Clinical trials: Laboratory Testing, active
Pediatric Sleep Disordered Breathing, Obstructive Sleep Apnea
Pediatric/Adolescent WatchPAT 400 Reliability Pilot Study
The goal of this clinical trial is to learn whether a newer sleep-testing device gives results that closely match the standard overnight sleep study, in children and adolescents ages 6-18 who are being evaluated for possible…
- Trial name
- NCT07851402
- Testing
- WatchPAT 400
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Milton S. Hershey Medical Center
Urinary Tract Stones
Multicenter Study to Develop a Model to Identify Uric Acid Urinary Tract Stones Using CT and Lab Tests
Urinary tract stones are a common condition affecting the kidney, ureter, bladder, and urethra. Uric acid stones represent an important subtype of urinary stones and require different prevention and treatment strategies compared…
- Trial name
- UAS-Model (NCT07328932)
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 1,650 people
- Sponsor
- Jian Zhuo
Hyperpalatable Foods, Abuse Liability
Testing the Abuse Liability of Hyper-palatable Foods
The study will conduct a laboratory study designed to evaluate the rewarding and addictive properties of hyper-palatable foods (HPF), using potato chips as the food stimulus/sample HPF.
- Trial name
- NCT07776938
- Testing
- Full Dose HPF, Modified Dose- No Fat, Modified Dose- No Sodium
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Hospital Acquired Condition
Re-Purposing the Ordering of Routine Laboratory Tests in Hospitals in British Columbia
The goal of this stepped-wedge cluster randomized trial is to assess the impact of a laboratory test overuse intervention bundle on laboratory test utilization in 6 health authorities (16 hospitals) in British Columbia.
- Trial name
- RePORT-BC (NCT06359587)
- Testing
- Laboratory test overuse (LTO) Bundle
- Where
- 4 sites in Canada
- Volunteers
- 700,000 people
- Sponsor
- University of British Columbia
Chronic Kidney Disease (CKD), Health Communication
Patient-centered Precision Medicine Lab Result Communication for Older Adults
For adults ≥65 years and their providers, the investigators will test the usability and design of a tool to replace standard uniform reporting of lab results to patients and their providers with a new personalized Electronic…
- Conditions
- Chronic Kidney Disease (CKD), Health Communication, Patient Comprehension
- Trial name
- NCT07391904
- Testing
- Chronic Kidney Disease (CKD) Lab Result Communication Tool
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- University of California, Los Angeles
Utilization, Health Care
Re-Purposing the Ordering of 'Routine' Laboratory Tests in Hospitalized Medical Patients (RePORT Study)
Laboratory test overuse occurs when tests are ordered repetitively, without due consideration of impact on clinical status. Repetitive inpatient lab testing often provides limited value for patient outcomes while increasing…
- Trial name
- NCT06119464
- Testing
- Multimodal Intervention: Education, Multimodal Intervention: Audit and Feedback, Multimodal Intervention: Patient Engagement
- Where
- Canada
- Volunteers
- 251,817 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Sleep Apnea, Obstructive, Sleep Disorder
Home Apnea Testing in CHildren Trial
This clinical trial will compare home sleep apnea testing with the gold standard in-lab polysomnography in terms of 1) accuracy, 2) therapeutic decision-making, and 3) parent/child acceptability in children referred for…
- Conditions
- Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
- Trial name
- HATCH (NCT05382754)
- Testing
- Home sleep apnea test, In-lab polysomnography
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Children's Hospital of Philadelphia
Lung Cancer, Surgery
Development and Clinical Validation of Early-stage Lung Cancer Prognostic Kit
Lung cancer is the leading cause of cancer mortality worldwide in spite of the advanced progresses in medication and low-dose CT screening.
- Conditions
- Lung Cancer, Surgery, Recurrence
- Trial name
- NCT05557474
- Testing
- Early-stage lung cancer prognostic kit -- ELISA, Early-stage lung cancer prognostic kit -- IHC
- Where
- 2 sites in Taiwan
- Volunteers
- 236 people
- Sponsor
- Chung Shan Medical University
Diagnostic Techniques and Procedures, Clinical Laboratory Techniques
Clinical Validation of an Artificial Intelligence System for the Interpretation of Laboratory Test Results Combined With a Structured Medical History
This study evaluates a certified artificial intelligence (AI) based software system that automatically interprets laboratory test results in combination with a structured, dynamically generated medical history questionnaire.
- Conditions
- Diagnostic Techniques and Procedures, Clinical Laboratory Techniques, Triage
- Trial name
- LTC-VALID (NCT07810491)
- Testing
- AI-based laboratory result interpretation software
- Where
- 2 sites in Poland
- Volunteers
- 899 people
- Sponsor
- Labplus Sp. z o.o.
