Clinical trials: Labor and Delivery Complication
Feeding Disorder, Nutrition Disorder
Use of Prokinetics in Early Enteral Feeding in Preterm Infants
Objective of this study are: 1) To determine if medication help extreme preterm infants to tolerate feeding better by reaching full feeding earlier.2) Out of two medication; which one is better for efficacy 1) Erythromycin 2)…
- Conditions
- Feeding Disorder, Nutrition Disorder, Infant,Premature
- Trial name
- NCT01569633
- Testing
- Metclopramide, Erythromycin
- Where
- United States
- Sponsor
- East Tennessee State University
Ventilation
Neurally Adjusted Ventilatory Assist (NAVA) in Ventilatory Care of Premature Infants
The purpose of this study is to find out, whether it is possible to improve the ventilatory care of premature infants by using Neurally adjusted ventilatory assist (NAVA).
- Trial name
- NCT01156467
- Testing
- Neurally adjusted ventilatory assist, i-Servo, Maquet Nordic (Solna, Sweden), Control group, ventilation with i-Servo or Stephanie
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Oulu
Perinatal Mortality, Stillbirth
Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality
The purpose of this study is to determine whether a daily prenatal supplement of iron plus folic acid or a daily prenatal supplement with multiple vitamins and minerals given to women from their first prenatal visit through…
- Conditions
- Perinatal Mortality, Stillbirth, Neonatal Mortality
- Trial name
- NCT00133744
- Testing
- folic acid, folic acid plus iron, supplements with multiple vitamins and minerals
- Where
- 5 sites in China
- Volunteers
- 18,962 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Preterm Birth
Music Intervention for Preterm Birth
This study will test a music intervention (MI) versus a sham control (SC) arm which only includes a verbal intervention, to determine if the effects of the music intervention will reduce the biological impact of chronic stress…
- Trial name
- NCT05945264
- Testing
- Music Intervention (MI)
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Columbia University
Birth Outcome, Adverse, Labor Long
How Long Can Labor Last? Person Centred Care During Labor to Increase Safety for Women and Newborn
"How long will my labor last" is a very common question for midwives who care for women during birth. To evaluate safe labor duration largely determines management and care during birth.
- Conditions
- Birth Outcome, Adverse, Labor Long, Labor Complication, Maternal Injury
- Trial name
- NCT06420453
- Where
- Sweden
- Volunteers
- 300,000 people
- Sponsor
- Karolinska Institutet
Ophthalmic Artery, Labor and Delivery
The Ophthalmic Artery Doppler Evaluation Prior to Labor Induction and Adverse Intrapartum Fetal Outcomes
The ophthalmic artery Doppler has been recently proposed as a potential "soft marker" for placental insufficiency in retrospective and observational studies, with similar clinical significance with respect to Uterine Artery (UA)…
- Conditions
- Ophthalmic Artery, Labor and Delivery, Induction of Labor, Intrapartum Fetal Distress
- Trial name
- OPHELIA (NCT07846137)
- Testing
- Ophthalmic Artery Doppler
- Where
- Italy
- Volunteers
- 1,477 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Preterm Delivery, Preterm Birth
fFN & E3 in the Prediction of PTB in Women With Twin Pregnancies Receiving 17OHP or Placebo
Among women with a twin pregnancy, currently enrolled in a study in which they are receiving weekly injections of 17-alpha-hydroxyprogesterone caproate verses placebo injections, fetal fibronectin (fFN) and salivary estriol (E3 )…
- Trial name
- NCT00156000
- Testing
- Fetal Fibronectin, Salivary Estriol
- Where
- 2 sites in United States
- Sponsor
- Obstetrix Medical Group
Pre-Eclampsia Onset Less Than 37 Weeks, Pre-Eclampsia
Preeclampsia Intervention Netherlands
The goal of this study is to find out if pregnant individuals with preterm preeclampsia (PE) who are treated with metformin can stay pregnant for longer, and if this is safe(r) for the mother and child.
- Conditions
- Pre-Eclampsia Onset Less Than 37 Weeks, Pre-Eclampsia, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia as Antepartum Condition
- Trial name
- PI-NL (NCT06452498)
- Testing
- Metformin Hydrochloride
- Volunteers
- 180 people
- Sponsor
- Amsterdam UMC
Episiotomy Wound
Comparison Between Lidocaine Prilocaine Cream and Lidocaine Injection on Pain Control During Episiotomy.
