Clinical trials: Labor, Obstetric
Placenta Accreta Spectrum, Placenta Previa
Hematological and Coagulation Markers in Predicting Placenta Accreta Spectrum in Placenta Previa
Placenta accreta spectrum (PAS) is a serious pregnancy complication where the placenta attaches too deeply into the wall of the uterus.
- Trial name
- NCT07826247
- Volunteers
- 130 people
- Sponsor
- Assiut University
Premature (Early) Ejaculation
On-demand Silodosin 4mg vs Dapoxetine 60mg in Treatment of Primary Premature Ejaculation
Both Silodosin 4 mg and Dapoxetine 60 mg significantly improved IELT and sexual function scores in primary PE patients. However, Silodosin exhibited a more favorable tolerability profile with fewer side effects, making it a…
- Trial name
- NCT07081659
- Testing
- sildosin 4mg, dapoxetine 60mg
- Where
- Egypt
- Volunteers
- 95 people
- Sponsor
- Benha University
Anemia of Prematurity
Effects of Transfusion Thresholds on Neurocognitive Outcome of Extremely Low Birth Weight Infants
To compare the effect of restrictive versus liberal red blood cell transfusion thresholds on long-term neurodevelopmental outcome in extremely low birth weight infants.
- Trial name
- ETTNO (NCT01393496)
- Testing
- red blood cell transfusion
- Where
- 32 sites in Denmark, Germany
- Volunteers
- 1,013 people
- Sponsor
- University Hospital Tuebingen
Preterm Birth, Preeclampsia
The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health
The 'Standard of Care Plus' ('PLUS') model in the ROOT Study consists of analyzing select micronutrient and gene variants of pregnant females to construct trimester-specific and personalized nutrition and lifestyle…
- Conditions
- Preterm Birth, Preeclampsia, Gestational Diabetes Mellitus (GDM), Small for Gestational Age (SGA)
- Trial name
- ROOT (NCT07559773)
- Testing
- 'Standard of Care PLUS'
- Volunteers
- 500 people
- Sponsor
- GrowBaby Life Project
Post-partum Hemorrhage, Blood Transfusion
Risk Factors, Management and Complications of Severe Post-partum Hemorrhage
The incidence of severe post-partum hemorrhage has been increasing in developed countries. The reason for this is at least partially unknown.
- Trial name
- PPH-REG (NCT02815605)
- Where
- Finland
- Volunteers
- 9,000 people
- Sponsor
- Tampere University Hospital
Prematurity, Necrotizing Enterocolitis
Collaborative Research Group for Necrotizing Enterocolitis
This proposal will test the hypothesis that synthesis and catabolism of epidermal growth factor (EGF), the genotype of the EGF gene, and the microbiome interact to influence EGF expression in infants at risk for necrotizing…
- Trial name
- NCT00828451
- Testing
- [5,5,5-2H3]leucine (stable isotope labeled leucine)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Washington University School of Medicine
Premature Birth of Newborn
The Adding Value of Parents to Nursing Care in the Control of FiO2
The purpose of this study is to determine whether saturation control by parents in children younger than 32 weeks or under 1500 g versus conventional care performed by nursing increases the time in which these patients remain at…
- Trial name
- NCT02306317
- Testing
- Standard procedure, Experimental procedure
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Carmen Rosa Pallas
Macrosomia, Induction of Labour
Induction of Labour for LGA fœtus in Women Without Insulin-treated Diabetes.
A french study published in 2015 (DAME) showed a decrease of shoulder dystocia and an increase of spontaneous vaginal delivery when the non insulin-treated diabetes patients with large-for-date fetus were induced.
- Conditions
- Macrosomia, Induction of Labour, Non-insulin-dependent Diabetes
- Trial name
- NCT03355040
- Testing
- induction of labour
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Montpellier
Premature Ventricular Complexes Multiple, Premature Ventricular Contraction
The Prognostic Significance of Premature Ventricular Complexes in Patients Without Structural Heart Disease
With this project the investigators aim to investigate whether premature ventricular complexes (PVC) have a prognostic significance in persons without structural heart disease.
- Trial name
- PULSE (NCT03370679)
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Danderyd Hospital
Preterm Labor
Uterocervical Angle and Preterm Labour
To determine whether a novel ultrasonographic marker, uterocervical angle, correlates with risk of spontaneous preterm birth
- Trial name
- NCT04532086
- Testing
- Uterocervical angle
- Volunteers
- 197 people
- Sponsor
- Ain Shams Maternity Hospital
Position Differences, Nutrition
Effect of Cradle Position During Orogastric Tube Feeding on Comfort, Physiological Parameters and Vomiting
The study was planned to determine the effect of the cradle position applied during orogastric tube feeding in premature newborns on comfort, physiological parameters and vomiting frequency.
