Clinical trials: Labor, Obstetric
Placenta Accreta
Placenta Accreta; Total Lower Uterine Segmentectomy With Cervico-corporeal Anastomosis
To study feasibility and safety of Total lower uterine segmentectomy with cervico-corporeal anastomosis in conservative management of placenta accreta
- Trial name
- NCT05419804
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Assiut University
Premature Birth
Interdisciplinary Hospital-home Intervention on Motor Development in Premature Children
Motor development of the premature infant often exhibits deviations that trigger functional limitations and disability. In Colombia, one out of every five births corresponds to premature babies.
- Trial name
- NCT04563364
- Testing
- Interdisciplinary hospital-home intervention, Convencional treatment
- Where
- Colombia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad de la Sabana
Premature Birth of Newborn
Supporting and Enhancing NICU Sensory Experiences (SENSE)
Seventy preterm infants born less than or equal to 32 weeks gestation were put into either the sensory-based intervention (experiment) group or traditional care (control) group. Consecutive admissions at St.
- Trial name
- SENSE (NCT03316547)
- Testing
- SENSE Program
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Preterm Birth
Physical Exam Indicated Cerclage in Singleton Gestation 24 Weeks to 25 Weeks and 6 Days Gestation
RCT assessing preterm delivery rate in singleton pregnancies having a physical-exam indicated cerclage placed between 24 weeks and 25 weeks and 6 days.
- Trial name
- NCT05501938
- Testing
- Physical Exam Indicated Cerclage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Placenta Previa Without Hemorrhage
Uterine Artery Ligation to Decrease Blood Loss With Central Placenta Previa
This trial will address the effect of uterine artery ligation during Cesarean section in cases with placenta previa to decrease blood loss.
- Trial name
- NCT02002026
- Testing
- Uterine artery ligation
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Minia Maternity University Hospital
Neonatal Respiratory Distress
Aerosolized Infasurf Treatment Protocol: Aerosolized Infasurf for Spontaneously Breathing Patients With Early RDS (AERO-03)
Surfactant replacement therapy can be life-saving for newborn infants born with symptomatic lung surfactant deficiency causing Respiratory Distress Syndrome (RDS).
- Trial name
- NCT03582930
- Testing
- Infasurf Aero
- Where
- 5 sites in United States
- Sponsor
- ONY
Placenta Accreta, Unspecified Trimester
Association of Ultrasonographic Parameters With FIGO Clinical Grading System for Placenta Accreta Spectrum
To evaluate the association of ultrasonographic parameters suggestive of placenta accreta with intraoperative clinical diagnosis of placenta accreta according to the the clinical grading system for placenta accreta spectrum (PAS)…
- Trial name
- NCT04801706
- Testing
- Ultrasound
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Assiut University
Neonatal Hypoglycemia, Neonatal Hyperglycaemia
Glucose Disturbances in Premature Infants and Quality of Life
The aim of this study is to investigate the correlation between preterm birth, glucose level in the first two hours of life and health related quality of life in the age of 8 months and 7 years
- Trial name
- NCT04770636
- Where
- Croatia
- Volunteers
- 150 people
- Sponsor
- Clinical Hospital Center Rijeka
Premature; Infant, Light-for-dates, Feeding Patterns
Comparison of Regional Splanchnic Tissue Oxygenation Measured by NIRS in Preterm Babies Fed Bolus Versus Continuous Feeding
Early initiation of enteral feeding, achievement of full enteral feeding and cessation of parenteral nutrition are extremely important in the very premature infant.
- Trial name
- NCT02072109
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Meir Medical Center
Preterm Infant
Executive Functions and Preterm Children in 3 to 4 Year Old
Preterm children have a high risk for neurodevelopmental impairments. The impact on motor functions and neurosensory functions is demonstrated but the incidenceof executive functions is not described for preterm infants.
- Trial name
- NCT03700463
- Testing
- BRIEF parental survey
- Where
- France
- Volunteers
- 356 people
- Sponsor
- Nantes University Hospital
Birth; Prolonged
Acceptability Assessment of an Optimized Birthing Position
This qualitative study evaluates the acceptability of positioning pregnant women in labour in an optimized position, which consists in the hyperflexion of the legs and the loss of the lumbar lordosis.
- Trial name
- NCT04056793
- Testing
- Optimized birthing position
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Preterm Birth, Cervical Incompetence
Preventing Preterm Birth With a Negative Pressure Cervical Cup: a Feasibility Study
The goal of this Phase I clinical trial is to generate proof-of-concept data to demonstrate that a cervical cup in combination with vacuum application will create negative pressure on uterine cervical tissue, thereby creating…
- Conditions
- Preterm Birth, Cervical Incompetence, Cervical Insufficiency, Short Cervix
- Trial name
- NCT05512052
- Testing
- Hannah Cervical Cup (2 mm Delta), Hannah Cervical Cup (4 mm Delta), Hannah Cervical Cup (6 mm Delta)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Galena Innovations, LLC
Prematurity, Nutrition
Nutritional Content of Breast Milk From Mothers of Premies
The purpose of this study is to determine the correlation, if any, between the nutritional content of breast milk pumped by the mothers of very low birth weight (VLBW) infants in the neonatal intensive care unit (NICU) and the…
- Trial name
- NCT01050192
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Health Problems in Pregnancy, Pregnancy Outcomes
Peking University Birth Cohort in Weifang (PKUBC-WF)
The PKUBC-WF is a prospective cohort study carried out in Weifang city of Shandong, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and…
- Conditions
- Health Problems in Pregnancy, Pregnancy Outcomes, Gestational Diabetes, Gestational Hypertension
- Trial name
- NCT06234332
- Testing
- No Interventions
- Where
- China
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Peking University
Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage
HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency
The objective of the Expanded Access Program is to provide HEMOLEVEN, a replacement coagulation factor XI, to patients with severe inherited factor XI deficiency where, in the opinion of the treating physician, the benefits of…
- Conditions
- Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage, Surgery
- Trial name
- EAP (NCT01701947)
- Testing
- Hemoleven
- Where
- United States
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Risk Factors
Risk Factors of Preterm Birth Born in Hospital：a Prospective Multicenter Case-control Study
The purpose of this study is to explore the perinatal risk factors of preterm birth in China.
- Trial name
- RFPTB (NCT03602625)
- Where
- 15 sites in China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Premature Birth, NEC
Prenatal Administration of Spermine Promotes Maturation of Premature Fetal Gut Epithelial Tight Junction: Experimental Study on Fetal Rabbit
Infections, particularly on the gastrointestinal tract, has been known to be one of the leading causes of death in preterm infants. This is due to the immaturity of the intestinal epithelial cells.
- Trial name
- NCT04004091
- Testing
- Spermine
- Where
- Indonesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- dr. Riana Pauline Tamba, SpB(K)BA
Weight, Birth, Premature Birth
Effects of Olfactory and Gustatory Stimulus on the Nutrition of Premature Babies
The objective of this clinical trial is to test the effects of olfactory and taste stimulation with milk or water in premature newborns with a gestational age between 28 and 32 weeks.
- Trial name
- NCT06305052
- Testing
- Milk, Water
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Prematurity
Impact of Different Electric Pumping Modalities on Milk Volume Production in Mothers of Preterm Infants
Initiating and sustaining breastfeeding are common challenges in neonatal units. It is known that hindmilk expressed at the end of the expression session has a higher fat content.
- Trial name
- NCT01802047
- Testing
- milk expression with electric pump
- Where
- Israel
- Sponsor
- Tel-Aviv Sourasky Medical Center
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