The present study aims to compare the effects of lidocaine-prilocaine cream and lidocaine injection on the reduction of pain while doing and repairing episiotomy, controlling the pain in the post-partum period, and reduction the…
- Trial name
- NCT05891132
- Testing
- 10 ml of lidocaine 2%, lidocaine prilocaine cream 15gm
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Preterm Birth, Preterm Premature Rupture of Membrane
Amniochorionic Membrane Cells in the Maternal Blood as a Biomarker for Preterm Birth
Globally, preterm birth (15 mill. per year) is the leading cause of under-5 child mortality (1 mill. per year) and morbidity. Important pathways include preterm labor contractions, Preterm Prelabor Rupture of the Fetal Membranes…
- Conditions
- Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Labor
- Trial name
- NCT04705935
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obstetric Labour, Premature
The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor
Pre-Term Labor (prior to 37 weeks gestation) is the largest single cause of infant morbidity and mortality and is frequently associated with long-term disability. Oxytocin is a hormone produced by the body during labor.
- Trial name
- NCT00404768
- Testing
- GSK221149A
- Where
- 57 sites in United States, Argentina and 9 more
- Volunteers
- 93 people
- Sponsor
- GlaxoSmithKline
Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia
Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS)
Bronchopulmonary Dysplasia (BPD) is a multi-factorial disease process that is the end result of an immature, surfactant deficient lung that has been exposed to hyperoxia, mechanical ventilation and infection.
- Trial name
- NCT01473264
- Testing
- recombinant human CC10 (rhCC10)
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Clarassance, Inc.
Infants in NICU Ventilated With HFV
Capnography in Infants Ventilated With High Frequency Ventilation
The investigators hypothesize that dEtCO2 measured by the Microstream® technique via a double-lumen ETT in infants ventilated with HFV would be feasible and adequately represent the arterial CO2 (PaCO2).
- Trial name
- NCT00859209
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Bnai Zion Medical Center
Premature Infant
A Study of Family-integrated Care for Reducing Uncertainty
To explore the intervention effect of family participatory nursing on the uncertainty of illness of parents of hospitalized premature infants, and to evaluate the uncertainty level of parents of premature infants in different…
- Trial name
- NCT04648787
- Testing
- family-integrated care, traditional nursing
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Children's Hospital of Fudan University
Premature Birth, Risk
The Effect of the Movement Imitation Therapy in Preterm (MIT-PB) in Motor Behavior's Quality.
This study aims to assess the effect of a parent-administered intervention program based on MIT-PB in preterm with abnormal general movements during the preterm period.
- Conditions
- Premature Birth, Risk, Early Intervention
- Trial name
- MIT-PB (NCT05319158)
- Testing
- MIT-PB, movement imitation therapy for preterm.
- Where
- 3 sites in Spain
- Volunteers
- 36 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Infant, Premature
Preliminary Study to the Conception of a Non-invasive Neonatal Monitoring System With Development of a Database
Each year, 300 000 new borns are hospitalised in neonatology units in Europe. This period is very sensitive as newborns are exposed to a high risk of morbidity and mortality, with severe impact on neuro-developmental prognostic.
- Trial name
- Digi-NewB (NCT02863978)
- Testing
- Multimodal signal acquisitions
- Where
- 6 sites in France
- Volunteers
- 746 people
- Sponsor
- Rennes University Hospital
Premature Birth, Extremely Premature Infants
Prenatal Counseling in Extreme Prematurity: Professionals' View
This study is part of the PreCo study, evaluating Dutch care in (imminent) extreme preterm birth including current and preferred counseling, barriers and facilitators for preferred counseling from both obstetricians and…
- Trial name
- PreCo-profs (NCT02782650)
- Testing
- survey and interview
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Nosocomial Infections, Sepsis
Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
The purpose of this study is to show whether Veronate, a donor-selected staphylococcal human immune globulin intravenous (IGIV), can prevent an infection in the blood caused by staphylococcal bacteria in premature babies weighing…
- Conditions
- Nosocomial Infections, Sepsis, Staphylococcal Infections, Candidemia
- Trial name
- NCT00113191
- Testing
- Veronate
- Where
- 93 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Bristol-Myers Squibb
Premature Birth, Premature Labor
Treatment of Preterm Labor With 17 Alpha-hydroxyprogesterone Caproate
The goal of our research will be to determine the effectiveness of 17 alpha-hydroxyprogesterone caproate (17P) in the treatment of preterm delivery.
- Trial name
- NCT00120640
- Testing
- 17 hydroxyprogesterone caproate intramuscular injections
- Sponsor
- Yale University
Pre-Term
Citicoline as Neuroprotector in Preterm
Citicoline as neuroprotector in preterm
- Trial name
- NCT03966170
- Testing
- Citicoline
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherief Abd-Elsalam
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