombosis, LVAD, LVAD (Left Ventricular Assist Device), LVAD-related GI Bleed
- Trial name
- STAR (NCT07644247)
- Testing
- Warfarin (INR 2-3) with aspirin
- Volunteers
- 370 people
- Sponsor
- China National Center for Cardiovascular Diseases
LVAD (Left Ventricular Assist Device)
Feasibility and Clinical Utility of Ambulatory Ultraslow Deflation Sphygmomanometers in LVAD Recipients - easiSLOW-LVAD Pilot
Prospective, single-arm feasibility study will evaluate the use of an ultraslow deflation automated sphygmomanometer (Terumo Elemano 2) for home BP monitoring in patients with continuous-flow LVADs.
- Trial name
- easiSLOW-LVAD (NCT07633561)
- Testing
- Ultraslow deflation cuff
- Volunteers
- 50 people
- Sponsor
- University of Florida
Heart Failure, Advanced Heart Failure
REACTION-VAD Trial: Remote Exercise Training Via Telemedicine in Patients With Long-Term Ventricular Assist Devices
Current international guidelines recommend that patients with a heart pump (left ventricular assist device, LVAD) participate in supervised exercise cardiac rehabilitation programs.
- Conditions
- Heart Failure, Advanced Heart Failure, Left Ventricular Assist Device, LVAD
- Trial name
- REACTION-VAD (NCT07611188)
- Testing
- Remote Physical Conditioning Program (Telerehabilitation), Usual care. No Remote Monitoring.
- Where
- 10 sites in Spain
- Volunteers
- 78 people
- Sponsor
- Puerta de Hierro University Hospital
LVAD (Left Ventricular Assist Device) Driveline Infection
A Silver Lining in the VAD Sky
The investigators propose to conduct a prospective randomized trail (RCT) of a driveline management protocol. The study will be initiated at UCSF from January 1st 2022 to December 31st 2022 as a pilot to be extended to other…
- Trial name
- LVAD-SilverD (NCT05163392)
- Testing
- Silverlon, Control
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
LVAD (Left Ventricular Assist Device) Driveline Infection
Non-invasive Detection of Driveline Infections in Patients with a Left Ventricular Assist Device
The aim of this single center observational study is to determine the feasibility of using non-invasive imaging methods, including smartphone photography and infrared thermography, for detecting of DLIs in LVAD patients in terms…
- Trial name
- DRIVE-ID (NCT06867887)
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Erasmus Medical Center
LVAD (Left Ventricular Assist Device) Driveline Infection
Effect of Cardiac Resynchronization Therapy (CRT) on Left Ventricular Assist Device (LVAD) Function
Certain patients with congestive heart failure are treated both by implantation of an LVAD, as well as implantation with a biventricular pacemaker.
- Trial name
- NCT04153786
- Testing
- Temporary changes in an already-implanted medical device (biventricular pacemaker)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Davis
LVAD (Left Ventricular Assist Device) Thrombosis
DOT HeartMate 3 Study
A prospective, single-center, randomized controlled trial of the feasibility and safety of apixaban in HeartMate 3 patients.
- Trial name
- NCT04974684
- Testing
- HeartMate 3, Apixaban
- Where
- Czechia
- Volunteers
- 45 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Ventricular Tachycardia, End-stage Heart Failure
Ventricular Tachycardia Ablation in LVAD Patients
The CHANNELED-Registry is a multicenter retrospective study to (1) systematically assess the mechanism and origin of ventricular tachycardia in patients with end-stage heart failure carrying an left ventricular assist device…
- Conditions
- Ventricular Tachycardia, End-stage Heart Failure, Ventricular Arrythmia, LVAD (Left Ventricular Assist Device)
- Trial name
- CHANNELED (NCT06063811)
- Testing
- Ablation
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Köln
Left Ventricular Assist Device, Heart Failure
Pulse Wave Analysis in Advanced Heart Failure
A comparison of pulse wave characteristics, as measured by peripheral tonometry, in pre and post Left Ventricular Assist Device (LVAD) patients.
- Conditions
- Left Ventricular Assist Device, Heart Failure, Intra-aortic Balloon Pump, LVAD Clot
- Trial name
- PWA-HF (NCT01642927)
- Where
- United States
- Sponsor
- University of Minnesota
Left Sided Heart Failure, Left Ventricular Assist Device
Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial
This study evaluates two different methods for monitoring a patient's anti-clotting [heparin] therapy after they receive a heart pump implant [left ventricular assist device -LVAD].
- Conditions
- Left Sided Heart Failure, Left Ventricular Assist Device, Anticoagulant Therapy, Gastro Intestinal Bleeding
- Trial name
- VAD-ANTIX (NCT03143569)
- Testing
- aPTT guided heparin management, Anti-factor Xa guided heparin management
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine