Clinical trials: Labor, Obstetric
Bronchopulmonary Disease
Preterm Lung Patient Registry
The goal of the Preterm Lung Patient Registry is to collect data on individuals with neonatal lung disease to better understand the illness and ultimately improve their care and survival.
- Trial name
- NCT00951366
- Testing
- Patient Registry
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Boston Children's Hospital
Pregnancy Related, Premature Birth
Mueller Polarimetric Colposcopy for High-performance Detection of Cervical Changes During Pregnancy
Mueller polarimetric colposcopy appears to be a powerful tool for evaluating cervical microstructure modification during pregnancy. Some polarimetric parameters of the uterine cervix can be correlated with the gestational age.
- Trial name
- COLPOTERME (NCT04661553)
- Testing
- Mueller's polarimetric colposcopy "Group 1", Mueller's polarimetric colposcopy "Group 2"
- Where
- France
- Volunteers
- 683 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth
What is the Impact of Early Life Exposures on the Cardiovascular System in Young Adulthood?
The purpose of this study is to investigate whether early life exposures such as premature birth or exposure to preeclampsia before you are born results in long-term alterations in the cardiovascular system that increase risk of…
- Trial name
- EVS (NCT01487824)
- Where
- United Kingdom
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Oxford
GERD, Apnea Neonatal
Effects of Vented Base Feeding Bottle in Preterm Infants With GERD Symptoms.
Aim of the study is to evaluate the effects of vented base bottles on respiration-swallow patterns and on gastroesophageal refluxes in preterm infants with clinical suspect of gastroesophageal reflux disease (GERD).
- Trial name
- FeedGERD (NCT03031288)
- Testing
- A, B
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Prematurity; Extreme
A Study of Factors Associated With Failure of the Golden Hour Protocol in the Initial Care of Extremely Preterm and Very Low Birth Weight Newborns
Preterm infants are a particularly vulnerable population, especially during the first hours of life as they adapt to life outside the womb.
- Trial name
- PREM-GH (NCT07829562)
- Testing
- Golden hour
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Neonatal Prematurity, Massage Therapy
Massage Therapy in Premature Neonates
The goal of this clinical trial is to learn about the effects of Neonatal Touch and Massage Therapy on premature babies. The main questions it aims to answer are: Do babies who receive Neonatal Touch and Massage Therapy get…
- Trial name
- NCT06163586
- Testing
- Neonatal Touch and Massage Therapy
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
ECC, LBW Children
Association Between Early Childhood Caries, Low Birth Weight and Nutritional Risk Factors: (Cohort Study)
The aim of this study is to assess the ECC experience in children aged from 12 to 36 month with low birth weight children in comparison to normal birth weight.
- Trial name
- NCT04344366
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pregnancy Complications
Validating a New Method to Assess Estimated Blood Loss in the Obstetric Population
Postpartum hemorrhage (PPH) is the leading cause of maternal mortality in low-income countries and the primary cause of nearly one quarter of all maternal deaths globally.
- Trial name
- NCT03404375
- Testing
- Gauss Triton system
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Decision Making, Shared, Pregnancy
Navigating the Grey Zone for Antenatal Corticosteroids
The purpose of this study is to find out if including a decision support tool in clinical practice guidelines will improve how doctors discuss the option of antenatal corticosteroid treatment with patients who might deliver at 34…
- Conditions
- Decision Making, Shared, Pregnancy, Preterm Birth
- Trial name
- NCT04792112
- Testing
- Decision support tool
- Where
- 2 sites in Canada
- Volunteers
- 460 people
- Sponsor
- University of British Columbia
Postpartum Hemorrhage
Uterine Tamponade for Treatment of Primary Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is responsible for around 25% of maternal mortality worldwide reaching as high as 60% in some countries.
- Trial name
- NCT02568657
- Testing
- Celox group, Bakri Balloon
- Volunteers
- 66 people
- Sponsor
- Assiut University
PROM (Pregnancy)
PROM by AmnioQuick Duo+ in Egyptian Women
Preterm premature rupture of the membranes (PPROM) is responsible for one-third of all preterm births. Optimum treatment relies on accurate diagnosis and gestational age.
