Clinical trials: Labor Delivery
Labor and Delivery
Does Oral Intake During Labor and Delivery Have an Effect on Complications and Outcome
The recommendations regarding eating and drinking during the labor and delivery process are not clear. The objective of this study is to assess whether eating and drinking during the labor process improves obstetric outcomes and…
- Trial name
- NCT03949166
- Testing
- food during labor and delivery
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Indications for Care in Pregnancy; Labor; and Delivery
Colostral Milk and Blood IL-6 Levels in Types of Labour
The comparison of serum and colostral melatonin, and IL-6 levels between women with vaginal delivery, emergency cesarean section and elective cesarean section
- Trial name
- NCT03953066
- Testing
- The calculation of blood IL-6 and coloctral milk melatonin
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Samsun Education and Research Hospital
Obesity, Labor Induction
Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obese pregnant women (BMI ≥ 30 kg/m2) are more likely than their normal-weight counterparts to require induction of labor because of increased rates of obstetric complications including pregnancy related hypertensive disorders…
- Conditions
- Obesity, Labor Induction, Cesarean Delivery
- Trial name
- CROWN (NCT02639429)
- Testing
- Vaginal Misoprostol, Foley Balloon + Vaginal Misoprostol
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Persistent Occipital Posterior Presentation During Labor Delivery
Trial of Prophylactic Manual Rotation of Persistent Occiput Posterior Presentation During the Early Second Stage of Labor to Reduce Operative Delivery: a Prospective Multicenter Randomized Control Trial
Superiority multicenter prospective randomized study on operative delivery (instrumental delivery or caesarean section) of prophylactic manual rotation in case of persistent occipital posterior presentation during the second…
- Trial name
- PROPOP (NCT02695238)
- Testing
- Prophylactic Manual Rotation of persistent occipital posterior presentation
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Labor Induction, Cesarean Delivery
Induction of Labor With Oxytocin: When Should Oxytocin be Held?
The investigators propose to perform a prospective randomized control trial to compare the rate of cesarean delivery in women where Oxytocin (OT) is discontinued once active labor begins (5 cm dilation) when compared with women…
- Trial name
- NCT00957593
- Testing
- Oxytocin, Oxytocin discontinuation
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Lehigh Valley Hospital
Other Specified Complications of Labor and Delivery
Vaginal Delivery Debrief Checklist to Improve Team Communication
This study is to determine if using a standardized debrief checklist after vaginal delivery improves communication between the vaginal delivery health care team members and if using the checklist increases a sense of enhanced…
- Trial name
- VDD (NCT01822158)
- Testing
- Vaginal Delivery Debrief Checklist
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Induced; Birth, Delivery Complication
The Norwegian Induction Project: a Pilot for a Prospective National Audit
The worldwide rate of induction of labour has been steadily increasing over the last 15 years, a trend that is reflected in Norway.
- Conditions
- Induced; Birth, Delivery Complication, Indications for Care in Pregnancy; Labor; and Delivery
- Trial name
- NCT03730220
- Where
- Norway
- Volunteers
- 1,846 people
- Sponsor
- Oslo University Hospital
Labor and Delivery
A Randomized Trial of Induction Versus Expectant Management
A randomized clinical trial to assess whether elective induction of labor at 39 weeks of gestation compared with expectant management will improve outcomes.
- Trial name
- ARRIVE (NCT01990612)
- Testing
- Elective Induction of Labor
- Where
- 16 sites in United States
- Volunteers
- 6,106 people
- Sponsor
- The George Washington University Biostatistics Center
Anesthesia; Adverse Effect, in Labor and Delivery
Incidence of Anesthesia-related Adverse Events and Obstetric Complications After Cesarean Delivery
Recruit the parturients who underwent cesarean delivery at Far Eastern MemorialHospital during 2012-2016. After reviewing medical record related to the pregnancy, demographic data, prenatal exam, laboratory data, indication for…
- Trial name
- NCT03391648
- Testing
- Observation
- Where
- Taiwan
- Volunteers
- 505 people
- Sponsor
- Far Eastern Memorial Hospital
Fetal Intrauterine Distress First Noted During Labor and or Delivery in Liveborn Infant, Team Based on Their Existing Guidelines and the Woman Consents to Have EFM and EFM is
Use of Decision Support in the Management of Labour
In women judged to require continuous electronic fetal heart rate monitoring (EFM) during their labour, does the addition of decision support software to aid the interpretation of the intrapartum cardiotocogram (CTG) reduce the…
- Conditions
- Fetal Intrauterine Distress First Noted During Labor and or Delivery in Liveborn Infant, Team Based on Their Existing Guidelines and the Woman Consents to Have EFM and EFM is, Possible
- Trial name
- INFANT (NCT02010710)
- Testing
- INFANT software
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 47,062 people
- Sponsor
- University College, London
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Pulse Pressure and Post-epidural Fetal Heart Rate Changes
Epidural anesthesia, the most common method of pain control in labor, can contribute to alterations in maternal blood pressure and/or fetal heart rate changes.
