Clinical trials: Labor
Preterm Labor
Use of Pessary in Case of Cervical Insufficiency and Short Cervix
Prematurity is the most important cause of obstetric morbidity and mortality. Health centers and obstetricians are trying to reduce the preterm birth rate by taking into account the permanent effects of premature birth on human…
- Trial name
- NCT03096691
- Testing
- cervical pessary
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Preterm Labor, Preterm Contractions
Screening To Obviate Preterm Birth
Our objective is to investigate the predictive value of a panel of biomarkers associated with two biologically plausible pathways of preterm birth: membrane breakdown and cervical remodeling.
- Conditions
- Preterm Labor, Preterm Contractions, Abdominal Cramping, Back Pain
- Trial name
- STOP (NCT01868308)
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- University of Pennsylvania
Women Admitted to Labor and Delivery for the Management of Preterm Labor and/or Preterm Premature Rupture of Membranes (PPROM)
Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes
The thymus gland is a specialized organ in the chest that plays a central role in the adaptive immune system throughout development until puberty. In response to stress, the fetal thymus gland may shrink, or involute.
- Trial name
- TIPS (NCT01975792)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Labor Pain, Breathing Exercise
BREATHING EXERCISES FOR LABOR PAIN AND DURATION
This study aimed to assess the efficacy of breathing exercises (BE) during the second stage of labor for maternal pain, duration of labor and first-minute APGAR score.
- Trial name
- NCT03066973
- Testing
- BREATHING EXERCISE
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Prolonged Labor
Hyoscine Butyl Bromide for Management of Prolonged Labor
To determine the value of using Hyoscine as an antispasmodic drug for the management of prolonged labor in nulliparous women at term.
- Trial name
- NCT01854073
- Testing
- Hyoscine butyl bromide, Normal saline
- Where
- Saudi Arabia
- Volunteers
- 500 people
- Sponsor
- Ain Shams University
Prolonged First Stage of Labor
Use of an Antiemetic to Shorten the Length of Labor in Nulliparous Women
Reducing the length of labor is a highly desirable goal of intrapartum care, both from a perspective of maternal and fetal well-being , and for the providers of the birth services.
- Trial name
- NCT01937234
- Testing
- Metoclopramide
- Where
- Saudi Arabia
- Volunteers
- 250 people
- Sponsor
- Ain Shams University
Presentation; Breech, With External Version Before Labor
Moxibustion in a Randomized Trial for Version of Breech Position From Week 32
Moxibustion was tested for version of a breech position in singleton pregnancies. The women were randomized in week 32 to either moxibustion on acupuncture point Bl 67 daily in 15-20 minutes or no moxibustion.
- Trial name
- NCT02251886
- Testing
- Moxibustion in primiparae, Moxibustion in multiparae
- Volunteers
- 200 people
- Sponsor
- Herning Hospital
Preterm Labor
Magnesium Effect on Embryonal PR Interval
Magnesium is a known treatment for neuroprotection in preterm labor before 32 week of gestation. High concentration of Magnesium in the blood stream known as cause of conduction abnormalities and ECG changes such us prolonged QT…
- Trial name
- NCT03047304
- Testing
- Trans abdominal sonography
- Volunteers
- 25 people
- Sponsor
- Rambam Health Care Campus
Labor Pain
A Case Series of VPIA Using Remifentanil for Labour and Delivery
This study is a prospective case series aiming to evaluate a new VPIA remifentanil algorithm which would benefit labouring mothers who are unable or unwilling to receive epidural analgesia.
