Clinical trials: Labor, Obstetric
School Readiness
Evaluation of Neurological Status and School Readiness in Preterm Preschoolers
Beginning school is an important milestone for children. Children's readiness for school involves cognitive, physical, and emotional development.
- Trial name
- NCT03081624
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Anti-Mullerian Hormone Deficiency, Post Partum Hemorrhage
Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)
Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. There are many studies about AMH changes in ovarian surgery, but little is known for other surgeries.
- Trial name
- NCT03907605
- Testing
- anti- mullerian hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Apnea
Prophylactic Versus Therapeutic Caffeine for Apnea of Prematurity
Investigators hypothesized that the timing of caffeine administration in either prophylaxis or treatment of apnea of prematurity will affect the apnea response to caffeine
- Trial name
- NCT02677584
- Testing
- Prophylactic caffeine citrate, Therapeutic caffeine citrate
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Mansoura University Children Hospital
Preterm Birth
Transvaginal Ultrasound: Preterm Birth Prevention in Appalachia
Preterm Birth is the number one cause of infant morbidity and mortality worldwide and represents an important health disparity in the United States, particularly across the state of Kentucky.
- Trial name
- NCT03833284
- Testing
- Participant Barriers to TVU Screening, Provider Barriers to TVU Screening
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Niraj Chavan
Pregnancy Related, Cervical Insufficiency
Cervical Stiffness Measurement in Cervical Insufficiency
The goal of this cross sectional study is to evaluate the differences in cervical stiffness between patients who present for cerclage placement versus normal pregnancies.
- Conditions
- Pregnancy Related, Cervical Insufficiency, Preterm Birth
- Trial name
- NCT04158401
- Testing
- Pregnolia
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Preterm Labor
Oral Progestogen Supplementation in the Prevention of Recurrent Uterine Contraction in Preterm Labor
The purpose of this study is to evaluate the effect of oral progesterone supplementation in preterm labor on the prevention of recurrent uterine contraction and prolonging pregnancy period, and its side effect.
- Trial name
- NCT02262481
- Testing
- dydrogesterone
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Face, Newborn
Fitting of Commonly Available Face Masks for Late Preterm and Term Infants
Around ten percent of newborn infants require positive pressure ventilation (PPV) in the delivery room. This is most commonly delivered using a round or anatomically shaped face mask attached to a T-piece device, self-inflating…
- Conditions
- Face, Newborn, Preterm Infant
- Trial name
- CAFF (NCT03369028)
- Testing
- 2D and 3D image of infants´ faces
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Respiratory Distress Syndrome, Newborn
Feasibility Study of Placement and Surfactant Administration Through a Preterm Size Laryngeal Mask Airway in Very Low Birth Weight Neonates With Respiratory Distress Syndrome
Surfactant administration via a supraglottic airway device or laryngeal mask airway (SALSA) is a minimally invasive method of instilling surfactant in the trachea during spontaneous breathing and after applying nasal continuous…
- Trial name
- NCT06606444
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways
- Where
- Vietnam
- Volunteers
- 45 people
- Sponsor
- Karolinska Institutet
Continuous Positive Airway Pressure
Effect of Continuous Positive Airway Pressure Delivered by Two Different Modalities on Breathing Pattern in Preterm Infants
In this study, the investigators want to observe how continuous positive airway pressure delivered by two different modalities affects breathing pattern in small preterm infants.
- Trial name
- NCT01326975
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Macrosomia, Induction of Labour
Induction of Labour for LGA fœtus in Women Without Insulin-treated Diabetes.
A french study published in 2015 (DAME) showed a decrease of shoulder dystocia and an increase of spontaneous vaginal delivery when the non insulin-treated diabetes patients with large-for-date fetus were induced.