Acceptability of Health Care
Closed-blood Sampling Devices in the Adult Critically Ill Patient
Based on the hypothesis that the strategy of using Closed-Blood Sampling Devices (CSBD, experimental group) compared to the usual practice (waste discard volume, control group), in critically ill adult patients, will decrease the…
- Trial name
- NCT06478160
- Testing
- Closed-Blood Sampling Devices, Waste discard volume
- Where
- 3 sites in Spain
- Volunteers
- 216 people
- Sponsor
- University of Barcelona
Arthritis of Knee, Arthritis of Hip
Comparison of the Diagnosis Time of VET and SCL in Patients With Intraoperative Coagulopathy
The present study is a prospective, multi-center observational trial comparing the times taken to diagnose coagulopathies using point-of-care (POC) viscoelastic tests or standard central laboratory tests (SCL tests) in patients…
- Conditions
- Arthritis of Knee, Arthritis of Hip, Spine, Prostate Cancer
- Trial name
- NCT06637943
- Testing
- SCL tests, POC viscoelastic tests
- Where
- 4 sites in South Korea
- Volunteers
- 210 people
- Sponsor
- Konkuk University Medical Center
COVID-19, COVID
Clinical Validation of the Aptitude Medical Systems Metrix COVID-19 Test
The Metrix COVID Test will be evaluated for use in Point-of-Care and Non-Laboratory settings in a home testing environment utilizing the clinical study design described herein.
- Trial name
- NCT06744660
- Testing
- Aptitude Medical Systems Metrix COVID Test
- Where
- 3 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aptitude Medical Systems
OSA - Obstructive Sleep Apnea
Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea
The goal of this observational study is to compare predictive equations for continuous positive airway pressure (CPAP) with in-laboratory manual titration in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT07376343
- Testing
- Sleep test, Predictive equations of continuous positive airway pressure (CPAP)
- Where
- 2 sites in Thailand
- Volunteers
- 150 people
- Sponsor
- Thammasat University
Endometriosis
Multicenter Study for Diagnostic Validation of a Laboratory Test for the Diagnosis of Endometriosis
Endometriosis affects at least 1 in 10 women worldwide and is associated with a diagnostic delay of 5-10 years. Currently, definitive diagnosis requires invasive laparoscopy, which is costly and burdensome for patients.
- Trial name
- NCT07553676
- Where
- 8 sites in Austria, Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Diamens FlexCo
Acute Stress Reaction
The Efficacy of Vitamin D Supplementation to Sustain Performance Outcomes
The goal of this clinical trial is to find out if vitamin D supplements help healthy adults maintain their cognitive and simple physical task performance and emotional state during highly stressful situations.
- Trial name
- NCT07654777
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Thrombocytopenia, Platelet Transfusion
Role of Viscoelastometric Testing in the Development and Validation of a Clinical-biological Score for Predicting Bleeding in Patients With Malignant Haematological Disorders and Severe Thrombocytopenia
The goal of this single-center, non-controlled, non-randomized exploratory clinical trial is To develop and validate a clinical-biological score (VISCOTHEM score) incorporating viscoelastometric tests parameters; based on an…
- Conditions
- Thrombocytopenia, Platelet Transfusion, Haemorrhage, Hematologic Malignancies
- Trial name
- VISCOTHEM-2 (NCT07653672)
- Testing
- Additional blood sample
- Where
- France
- Volunteers
- 410 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Semen Analysis, Male Infertility
YO® Smartphone Home Sperm Test Versus Manual Semen Analysis in Egyptian Men
This study compares the YO® Home Sperm Test, a smartphone-based semen testing device, with conventional manual semen analysis performed according to the World Health Organization (WHO) 6th edition laboratory manual.
- Trial name
- NCT07880288
- Testing
- YO® Home Sperm Test, Manual Semen Analysis (WHO 6th Edition)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Armed Forces College of Medicine, Cairo, Egypt
Endometriosis, Diagnosis
Proof of Concept Study to Eval MetriDx Lab-developed Test to Identify Endometriosis-specific Bio Markers
This study is testing a way to diagnose endometriosis using a uterine tissue biopsy (similar to a pap smear) as opposed to undergoing laparoscopy surgery.
- Trial name
- NCT05698212
- Testing
- MetriDx
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Hera Biotech, Inc.
Hutchinson-Gilford Progeria Syndrome
Creating Stem Cells From a Progeria Patient's Blood to Test Candidate Treatments in the Lab
This study aims to establish induced pluripotent stem cell (iPSC) lines from the blood of one pediatric patient with Hutchinson-Gilford Progeria Syndrome (HGPS), a rare disease that causes rapid, premature aging, in order to…
- Trial name
- NCT07803432
- Volunteers
- 1 people
- Sponsor
- Bundang CHA Hospital
Obesity
Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL)
The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research…
- Trial name
- VAL (NCT06286761)
- Testing
- endothelial cell collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bettina Mittendorfer