Clinical trials: Labor Complication
Hemorrhage, Premature Infants
NIRS Monitoring in Premature Infants
This study uses frequency domain near-infrared spectroscopy coupled with diffuse correlation spectroscopy (FDNIRS-DCS) technology for monitoring cerebral blood flow (CBF) and cerebral oxygen metabolism (CMRO2) at the bedside for…
- Conditions
- Hemorrhage, Premature Infants, Newborn, Hydrocephalus
- Trial name
- NCT02601339
- Testing
- ETV/CPC
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Infant, Newborn, Diseases
Electrogastrography (EGC) in Premature Infants With Feeding Intolerance
Serial EGC measurements in premature infants attempting to correlate EGC measurements with signs of feeding intolerance and response to metoclopramide therapy.
- Trial name
- NCT00008736
- Testing
- metoclopramide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Preterm Labor
Uterocervical Angle in Idiopathic Polyhydramnios
To evaluate the performance of uterocervical angle (UCA) in the prediction of preterm labor in isolated polyhydramnios
- Trial name
- NCT03828695
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Prematurity
Umbilical Cord Milking on the Reduction of Red Blood Cell Transfusion Rates in Infants
Delayed cord clamp of at least 30 seconds in neonates under 37 weeks has shown that these infants have higher circulating blood volume in the first 24 hours, less need for blood transfusions, and less incidence of…
- Trial name
- NCT01523769
- Testing
- Umbilical Cord Milking
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Preterm Birth
Trial of the Use of Antenatal Corticosteroids in Developing Countries
Multi-country two-arm, parallel cluster randomized controlled trial to reduce neonatal mortality through increasing the rate of antenatal corticosteroid administration to eligible women.
- Trial name
- ACT (NCT01084096)
- Testing
- Increasing use of Antenatal Corticosteroids (ACS)
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 103,117 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Previous; Cesarean Section, Cicatricial, Complicating Pregnancy or Childbirth, Affecting Fetus or Newborn, Prelabor Rupture of Membranes
Balloon Induction of Labor in PROM for TOLAC
A prospective randomized controlled trial to evaluate the safety and efficacy of labor induction with a double balloon catheter (Atad Ripener Device) in women desiring TOLAC (trial of labor after cesarean) with PROM (pre labor…
- Trial name
- BILROM-TOLAC (NCT03399266)
- Testing
- Double Balloon catheter for induction of labor
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
To Compare Efficacy Intrauterine vs Sublingual MISOPROSTOL in Addition to Oxytocin in Reducing Blood Loss of Post-cesarean Section in High Risk Women
Sublingual vs Intrauterine MISOPROSTOL Plus Oxytocin Infusion for Prevention of Post-cesarean Hemorrhage in High Risk Pregnant Women: A Double-blind Placebo RCT
Research Objective: Primary outcome -To compare efficacy Intrauterine vs Sublingual MISOPROSTOL in addition to Oxytocin in reducing blood loss of post-cesarean section in high risk women Secondary outcome -To study…
- Trial name
- NCT04560218
- Testing
- sublingual Misoprostol, Intrauterine Misoprostol
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Postpartum Hemorrhage
Comparing Misoprostol and Oxytocin in UnijectTM for Postpartum Hemorrhage (PPH) Prevention in Mali
This is a large, community-based, cluster-randomized trial to compare routine prophylactic use of 600 mcg oral misoprostol and 10 IU oxytocin delivered by UnijectTM intramuscularly during the third stage of labor.
- Trial name
- NCT01487278
- Testing
- misprostol, UnijectTM
- Where
- Mali
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Postpartum Hemorrhage, Postpartum Preeclampsia
Postpartum Video Education
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression
- Trial name
- NCT05159726
- Testing
- Video Education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Preterm, Feeding, Bottle
Comparison of Bottle and Cup Feeding on Transition to Full Breastfeeding and Discharge Time
Breastfeeding is the ideal feeding method and that in the absence of breastfeeding the bottle and cup feeding are common alternatives. There is a lack of evidence regarding superiority of either of these methods.
