Clinical trials: Labor, Obstetric
Preeclampsia, Eclampsia
RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil
The perinatal morbidity and mortality rates for Brazil are five to ten-fold higher than those reported for upper income countries.
- Conditions
- Preeclampsia, Eclampsia, HELLP Syndrome, Pregnancy
- Trial name
- NCT00097110
- Testing
- Vitamin C and E
- Where
- Brazil
- Volunteers
- 734 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Morbidly Adherent Placenta
Role of Ultrasound in Diagnosis of Placenta Previa and MAP
Placenta accreta occurs when the placental implantation is abnormal. The marked rise in incidence has been assumed the increasing prevalence of cesarean delivery in recent years.
- Trial name
- NCT03416296
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Chorioamnionitis, Early Onset Neonatal Sepsis
Chorioamnionitis: Observation of at Risk Infants vs Standard Care
This study evaluates the non-inferiority of a protocol of limited evaluation (complete blood count, blood culture) and clinical observation by standardized physical examination versus the algorithm suggested in the CDC's 2010…
- Conditions
- Chorioamnionitis, Early Onset Neonatal Sepsis, Sepsis of the Newborn
- Trial name
- CHORIS-RCT (NCT02886910)
- Testing
- Clinical observation, Standard management
- Where
- Italy
- Sponsor
- IRCCS Burlo Garofolo
Prematurity, Respiratory Distress Neonatal
Effect of Automated Oxygen Control on Early-childhood Lung Mechanics
Preterm infants are at higher risk of long-term respiratory problems and abnormal lung function in childhood. Respiratory support including mechanical ventilation, that is the use of a machine to move air into and out of the…
- Conditions
- Prematurity, Respiratory Distress Neonatal, Oxygen Delivery
- Trial name
- NCT07866820
- Testing
- Forced oscillometry technique
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College Hospital NHS Trust
Newborn
Breastfeeding Rates at the Department of Neonatology of University Hospital Cologne
The objective of this study is to measure the breastfeeding success for all preterm and term newborns in our department of neonatology during the hospital stay and at the age of six months.
- Trial name
- BFRUHC (NCT02464579)
- Where
- Germany
- Volunteers
- 450 people
- Sponsor
- University Hospital of Cologne
Preterm Infant, Feeding Disorder Neonatal
Oropharyngeal Administration of Mother's Milk in Preterm Infants and Gastrointestinal Motility
Mother's milk does not come in contact with the oropharyngeal pouch of preterm infants during gavage feeding. We hypothesized that stimulation of the oropharyngeal pouch using small amount of the mother's milk 5 minutes before…
- Conditions
- Preterm Infant, Feeding Disorder Neonatal, Gastrointestinal Motility Disorder
- Trial name
- OPAMM (NCT03552510)
- Testing
- Oro-pharyngeal Administration of Mother's Milk
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University Children Hospital
Preterm, Apnea of Prematurity
Efficacy of PIMUN by Reducing Intermittent Hypoxia Events
The goal of this clinical trial is to learn if the use of PIMUN(medical device) works to reduce the intermittent hypoxemia of 24-34 weeks of birth gestational age babies. . It will also learn about the safety of the use of PIMUN.
- Conditions
- Preterm, Apnea of Prematurity, Hypoxemia
- Trial name
- NCT07396103
- Testing
- Brain NIRS, Polysomnogram, Reactive oxydative species
- Where
- 2 sites in Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Preeclampsia
Pravastatin for Prevention of Preeclampsia
The primary purpose of this pilot study is to determine the pharmacokinetic (PK) parameters and collect preliminary safety data for pravastatin when used as a prophylactic daily treatment in pregnant women at high risk of…
- Trial name
- Statin (NCT01717586)
- Testing
- Pravastatin
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Magnesium Deficiency, Preterm Birth
A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy
The investigators propose a preventive strategy that may reduce the risk of placental vascular disease and its negative consequences for both the fetus (e.g., poor fetal growth or stillbirth)and mother (e.g., the hypertensive…
- Conditions
- Magnesium Deficiency, Preterm Birth, Extreme Immaturity
- Trial name
- NCT02032186
- Testing
- Magnesium citrate
- Where
- Brazil
- Volunteers
- 3,000 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Delivery Problem, Labor Pain
Effect of Virtual Reality for Pain Management During Intracervical Balloon Placement for Artificial Childbirth Induction
The labor induction concerns 22% of births in France. In the event of labor induction, in almost two thirds of cases, a cervical ripening method is used and the use of mechanical methods is observed for 8% of cervical ripening.