- Trial name
- VPIA (NCT02122705)
- Testing
- VPIA remifentanil
- Where
- Singapore
- Volunteers
- 29 people
- Sponsor
- KK Women's and Children's Hospital
Labor Pain
VPIA Remifentanil for Labour Pain to Reduce Maternal Desaturation and Improve Analgesic Titration
This study is a prospective cohort study aiming to evaluate an improved VPIA remifentanil algorithm which would benefit labouring mothers who are unable or unwilling to receive epidural analgesia
- Trial name
- NCT02733835
- Testing
- Remifentanil
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- KK Women's and Children's Hospital
Cesarean Section During Labor
Minimum Oxytocin Dose for Cesarean During Labor: Adaptative Clinical Trial
Introduction: postpartum hemorrage is a leading cause of death after cesarean sections in Brazil. Oxytocin is the main drug for both prophylaxis and threatment of postpartum hemorrage because uterine atony is the most prevalent…
- Trial name
- MODCL (NCT02794779)
- Testing
- Oxytocin
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Brasilia University Hospital
Laboring Women Requesting Neuraxial Labor Analgesia
Comparison of Epidural Labor Pain Relief Techniques on Maternal and Fetal Outcomes
The primary objective of this study is to compare the onset and duration of the initial dose of medications given through three different epidural (conventional epidural, combined spinal epidural and dural puncture epidural)…
- Trial name
- NCT02008591
- Testing
- Epidural Technique versus Dural Puncture Epidural Technique versus Combined Spinal Epidural Technique
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brigham and Women's Hospital
Preterm Labour
Comparison Between Amniotic Fluid Lamellar Body Count and Fetal Pulmonary Artery Doppler Indices in Predicting Fetal Lung Maturity
The investigators will study 200 women with singleton pregnancies presented with prelabor preterm rupture of membranes or undergoing cesarean section (CS).
- Trial name
- NCT02331199
- Testing
- Amniotic fluid lamellar body count, Fetal pulmonary artery Doppler
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Labor Induction
Dinoprostone Vaginal Insert Versus Double Balloon Catheter for Preinduction Cervical Ripening
Effıcacy of dinoprostone vaginal insert versus double- balloon catheter among women in the induction of labor
- Trial name
- NCT03016442
- Testing
- Cook Double Balloon Catheter, Dinoprostone
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Effects of; Anesthesia, in Labor and Delivery
Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
The purpose of the study is to determine if a medication called phenylephrine, which helps to control blood pressure, is more effective as a continuous intravenous (IV) infusion compared to continuous IV norepinephrine in…
- Trial name
- NCT02354833
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Labor Analgesia
Comparison of Programmed Intermittent Epidural Bolus With Continuous Epidural Infusion for Labor Epidural Analgesia
Sixteen million babies were born in 2010, approximately half were by cesarean. Labor analgesia should be the first choice for these parturients based on the consideration of security and humanization.
- Trial name
- NCT02873091
- Testing
- Epidural analgesia, Continuous epidural infusion, Intermittent epidural bolus
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Nanjing Maternity and Child Health Care Hospital
Tramadol for Labor Analgesia
Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial
Tramadol for labor analgesia: a low risk placebo controlled randomised control trial
- Trial name
- NCT02999594
- Testing
- Tramadol Hydrochloride, Distilled Water
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Maulana Azad Medical College
Labor Pain
Failure of Vaginal Delivery After Induction
The study will compare the number of women who deliver vaginally after artificial initiation of labor pains(i.e. induction of labor) by two methods.
- Trial name
- NCT02758340
- Testing
- Misoprostol, foley's balloon catheter
- Where
- Pakistan
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Karachi Medical and Dental College
Labor Pain
Effect of Epidural Analgesia on the Parameter ANI During Childbirth
There are many methods used for the assessment of pain in the area of anesthesia including heart rate variability which reflects the influence of the autonomic nervous system on the heart.
- Trial name
- APD-ANI (NCT01505283)
- Testing
- NaCl 0.9%, Sufentanil, lidocaine
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hopital Foch
Labor Pain
Comparison of Ultrasound Guided Low Epidural Catheter Placement With Standard Epidural Catheter Placement
1. labor epidural quite often require bolus supplementation for better pain control control. Quite often this is due to sparing of sacral nerves. 2.
- Trial name
- NCT01182220
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Chicago