Clinical trials: Labor Epidural Analgesia
Pregnancy, Pain
Safety of Epidural Fentanyl and Adrenalin During Childbirth
Investigation of pharmacokinetic effects of combining fentanyl and adrenalin in the epidural solution given to women in childbirth
- Trial name
- NCT00685672
- Testing
- adrenalin
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Labor Pain
The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia
The purpose of this study is to determine the ideal dosage of intrathecal morphine for intra and post partum analgesia, while minimizing the side effect profile.
- Trial name
- NCT01146457
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hypotension, Labor Complication
Leg Elevation to Prevent Hypotension During Labor
When hypotension is related to epidural placement, this can occur within 15-60 minutes after placement. The purpose of this study is to build upon this preliminary work and to use a randomized controlled trial to examine the…
- Trial name
- NCT05674838
- Testing
- Leg Elevation
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Labor, Epidural Analgesia
Effect of Epidural Analgesia on the Length of Labor and Delivery and Fetal Outcomes
The purpose of this study is to determine if there is a difference in the duration of the first and second stage of labor in nulliparous women , with or without epidural analgesia.
- Conditions
- Labor, Epidural Analgesia, Nulliparous
- Trial name
- NCT02396563
- Testing
- epidural analgesia, Ropivacaine
- Volunteers
- 100 people
- Sponsor
- University of Cagliari
Uterine Contraction, Oxytocin
The Influence of Oxytocin on Intrapartum Fetal Well-being and Delivery Outcomes in Patients Receiving Epidural Analgesia
The aim of this study is to determine the influence of oxytocin on fetal well-being during labor in patients receiving epidural analgesia (ELA) with the use of cardiotocography (CTG) and doppler ultrasonography.
- Conditions
- Uterine Contraction, Oxytocin, Labor Progress, Fetal Doppler
- Trial name
- NCT06403982
- Testing
- Continuation of oxytocin after ELA, Discontinuation of oxytocin after ELA
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Analgesia in Labor
Erector Spinae Plane Block Versus Classic Epidural Analgesia in Labor
Prosepective,Randomized, controlled study enrolling full termed parturients admitted for vaginal delivery. At the sencond stage of labor: 3cm of cervix dilatation, patients will be randomized in 2 groups: ESP group: patients will…
- Trial name
- NCT04776512
- Testing
- ESP Block With Bupivacain, Epidural Analgesia
- Volunteers
- 50 people
- Sponsor
- Mongi Slim Hospital
Analgesia, Labor Pain
Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor Analgesia
The purpose of this study is to compare the effects of three different doses of hydromorphone combined with ropivacaine and sufentanil combined with ropivacaine in epidural labor analgesia through prospective clinical trials, so…
- Trial name
- NCT05901441
- Testing
- Hydromorphone, Sufentanil, Ropivacaine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Labor Analgesia
Neuroaxial Labour Analgesia
The primary outcome of this clinical trial is to compare the pain scores during labour and delivery of combined spinal epidural without intrathecal opioids and dural puncture epidural The secondary objective of this study is to…
- Trial name
- NCT03980951
- Testing
- Dural Puncture Epidural Technique, Combined Spinal Epidural without intrathecal opioids, epidural
- Where
- 2 sites in Egypt, Kuwait
- Volunteers
- 120 people
- Sponsor
- Wahba bakhet
Labor Pain
Optimum Length of Catheter in the Epidural Space for Labor Analgesia in Non-obese Women: a Randomised Controlled Trial of 4 cm Versus 5 cm
Epidural analgesia was introduced to the world of obstetrics in 1909 by Walter Stoeckel. Over the following 100 years it has developed to become the gold-standard for delivery of intra-partum analgesia, with between 60 and 75% of…
- Trial name
- NCT04946032
- Testing
- Epidural catheter
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Effects of; Anesthesia, in Labor and Delivery
Intrathecal Dexamethasone and Labor Analgesia
To evaluate the effectiveness of adding dexamethasone to intrathecal levobupivacaine in combined spinal epidural (CSE) analgesia during vaginal delivery.
- Trial name
- NCT02588417
- Testing
- Dexamethasone, Levobupivacaine
- Volunteers
- 80 people
- Sponsor
- ahmed elsakka
Fetal Bradycardia, Hypertonic Uterine
Plasmatic Catecholamines: Randomized Controlled Trial Comparing Epidural Versus Combined Spinal-epidural
Combined spinal-epidural (CSE) for labor analgesia has been associated with fetal bradycardia and uterine hypertonia, possibly due to asymmetric decrease in catecholamine levels, when compared with epidural analgesia (EP).
- Conditions
- Fetal Bradycardia, Hypertonic Uterine, Catecholamines
- Trial name
- NCT02666794
- Testing
- Epidural bupivacaine with vasoconstrictor 0.125%, Epidural sufentanil, Placement of the epidural catheter
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Labor Pain
Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement
Labor pain is a major factor in making the placement of an epidural catheter difficult. The epidural, once in place and dosed, eventually decreases the parturient's pain.
- Trial name
- NCT01651962
- Testing
- Terbutaline, Fentanyl, 0.9% NaCl
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Kai Schoenhage
Vaginal Delivery
The Effects of Combined Spinal Epidurals on Fever During Labor of First-Time Mothers
The purpose of this study is to determine if the epidural of local anesthetics has an effect on fever that may occur in first time mothers during labor.
- Trial name
- CSE (NCT00802646)
- Testing
- saline, fentanyl/bupivacaine/epinephrine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Labor Pain
Programmed Intermittent Epidural Bolus For Laboring Obstetrical Women
Comparison of three programmed intermittent epidural bolus (PIEB) pump settings for maintenance of labour analgesia.
- Trial name
- NCT03712735
- Testing
- Bupivacaine 0.08% - fentanyl 2mcg
- Where
- Canada
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain, Breastfeeding
The Effect of Neuraxial Analgesia on Maternal Breastfeeding
A previous randomized trial showed a possible negative association with labor neuraxial analgesia with high compared to low doses of fentanyl, and breastfeeding at 6 weeks postpartum.
- Trial name
- NCT01074190
- Testing
- Group 1, Group 2, Group 3
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Labor Pain, Labor Analgesia
Combined Implementation of Dural Puncture Epidural and Programmed Intermittent Epidural Bolus for Labor Analgesia
This study intends to carry out a prospective, randomized double-blind study to evaluate the safety and efficacy of the combined implementation of Dural puncture epidural (DPE) technique and Programmed intermittent epidural bolus…
- Trial name
- NCT03366935
- Testing
- EPL and CEI, DPE and CEI, DPE and PIEB
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai First Maternity and Infant Hospital
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postpartum Depression
Effects of Epidural Labor Analgesia With Esketamine on the Incidence of Postpartum Depression in Parturients
Postpartum depression is a common psychological abnormality during the puerperium, which seriously affects maternal and neonatal health.
- Trial name
- NCT05826327
- Testing
- Esketamine, Sufentanil
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University