- Conditions
- Macrosomia, Induction of Labour, Non-insulin-dependent Diabetes
- Trial name
- NCT03355040
- Testing
- induction of labour
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Preterm Birth
Adolescents Born Preterm; Nurtured Beginnings
This research study is a long-term follow-up to an earlier study of developmental care. For that study, high risk preterm newborns were randomly assigned to a standard care group, which received the standard care offered in the…
- Trial name
- NCT00310869
- Testing
- Individualized Developmental Care in the NICU
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Boston Children's Hospital
Premature, Placental Transfusion
Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications and Effect on Their Hematological Profile
The objective of this study is to evaluate the general course and prognosis associated with different methods of placental transfusion (Intact umbilical cord milking, cut- umbilical cord milking and delayed cord clamping) in…
- Trial name
- NCT06812507
- Testing
- intact umbilical milking, cut umbilical milking, Delayed cord clamping
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Preterm Birth, Premature Birth
Cervical Pessary Treatment for Prevention of s PTB in Twin Pregnancies on Children's Long-Term Outcome
Preterm birth (PTB) complicates 13% of all pregnancies worldwide and is the most important cause of neonatal morbidity and mortality. Women with a twin pregnancy are at increased risk of preterm delivery.
- Trial name
- Impetus (NCT03418311)
- Testing
- Cervical Pessary-Group
- Where
- 10 sites in Australia, Germany and 2 more
- Volunteers
- 672 people
- Sponsor
- Bürgerhospital Frankfurt
Preterm Delivery, Atopy
Impact of Fish Oil Supplementation in 3rd Trimester of Pregnancy on Maternal and Offspring Health
The aim of the trial is to investigate the effect of daily supplementation with 2.7 grams of long chain n-3 fatty acids during the third trimester of pregnancy.
- Conditions
- Preterm Delivery, Atopy, Metabolic Syndrome
- Trial name
- NCT01353807
- Testing
- Fish oil, Olive oil
- Where
- Denmark
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Centre for Fetal Programming, Denmark
Premature Infants
A Randomized Trial of Outpatient Oxygen Weaning Strategies in Premature Infants
The investigators hypothesize that Recorded Home Oximetry (RHO) utilization will not increase rates of respiratory-related re-hospitalizations and ED visits, and will not impair growth compared to standard oxygen management…
- Trial name
- NCT01994954
- Testing
- RHO
- Where
- 8 sites in United States
- Volunteers
- 196 people
- Sponsor
- University of Massachusetts, Worcester
Twin; Complicating Pregnancy, Postpartum Hemorrhage
Prophylactic Methylergonovine for Twin Cesarean
Obstetrical hemorrhage (excessive bleeding related to pregnancy) is a leading cause of maternal morbidity (disease or symptom of disease) and mortality (death) worldwide with a significantly higher frequency and severity…
- Trial name
- NCT05772156
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Columbia University
Premature Birth
Family Integrated Care in the NICU
In the highly technological environment of the modern neonatal intensive care unit (NICU), the infant is physically, psychologically and emotionally separated from its parents.
- Trial name
- FICare (NCT01852695)
- Testing
- Family Integrated Care
- Where
- 15 sites in Canada
- Volunteers
- 720 people
- Sponsor
- Mount Sinai Hospital, Canada
Intra-amniotic Infection
Non-invasive Test to Detect Intra-amniotic Infection in Women With Preterm Labor and Intact Amniotic Membranes
The purpose of this study is to collect clinical specimens and corresponding clinical data to develop a non-invasive test for detection of intra-amniotic infection and prediction of preterm birth in women and intact amniotic…
- Trial name
- IAI (NCT00700219)
- Where
- 21 sites in United States
- Volunteers
- 900 people
- Sponsor
- ProteoGenix, Inc.
Prematurity of Fetus
Pharmacokinetics of Oseltamivir in Newborns and Infants
Oseltamivir dosing in infants < 3 months of age is based on a single pharmacokinetic study in 20 infants from a single center. This dataset is limited by a lack of robustness, because only 1 sample was collected from each…
- Trial name
- NCT01388439
- Testing
- Oseltamivir
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- St. Louis Children's Hospital
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
Pilot Trial of Surfactant Booster Prophylaxis For Ventilated Preterm Neonates
A research study that will evaluate if giving surfactant medication to premature babies weighing < 1250 gm at birth during the second and third weeks of life will help their lungs.
- Trial name
- NCT00208039
- Testing
- Infasurf
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
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