Clinical trials: Labor Induction
Labor, Induced, Cervical Ripening
Labor Induction With a Combined Method (Pharmacologic and Mechanical): Randomized Controlled Trial
Labor induction is a common pregnancy procedure worldwide. Both mechanical and pharmacologic agents are used for induction of labor. These agents reduce the incidence of cesarean delivery in women undergoing induction.
- Trial name
- NCT03928600
- Testing
- Cervical Foley combined with Misoprostol, Dinoprostone 10mg insert OR, Misoprostol
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Prelabour Rupture of Membranes at Term
A Pilot RCT on the Management of Term Prelabour Rupture of Membranes
This is a pilot study that will eventually result in a main randomised controlled trial that will look at what management is associated with a higher rate of normal birth and a lower rate of chorioamnionitis (maternal infection)…
- Trial name
- NCT02872883
- Testing
- Expectant management, Minimal Vaginal examinations (only when necessary), Active management
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Tobacco Use Disorder
Working Memory Training Combined With Transcranial Magnetic Stimulation in Smokers
Smoking remains the leading cause of preventable death in the United States, and current first-line treatments leave the majority of tobacco dependent individuals unable to quit.
- Trial name
- NCT03337113
- Testing
- Working Memory Training, repetitive Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kent State University
Cervical Ripening and Induction of Labor
Comparison Between Vaginal Misoprostol Gel and Oral Misoprostol Solution in Induction of Labor
The goal of this clinical trial is to study the efficacy of vaginal versus oral misoprostol solution in cervical ripening for induction of labor.
- Trial name
- NCT06874049
- Testing
- Vaginal misoprostol, Oral misoprostol solution (OMS)
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hagar Muhammad Abdulfattah Muhammad
Labor; Forced or Induced, Affecting Fetus or Newborn
The Comparison of Oxytocin Induced Labor and Cook Balloon Induced Labor
Currently, the study about intervention on the induced abortion at trimester is so little. So, the investigators want to compare the safety and effectiveness of different induced labor.
- Trial name
- NCT02202083
- Testing
- Cook Balloon
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Exercise-Induced Circulating Progenitor Cell Mobilization
Exercise Intensity and Circulating CD34+ Progenitor Cell Mobilization in Trained Adults
This randomized crossover study investigated whether exercise intensity influences the mobilization of circulating CD34+ progenitor cells when total external work is matched.
- Trial name
- NCT07841561
- Testing
- Higher-Intensity Work-Matched Cycling Exercise, Lower-Intensity Work-Matched Cycling Exercise
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samarra University
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Induction of Labor
Induction of Labor by Oral Misoprostol Solution
AIM: To evaluate effectiveness and safety of titrated oral misoprostol solution (OMS) in comparison with static-dose oral misoprostol solution for induction of labor at term.
- Trial name
- OMS (NCT04891679)
- Testing
- Oral misoprostol solution (OMS)
- Where
- India
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Labor Onset and Length Abnormalities
Effect Mobility During Induction of Labor on Time to Delivery. A Randomized Controlled Trial
this is a andomized controlled trial the evaluates the effect of enhanced mobility, controlled via electronic pedometers, during induction of labor by extra amniotic balloon on time to delivery.
- Trial name
- NCT03784092
- Testing
- feedback
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Intemittant, Continue, Oxytocin
Continuous Versus Intermittent Oxytocin for Induction of Labor: A Randomized Study
This study evaluates continuous oxytocin versus intermittent oxytocin for induction of labor at term. Half of participants will be taken continuous oxytocin, while the other half will be taken intermittent oxytocin.
- Trial name
- NCT02859571
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Cannabis Use Disorder, Cannabis Dependence
N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms
This study investigates the effects of repeated NAC administration on glutamate concentrations in the anterior cingulate cortex (ACC), on neurocognitive functioning, and on neuro-inflammatory parameters in adult…
- Trial name
- NCT03221231
- Testing
- N-acetylcysteine, Magnetic Resonance Imaging, Neurocognitive measures
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Induced Vaginal Delivery
Newborn Pain and Stress Levels in Oxytocin Induction at Birth
The aim of the study is to compare pain and stress levels in the early neonatal period in newborns with and without oxytocin induction. The research was conducted in a case-control study design.
- Trial name
- NCT06474000
- Testing
- Oxytocin induction group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Premature Birth, Obstructive Lung Disease
Pulmonary Outcomes of Bronchopulmonary Dysplasia in Young Adulthood
Preterm birth alters the normal sequence of lung development with lasting respiratory consequences. It is still unclear whether observed respiratory morbidities in preterm born individuals reflect sequelae from a non-progressive…
- Conditions
- Premature Birth, Obstructive Lung Disease, Bronchopulmonary Dysplasia
- Trial name
- NCT02820818
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Poor; Labor
The Effect of Coadministration of Oral Propranolol to Oxytocin on Induction of Labor
The effect of coadministration of oral propranolol to oxytocin on induction of labor.
- Trial name
- NCT02702674
- Testing
- propranolol, Oxytocin
- Where
- Egypt
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Anesthesia, Epidural, Hypotension
Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension
The purpose of this pilot trial is to examine the feasibility and ease of use of monitoring by ClearSight in laboring and delivering patients with the intent to compare time-to-treatment of hypotension between conventionally…
- Trial name
- NCT05906368
- Testing
- ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Obstetric Labour, Premature
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Retosiban (GSK221149) When Dosed With Efavirenz (EFZ)
This will be a randomized single sequence open label study. This study is designed to determine if chronic dosing with efavirenz (EFZ) will have an effect on the pharmacokinetics (PK) of intravenously-administered retosiban in…
- Trial name
- NCT01867996
- Testing
- Retosiban, EFZ 600 mg
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Premature Rupture of Membranes
FOLCROM Trial: Foley Catheter in Rupture of Membranes
Multicenter randomized clinical trial comparing oxytocin versus oxytocin and foley catheter for induction in women who present with premature rupture of membranes who are not in labor.
- Trial name
- FOLCROM (NCT01973036)
- Testing
- Foley Catheter, Oxytocin
- Where
- 5 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Induction of Labor
Cervical Ripening Balloon for 12 Hours vs. 1 Hour.
The aim of this study is a comparison of induction of labor with a cervical ripening balloon left in place for one hour compared to twelve hours. The primary outcome is time to delivery.
- Trial name
- NCT05922111
- Testing
- cervical ripening balloon for one hour, cervical ripening balloon for twelve hours
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus