Clinical trials: Labor Delivery
Preterm Delivery
Preterm Delivery Risk Prediction by Measurement of Prenatal Serum Screening Markers
This protocol seeks to longitudinally collect blood samples from a cohort of pregnant women. The biological specimens will be used to determine the predictive power of biochemical markers routinely used in Down syndrome screening…
- Trial name
- NCT01009723
- Where
- 2 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Esoterix Genetic Laboratories, LLC
Pre-Term, Respiratory Distress Syndrome, Newborn
NeO2Matic-Pilot Trial
The main goal of this trial is to test if: automated adjustment of supplemental oxygen to preterm infants in noninvasive respiratory support based on feedback from a measurement of blood-oxygen saturation results in more stable…
- Conditions
- Pre-Term, Respiratory Distress Syndrome, Newborn, Retinopathy of Prematurity, Bronchopulmonary Dysplasia
- Trial name
- NEO2MATIC (NCT05629910)
- Testing
- O2Matic
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anxiety
An Informative Video About Perineal Tears During Labor for Anxiety Reduction: A Randomized Controlled Trial
This study evaluates the impact of an informative video about perineal tears on maternal anxiety during labor. Perineal trauma during childbirth, especially severe tears such as obstetric anal sphincter injuries (OASIS), is…
- Trial name
- VITAL (NCT07064213)
- Testing
- Behavioral: Educational Video
- Where
- Israel
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Pregnancy
Routine Iron Prophylaxis During Pregnancy
Comparison of two policies of iron administration during pregnancy in regard to health and program feasibility in an area with endemic malaria and high prevalence of HIV infection.
- Trial name
- PROFEG (NCT00488579)
- Testing
- Two policies of iron prophylaxis
- Where
- Mozambique
- Volunteers
- 4,326 people, healthy volunteers welcome
- Sponsor
- National Istitute For Health and Welfare, Finland
Indication for Care or Intervention Related to Labor or Delivery With Baby Delivered
Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients
Anesthesiologists commonly administer pain relief during labor or providing anesthesia for cesarean delivery. Two main methods are used to achieve these goal: "Regional anesthesia" where the mother is given medication through a…
- Trial name
- DADB (NCT02193542)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Venipuncture, Pain
The Effect of Mother's Gentle Human Touch Method on Preterm Pain and Mother's Anxiety Level During Venipuncture
Newborns are frequently exposed to acute or chronic pain experience due to different invasive interventions. The American Academy of Pediatrics (AAP) recommends minimizing the pain associated with invasive procedures.
- Trial name
- NCT05727631
- Testing
- gentle human touch
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Stress, Depressive Symptomatology
Emotional Experiences in Fathers of NICU Infants
This study is designed to evaluate the emotional experiences of fathers who have preterm infants who are hospitalized in a (neonatal intensive care unit)NICU setting.
- Trial name
- NCT00306605
- Testing
- Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Pregnancies
Preterm Delivery Prevention in Twins With Progesterone
Twin pregnancies have very high preterm delivery rate. Until now, no RCT has proven benefit of progesterone in this population. In contrast, singleton pregnancies are treated with this hormone.
- Trial name
- NCT01927029
- Testing
- Progesterone
- Volunteers
- 213 people
- Sponsor
- Universidad del Desarrollo
Premature Birth
Assessment of the Behavior of the Preterm Newborns
The project presented here aims to evaluate the discrimination capacity of the Observation of Sensory-Motor Behavior (OSMB) grid of the preterm infant, as well as its predictive capacity for the child's later psychomotor…
- Trial name
- GOCSM (NCT05898295)
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Geneva
Preterm Birth, PPROM
Antenatal Breastmilk Expression in Pregnant Women at High Risk of Preterm Birth
In this randomized controlled study, the investigators aim to examine if antenatal breastmilk expression (aBME) from week 28 in high-risk pregnancies is a safe and effective method to ensure early access to mother's own milk.
- Conditions
- Preterm Birth, PPROM, Preeclampsia, Previous Preterm Birth
- Trial name
- EXPRESSMOM2 (NCT07191366)
- Testing
- Handstimulation of breast
- Volunteers
- 250 people
- Sponsor
- Odense University Hospital
Third Stage of Labor
Homeopathic Remedy for the Third Stage of Delivery
The homeopathic remedy consisting of Arnica and Bellis perennis have been shown in a previous pilot study (n=33) to reduce blood loss during the third stage of delivery, when compared with placebo treatment.