- Trial name
- NCT03435965
- Testing
- AmnioQuickDuo+
- Where
- 2 sites in Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Post-partum Hemorrhage, Blood Transfusion
Risk Factors, Management and Complications of Severe Post-partum Hemorrhage
The incidence of severe post-partum hemorrhage has been increasing in developed countries. The reason for this is at least partially unknown.
- Trial name
- PPH-REG (NCT02815605)
- Where
- Finland
- Volunteers
- 9,000 people
- Sponsor
- Tampere University Hospital
Extreme Prematurity, Enteral Nutrition
High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants
This Phase II, parallel-group, masked, randomized clinical trial aims to evaluate whether a DHA/ARA-enriched, fortified human milk diet administered during the first 14 days of life reduces respiratory morbidity and improves lung…
- Conditions
- Extreme Prematurity, Enteral Nutrition, Bronchopulmonary Dysplasia
- Trial name
- MEND-BPD (NCT07307612)
- Testing
- High-energy group, Standard-energy group
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Alabama at Birmingham
Massage, Premature Infant
Efficacy of Massage Applied by the Parents in Hospitalized Premature Birth (PreMas)
The purpose of this study was to analyze the efficacy of massage therapy and kinesiotherapy, applied by the parents of hospitalized preterm infants, in the improvement of the biological state, neuromotor activity and other…
- Conditions
- Massage, Premature Infant, Premature Birth, Preterm Infant
- Trial name
- PreMas (NCT03704012)
- Testing
- Protocol of massage therapy and kinesiotherapy
- Volunteers
- 143 people
- Sponsor
- Universidad de León
Bronchopulmonary Dysplasia
A Clinical Safety Study of AT-100 (rhSP-D) in Preterm Neonates at High Risk for Bronchopulmonary Dysplasia (BPD)
The purpose of this study is to determine if an investigational drug, AT-100, can reduce the occurrence of Bronchopulmonary Dysplasia (BPD) in babies born premature, as compared to babies born premature who receive an air-sham…
- Trial name
- NCT04662151
- Testing
- AT-100
- Where
- 19 sites in United States, Spain
- Volunteers
- 37 people
- Sponsor
- Airway Therapeutics, Inc.
Intestinal Perforation, Necrotizing Enterocolitis
IRT in Infants With Intestinal Perforation
This study is designed to evaluate a novel tool to aid in the diagnosis of intestinal perforation in infants who are at high risk.
- Trial name
- NCT01530828
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Preterm Birth Complication, Neonatal Morbidity and Mortality
Delayed Versus Immediate Cord Clamping in Preterm Birth
The goal of this study is to evaluate whether delayed cord clamping improves early neonatal outcomes compared with immediate clamping in preterm birth.
- Conditions
- Preterm Birth Complication, Neonatal Morbidity and Mortality, Cord Clamping, Delayed Cord Clamping
- Trial name
- PREM-CORD (NCT07699666)
- Testing
- Delayed Umbilical Cord Clamping, Immediate Umbilical Cord Clamping
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- Faculty of Medicine of Tunis
Pregnancy Related, Periodontitis
MOTOR: Maternal Oral Therapy to Reduce Obstetric Risk
The purpose of this study is to determine whether maternal periodontal therapy (tooth cleaning) decreases the rate of preterm deliveries at <37 weeks gestation and to determine the effects of maternal periodontal therapy on the…
- Conditions
- Pregnancy Related, Periodontitis, Premature Birth
- Trial name
- NCT00097656
- Testing
- multi-center, randomized, controled periodontal therapy
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infant, Premature, Diseases, Respiratory Tract Diseases
Effect of Volume Guarantee-High Frequency Oscillatory Ventilation on Cerebral Blood Flow in Neonates
A randomized controlled clinical trial evaluates cerebral blood flow changes associated with HFOV-VG in comparison to HFOV alone in preterm neonates with respiratory insufficiency during the period of invasive respiratory support
- Conditions
- Infant, Premature, Diseases, Respiratory Tract Diseases, Cerebral Blood Flow
- Trial name
- NCT05592431
- Testing
- High Frequency Oscillatory Ventilation with Volume Guarantee (SLE6000;SLE), High Frequency Oscillatory Ventilation (SLE6000;SLE)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
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