Clinical trials: Labor, Obstetric
Preterm Labor
Nanovectors to Prevent Placental Passage of Tocolytic Agents
The purpose of the study is to find out whether indomethacin encapsulated within a nanovector can stop contractions in pregnant human uterine tissue. Preterm delivery is a major contributor to newborn deaths.
- Trial name
- NCT02199756
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Labor Complications
Randomized Control Trial of Second Stage of Labor
The hypothesis of this study is that extending the second stage of labor beyond current American College of Obstetricians and Gynecologists suggestions can reduce the cesarean delivery rate.
- Trial name
- NCT02101515
- Testing
- Length of Second Stage
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Preterm Labour, Preterm Birth
Evaluation of a Novel Diagnostic Kit for the Detection of Placental Alpha-Microglobulin-1 in the Prediction of Preterm Birth
This is a prospective observational trial that will enroll pregnant women between 24 and 36 6/7 weeks of gestation that present with signs and symptom of preterm labor with clinically intact membranes and cervical dilatation ≤ 3…
- Trial name
- NCT02092688
- Testing
- novel kit for the detection of PAMG-1
- Where
- Switzerland
- Volunteers
- 126 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Labor, Premature, Preterm Premature Rupture of the Membranes
N-acetylcysteine in Intra-amniotic Infection/Inflammation
The aim of the study is to determine if N-acetylcysteine (a potent free radical scavenger) prevents the occurrence of adverse neonatal outcomes in preterm deliveries complicated by infection associated with preterm labor or…
- Conditions
- Labor, Premature, Preterm Premature Rupture of the Membranes, Infection, Inflammation
- Trial name
- NCT00397735
- Testing
- amniocentesis
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Ohio State University
Obstetric Pain
Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Cesarean delivery is one of the most common surgical procedures, performed at an increasingly high rate. It is associated with intense postoperative pain that may hamper the rehabilitation process and interfere with patient…
- Trial name
- NCT03502642
- Testing
- wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain), Spinal Anesthesia, intrathecal morphine
- Where
- Lebanon
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Preterm Birth, Preterm Labor
Correlation Between Maternal Vitamin D Level And Preterm Birth
Assessment of correlation between vitamin D level and prevalence of preterm births remains limited. The exact role of vitamin D in preterm birth has not yet been clearly defined ,where some studies showed vitamin D deficiency…
- Conditions
- Preterm Birth, Preterm Labor, Vitamin D Deficiency
- Trial name
- NCT03638037
- Testing
- Vitamin D measurement
- Where
- Egypt
- Volunteers
- 138 people
- Sponsor
- Ain Shams Maternity Hospital
Preterm Contractions
Uterine Contractions Under Blue Light
The objective in the current study is to test the hypothesis that nocturnal uterine contractions in preterm women can be suppressed by brief ocular exposure to blue light.The Olcese lab at Florida State University identified a…
- Trial name
- NCT03691740
- Testing
- Ocular light
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obstetric Labor, Premature
Indomethacin Versus Nifedipine for Preterm Labor Tocolysis
Indomethacin and Nifedipine are commonly used medications for treatment of pre term labor. This study will compare the efficacy and adverse outcomes of oral nifedipine versus oral indomethacin for preterm labor tocolysis in an…
- Trial name
- NCT00486824
- Testing
- Indomethacin, Nifedipine
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Obstetric Pain
Bupivacaine Verus Pethidine for Post Cesarean Section Pain Relief
The aim of this study is to compare between the effect of wound infiltration with bupivacaine or pethidine for post cesarean section pain relief.
- Trial name
- NCT03652116
- Testing
- Wound infiltration by Bupivacaine, Wound infiltration by Pethidine
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Obstetric Pain
The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section
The transversus abdominis plane block (TAP block) has effect to postoperative analgesia for cesarean section with spinal anesthesia but it was limited for cesarean section with general anesthesia.