- Conditions
- Preterm, Feeding, Bottle, Feeding Behavior, Feeding, Breast
- Trial name
- NCT04975282
- Testing
- Bottle feeding, Cup feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Premature Birth of Newborn, Enterocolitis, Necrotizing
A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome
The purpose of this study is to determine whether antibiotics given immediately after birth alter the development of the developing preterm infant's microbiome, which may further alter overall clinical outcomes.
- Trial name
- NCT02477423
- Testing
- Ampicillin, Gentamicins
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Preterm, Breastfeeding
The Effect of Breastfeeding Support System
This study aimed to examine the impact of a breastfeeding support system on breast milk production and mother-infant bonding in preterm infants.
- Conditions
- Preterm, Breastfeeding, Breast Milk, Breastfeeding Support System
- Trial name
- NCT06003959
- Testing
- Routine nursing care, breastfeeding support system
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Diabetes, Gestational
Outpatient Cervical Ripening With Orally Administered Misoprostol in Diabetics
A. Null Hypothesis: In term pregnancies complicated by diabetes, there is no difference in the time interval from start of induction to delivery when outpatient cervical ripening and labor induction is initiated with orally…
- Trial name
- NCT00514618
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Bacteremia, Infant, Very Low Birth Weight
Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants.
This study evaluates the potential interest of a new multi-lumen infusion access device (Edelvaiss® Multiline NEO) in the prevention of catheter-related bacteremia when administering injectable drugs in premature infants.
- Trial name
- MultilineNEO (NCT02633124)
- Testing
- Edelvaiss Multiline NEO, Standard Infusion Set
- Where
- 4 sites in France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Preterm Birth
What is the Impact of Early Life Exposures on the Cardiovascular System in Young Adulthood?
The purpose of this study is to investigate whether early life exposures such as premature birth or exposure to preeclampsia before you are born results in long-term alterations in the cardiovascular system that increase risk of…
- Trial name
- EVS (NCT01487824)
- Where
- United Kingdom
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Preterm Labor
Transabdominal Cervical Length Predict Preterm Labor During Routine Antenatal Screening
Sonographically, cervical length measurement is widely used in obstetrics. Studies have revealed that early detection of short cervix can be a predictor of predicting preterm labor.
- Trial name
- NCT04313673
- Testing
- second trimester ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Antenatal Care, Maternal Health
AI Blind-Sweep Ultrasound for Antenatal Screening by Non-Specialist Health Workers in Rural DR Congo
FS2 evaluates the diagnostic accuracy and implementation feasibility of an AI-assisted blind-sweep obstetric ultrasound (SPAQ E-con AI), operated by trained non-specialist health workers, for antenatal screening in rural…
- Conditions
- Antenatal Care, Maternal Health, Gestational Age, Placenta Praevia
- Trial name
- FS2 (NCT07677670)
- Testing
- SPAQ E-con AI blind-sweep ultrasound
- Where
- Democratic Republic of the Congo
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- SOIK Corporation Sarl
Early Labor
Membrane Sweeping in Early Labor and Delivery Outcomes
Membrane sweeping is a routine procedure in obstetrics in term patients. It has been shown to be effective in decreasing post term gestation and in increasing rate of spontaneous vaginal delivery when used in setting of induction…
- Trial name
- NCT03517696
- Testing
- Membrane sweeping
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
ECC, LBW Children
Association Between Early Childhood Caries, Low Birth Weight and Nutritional Risk Factors: (Cohort Study)
The aim of this study is to assess the ECC experience in children aged from 12 to 36 month with low birth weight children in comparison to normal birth weight.
- Trial name
- NCT04344366
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy Related, Periodontitis
MOTOR: Maternal Oral Therapy to Reduce Obstetric Risk
The purpose of this study is to determine whether maternal periodontal therapy (tooth cleaning) decreases the rate of preterm deliveries at <37 weeks gestation and to determine the effects of maternal periodontal therapy on the…
- Conditions
- Pregnancy Related, Periodontitis, Premature Birth
- Trial name
- NCT00097656
- Testing
- multi-center, randomized, controled periodontal therapy
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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