- Trial name
- NCT01156194
- Testing
- Homeopathy 1, Homeopathy 2
- Where
- Israel
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Preterm Birth
Comparison of Non-nutritive Suck (NNS) Measures to Clinical Estimates of Suck and Feeding Readiness in Preterm Infants
This is a research study to quantitatively assess the development of non-nutritive suck (NNS) and feeding readiness in preterm infants using a novel device, the NTrainer©, and to compare this with two clinical assessment tools…
- Trial name
- NCT01069731
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- KC BioMediX, Inc
Labor Pain
Transcutaneous Electrical Nerve Stimulation for Labor Pain Control
Transcutaneous electrical nerve stimulation (TENS) is a non-invasive electro-physical modality used for several pain conditions including labor pain control.
- Trial name
- NCT04894539
- Testing
- DS5 electrical stimulator
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Premature Birth
Oxidative Stress in Women Treated With Atosiban for Impending Preterm Birth
Oxidative stress is recognized as a important factor in the pathogenesis premature birth. Preterm birth is defined as delivery before 37 completed weeks of gestation and it is the leading cause of neonatal morbidity and…
- Trial name
- NCT03570294
- Testing
- Atosiban
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Anxiety Fear, Prenatal Depression
Mentors Offering Maternal Support (M-O-M-S™): A Prenatal Program for Decreasing Maternal Anxiety and Depression
The M-O-M-S project evaluates the effectiveness of the M-O-M-S program for improving birth outcomes and maternal-infant attachment and role satisfaction in a large military sample.
- Conditions
- Anxiety Fear, Prenatal Depression, Infant, Low Birth Weight, Preterm Birth
- Trial name
- M-O-M-S (NCT03393637)
- Testing
- Mentors Offering Maternal Support (M-O-M-S)
- Where
- 3 sites in United States
- Volunteers
- 1,717 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Preeclampsia, Preterm Birth
Pregnancy Complications - A Probiotic Interventional Study
Investigators hypothesize that a) probiotics decrease the overall inflammatory state in the pregnant woman, especially in women with high risk pregnancies.
- Trial name
- NCT02693041
- Testing
- probiotic
- Where
- Sweden
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Pregnancy Complications, Preterm Birth
Group Antenatal/Postnatal Care in Rwanda
The focus of this work is to improve antenatal care (ANC) and postnatal care (PNC) at the health center level in five districts in Rwanda (Bugesera, Burera, Nyamasheke, Nyarugenge, and Rubavu).
- Conditions
- Pregnancy Complications, Preterm Birth, Preterm Labor, Stillbirth
- Trial name
- PTBi Rwanda (NCT03154177)
- Testing
- Group ANC/PNC, Ultrasound+Pregnancy Testing
- Where
- 2 sites in Rwanda
- Volunteers
- 26,381 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Labor Pain, Tocophobia
Prenatal Education About Reducing Labor Stress (PEARLS)
The purpose of this small randomized controlled trial (RCT) is to compare the impact of a brief (16 hour) 3rd trimester mindfulness-based childbirth education program, "Mind in Labor (MIL): Working with Pain in Childbirth," with…
- Trial name
- PEARLS (NCT02327559)
- Testing
- Mind in Labor (MIL): Working with Pain in Childbirth, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infant Growth, Mothers' Parental Competence
Nursing and Nurturing Premature Infants
The purpose of this study is to determine whether systematic use of the Newborn Individualized Developmental Care Assessment Program (NIDCAP®) improves the neurologic development of children and the parental competence of mothers.
- Trial name
- NCT00388141
- Testing
- NIDCAP
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Cerebral Disorders Congenital, Premature Birth
Italian Survey on Paediatric and Neonatal MRI
Paediatric anaesthesia care in the Magnetic Resonance Imaging is a challenge for clinicians. The recent debate about the role of anaesthetic agent on neural development, encouraged an evaluation of their actual activity in this…
- Trial name
- NCT04775641
- Testing
- questionnaire
- Where
- Italy
- Volunteers
- 876 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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