- Conditions
- Position Differences, Nutrition, Nursing Care
- Trial name
- CRADLE (NCT06759285)
- Testing
- Experimental (cradle position)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Selcuk University
Premature Birth, Infant, Extremely Low Birth Weight
Additional Protein Fortification in Extremely Low Birth Weight Infants
Postnatal growth is a crucial in premature infants as it could be correlated with the long-term cognitive development. Optimal nutritional care is required to reduce the initial weight loss and further growth deficit.
- Conditions
- Premature Birth, Infant, Extremely Low Birth Weight, Growth Failure
- Trial name
- PROTSUP (NCT02515266)
- Testing
- nutrition: protein intake
- Volunteers
- 152 people
- Sponsor
- Hôpital de la Croix-Rousse
Chronic Lung Disease of Prematurity, Respiratory Distress Syndrome in Premature Infant
PAL to Improve Oral Feeding for Infants With Chronic Lung Disease
The purpose of this study is to investigate the effects of the Pacifier Activated Lullaby (PAL) intervention on the transition to oral feeding for preterm infants with chronic lung disease and respiratory distress syndrome that…
- Conditions
- Chronic Lung Disease of Prematurity, Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia, Preterm Birth
- Trial name
- NCT05446389
- Testing
- Pacifier Activated Lullaby ®
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Missouri-Columbia
Premature Birth
Total Parenteral Nutrition Associated Cholestasis (TPNAC) and Plasma Amino Acid Levels in Neonates
The purpose of this study is to analyze if the infants who received Primene solution, have lower serum levels of methionine and cysteine and higher serum levels of taurine, we also analyze if the infants who received Primene…
- Trial name
- TPNAC (NCT01062724)
- Testing
- Primene 10 % from Baxter
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Premature Birth
Age of Red Blood Cells in Premature Infants Study (ARIPI)
To determine if the age of blood transfused to new borns in the NICU setting has an impact on their outcome.
- Trial name
- NCT00326924
- Testing
- Transfusion
- Where
- Canada
- Volunteers
- 377 people
- Sponsor
- Ottawa Hospital Research Institute
Premature Infant
Cincinnati Infant Neurodevelopment Early Prediction Study (CINEPS)
The Early Prediction Study is a longitudinal population-based cohort study for very preterm infants ≤32 weeks gestational age. Preterm infants recruited from three greater Cincinnati and two Dayton area neonatal intensive care…
- Trial name
- NCT03345069
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Extreme Prematurity
Preterm Erythropoietin Neuroprotection Trial (PENUT Trial)
Recombinant human erythropoietin (Epo) is a promising novel neuroprotective agent. Epo decreases neuronal programmed cell death resulting from brain injury; it has anti-inflammatory effects, increases neurogenesis, and protects…
- Trial name
- PENUT (NCT01378273)
- Testing
- Epo, Control
- Where
- 19 sites in United States
- Volunteers
- 941 people
- Sponsor
- University of Washington
Bronchopulmonary Dysplasia (BPD), Respiratory Distress Syndrome
The Budesonide in Babies (BiB) Trial
This is a Phase 3, randomized, masked, active-controlled, multicenter trial designed to determine whether early intratracheal administration of a combination of budesonide with surfactant, as compared to surfactant alone, will…
- Conditions
- Bronchopulmonary Dysplasia (BPD), Respiratory Distress Syndrome, Prematurity; Extreme, Neonatal
- Trial name
- BiB (NCT04545866)
- Testing
- budesonide (Pulmicort nebulizing suspension)., surfactant (poractant alfa;Curosurf)
- Where
- 19 sites in United States
- Volunteers
- 642 people
- Sponsor
- NICHD Neonatal Research Network
Premature Birth
Development Training in Babies Born Preterm
The specific purpose of this study is to determine the effect of movement training on the onset of motor skills in babies born prematurely.
- Trial name
- NCT00268931
- Testing
- Movement Training, Social Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Christiana Care Health Services
Premature Birth
Neural Development and Its Influencing Factors in Premature Infants With Chronic Lung Disease
Current approaches to treatment of premature infants at risk for neurodevelopmental disabilities have emphasized early assessment and intervention within the first year of life to optimize their developmental outcome.
- Trial name
- NCT00155831
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
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