- Trial name
- VIRTUALMAG (NCT05155826)
- Testing
- Virtual Reality Headset
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Postpartum Hemorrhage
The Foley's Catheter Balloon to the Bleeding From Placenta Previa
Post-partum haemorrhage due to placenta previa is usually from the placental bed at the lower uterine segment and it occurs after the placenta separation.
- Trial name
- NCT02640885
- Testing
- Foley's cather ballon
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Prematurity, Extreme Prematurity
Use Of Nfant(R) Technology Feeding System For Infants Less Than 30 Weeks GA
The purpose of the study is to utilize the objective data provided by the nfant® suite of products, along with current NICU visual assessment and cue-based feeding practices, in order to determine if feeding performance outcomes…
- Trial name
- NCT04256889
- Testing
- nfant(R) feeding system
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Woman's
Term and Preterm Neonates (24-41 Weeks Gestational Age), Hematopoietic Stem Cell Transplant Recipient Children
Ontogeny of MAIT Cells in Neonates and Hematopoietic Stem Cell Transplant Recipients
The objective of this study is 1/ to determine the rate and kinetics of MAIT cell expansion and maturation in neonates in relation with gestational age, and in HSCT recipient children in relation with the source of donor stem…
- Trial name
- NEOMAIT (NCT02403089)
- Testing
- Tubes fund recovery blood count, the rest of the blood test and stool sample
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Premature Infant, Mothers
Efficacy of Expressive Writing in Mothers of Preterm Infants
Premature birth can lead the mother to lose control of herself, and be a contributor to the psychological stress experienced due to the sudden breakdown of the interaction with her infant because of hospitalization in a neonatal…
- Trial name
- NCT03423914
- Testing
- Expressive writing, Only Writing
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Universidad Industrial de Santander
Placenta Accreta
Diagnosis and Outcomes of Placental Accretism
The goal of this observational study is to evaluate the diagnostic ability of the main criteria currently adopted for the diagnosis of placenta accreta and to define the maternal outcomes in terms of complications of the…
- Trial name
- NCT06833606
- Where
- 7 sites in Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Placenta Accreta / Percreta
Prediction of Placenta Accreta Outcome in Pregnant Woman With Placenta Previa Using (hcg_h ) as Abiomarkers
To check if maternal serum (hcg _h ) in second and third trimester in pregnant woman with placenta previa can predict placenta accreta at delivery or predict adverse maternal and neonatal outcome
- Trial name
- NCT06761885
- Volunteers
- 74 people
- Sponsor
- Assiut University
Milk Production
A Trial Comparing Two Breast Pumps in Mothers Expressing Milk for Their Preterm Infants
This is a randomised controlled trial investigating the performance of two, 'state of the art' electric breast pumps in mothers who have delivered preterm infants.
- Trial name
- NCT00887991
- Where
- United Kingdom
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Institute of Child Health
Uterine Atony, Uterine Tone Disorders
Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections
Insufficient uterine tone resulting in atony can potentiate hemorrhage and adverse outcomes for the parturient. Oxytocin is the first pharmacologic agent used, followed by methylergonovine, carboprost, and misoprostol.
- Conditions
- Uterine Atony, Uterine Tone Disorders, Postpartum Hemorrhage
- Trial name
- NCT03303235
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Postpartum Hemorrhage, Waterbirth
Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth
During a waterbirth, blood lost in the pool between the birth of the baby and the mother's exit from the water cannot be collected or measured.
- Trial name
- NCT07884890
- Testing
- Water immersion during labor and birth
- Where
- 2 sites in Italy
- Volunteers
- 600 people
- Sponsor
- University of Campania Luigi Vanvitelli
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