- Trial name
- NCT02565485
- Testing
- Lactated Ringer's
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- MetroHealth Medical Center
Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2
Cerclage for Twins With Short Cervix
A prospective randomized control trial that will compare cervical cerclage plus vaginal progesterone to vaginal progesterone along in twin pregnancies complicate by a short cervix (</= 15.0mm) between 16w0d to 25w6d.
- Conditions
- Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2, Cervical Incompetence, Cervical Shortening
- Trial name
- NCT03077633
- Testing
- Cervical Cerclage placement, Vaginal Progesterone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Preterm Delivery
Efficacy of Oral Progesterone and Vaginal Progesterone After Tocolytic Therapy in Threatened Preterm Labor
The purpose of this study is to determine efficacy of vaginal and oral progesterone after tocolytic therapy in threatened preterm labor
- Trial name
- NCT02989519
- Testing
- dydrogesterone, Micronized progesterone
- Where
- Thailand
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Sanpasitthiprasong Hospital
Preterm Labor Without Delivery
Tocolysis in Prevention of Preterm Labor
Preterm birth is defined as birth before 37 completed weeks of gestation .it occurs in 11.1%of birth globally affecting an estimated 14.9 million babies every year .
- Trial name
- NCT03298191
- Testing
- Magnesium Sulfate, Ritodrine, Calcium Channel Blockers
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Vacuum Extraction; Failure, Affecting Fetus or Newborn, Persistent Occiput Posterior Position During Labor
R. I. S. POS. T. A
A failed operative vaginal delivery is associated with increased risk of maternal and perinatal complications. It is very important the determination of the fetal head position prior to instrumental delivery.
- Conditions
- Vacuum Extraction; Failure, Affecting Fetus or Newborn, Persistent Occiput Posterior Position During Labor, Complication of Delivery
- Trial name
- RISPOSTA (NCT01991665)
- Testing
- Digital examination, Sonography evaluation
- Where
- Italy
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Women Admitted to Labor and Delivery for the Management of Preterm Labor and/or Preterm Premature Rupture of Membranes (PPROM)
Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes
The thymus gland is a specialized organ in the chest that plays a central role in the adaptive immune system throughout development until puberty. In response to stress, the fetal thymus gland may shrink, or involute.
- Trial name
- TIPS (NCT01975792)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Effects of; Anesthesia, in Labor and Delivery
Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
The purpose of the study is to determine if a medication called phenylephrine, which helps to control blood pressure, is more effective as a continuous intravenous (IV) infusion compared to continuous IV norepinephrine in…
- Trial name
- NCT02354833
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Complication of Labor and/or Delivery
Efficacy and Satisfaction With Remifentanil Analgesia in Parturients During the Childbirth
Retrospective observational study to determine the efficacy of remifentanil during the delivery. Authors will search the data in period between 2010 and 2014 in cohort of 100 parturients and obtain data of analgesic efficacy (VAS…
- Trial name
- NCT02447757
- Testing
- remifentanil
- Where
- 2 sites in Czechia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Anesthetic, Sedative or Analgesic Complications in Labor or Delivery
Trial of Onset of Epidural Pain Relief With Low Dose Bupivacaine and Different Doses of Fentanyl in Laboring Women
Epidural analgesia is the most effective form of labor pain relief. Low doses of local anesthetic (freezing solutions) in combination with opioids (narcotics) are commonly used as epidural solutions to provide pain relief.
- Trial name
- NCT02004899
- Testing
- Fentanyl
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's