- Trial name
- TAP (NCT03634111)
- Testing
- TAP block, Morphine, Ropivacaine
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Preterm Labor
UTEROCERVİCAL ANGLE MEASUREMENT IN SPONTANEOUS PRETERM BIRTH (UAMSPB)
İn this study Study; Between August 2018 and August 2019, the Ministry of Health, Medeniyet University, Göztepe Training and Research Hospital, Gynecology and Obstetrics Clinic Will be Included for Routine Control Purposes…
- Trial name
- UAMSPB (NCT03623685)
- Testing
- measurement of uterocervical angle
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Preterm Labor, Periodontal Disease
Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor
The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preterm labor.
- Trial name
- NCT03610841
- Testing
- preterm labor, healthy
- Where
- 6 sites in Turkey (Türkiye), United Kingdom
- Volunteers
- 100 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Labor Pain, Obstetric Pain
Color Doppler Ultrasound to Locate Needle in Labor Epidural
Color Flow Doppler (CFD) utilizes Doppler information obtained from signals sent to and received from a transducer. This information is color-encoded and then displayed as color on an overlay of the two-dimensional image.
- Trial name
- NCT03596333
- Testing
- Retrospective chart review
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Augusta University
Pelvic Floor Disorders, Ultrasound Therapy; Complications
Role of Rehabilitation for the Repair of Pelvic Floor Injuries Associated to Vaginal Delivery Identified by 3/4D Transperineal Ultrasound
SUMMARY: (Objective, design, scope of the study, subjects of study, instrumentation, results, conclusions) Objectives: To evaluate if the physiotherapy treatment in pelvic floor dysfunctions, identified by transperineal…
- Conditions
- Pelvic Floor Disorders, Ultrasound Therapy; Complications, Physical Disorder, Obstetric Labor Complications
- Trial name
- NCT03592160
- Testing
- Physiotherapy treatment
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital Universitario de Valme
Radiation, Obstetric Labor Complications
Performance Evaluation of System EOS Imaging in Pelvimetry Versus Pelvi-scanner
The purpose of this study and demonstrate the reliability of EOS imaging system in the measurement of internal diameters of obstetrical pelvis versus "Goldstandard current "that is the pelviscanner.
- Conditions
- Radiation, Obstetric Labor Complications, Pregnancy Complications
- Trial name
- PELVI-EOS (NCT02834897)
- Testing
- EOS and CT Exam
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pregnancy Complications, Obstetric Labor, Premature
Interest of Measuring Lung Elasticity ELASTOgraphy in the Fetus in the Case of PreMAture Childbirth Threat
The objective of the study was to evaluated the feasibility and reproducibility of the measurement of lung elasticity report / fetal liver according to gestational age in a group of patients with a normal course of pregnancy and…
- Trial name
- ELASTOMAP (NCT02870608)
- Testing
- lung and liver elastography measurement of fetus
- Where
- France
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Preterm Labor
Intramuscular Hydroxyprogesterone Caproate and Placenta Previa
Antepartum hemorrhage is defined as bleeding from or within the female genital tract, occurring from 24+0 weeks of pregnancy and till delivery of the fetus.
- Trial name
- NCT03130504
- Testing
- 17α hydroxy progesterone caproate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Preterm Labor
Ultrasonographic Evaluation of Fetal Adrenal Gland in Cases of Threatened Preterm Labor
Preterm birth continues to be a major public health problem with lasting family and societal repercussions. Despite tremendous research effort, prevention strategies have failed, and the prevalence of preterm birth in the United…
- Trial name
- NCT03251794
- Testing
- three dimensional ultrasound, color Doppler
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Preterm Labor
Oral Versus Parental Progesterone in the Management of Preterm Labor
Preterm birth, defined as delivery at less than 37 weeks gestation, complicates approximately 12% of pregnancies in the United States Preterm delivery has been, and remains, the most important challenge to modern obstetrics.
- Trial name
- NCT03343795
- Testing
- oral progesterone, intramuscular progesterone
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Preterm Labor
Different Types of Progesterone in the Prevention of Preterm Labor
Preterm birth is a common problem in obstetric care,with estimates ranging from 5% in several European countries to 18% in some African countries, Preterm labor defined as delivery before 37 completed weeks is the leading cause…
- Trial name
- NCT03537287
- Testing
- 17 alpha hydroxyprogestrone caproate, Vaginal progesterone, Oral dydrogesterone
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University