Clinical trials: Labour
Labour Pain
Development of a Multi-attribute Health Index: to Measure the Quality of Labour Analgesia: The QLA Index
The findings of this research will be used to develop a scale for measuring the quality of epidural pain relief achieved during labour and vaginal delivery.
- Trial name
- NCT01177046
- Where
- Canada
- Volunteers
- 752 people
- Sponsor
- Sunnybrook Health Sciences Centre
Bladder Care
Women's Experiences of Maternity Bladder Care
Background. Although a healthy urinary system is a vital aspect in every woman's life, bladder management is an aspect of maternity care, which is, or perceived as, being poorly managed by health care professionals.
- Trial name
- NCT03084354
- Testing
- Semi-structured interviews
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Labour Analgesia
Role of the Single-shot Spinal Analgesia to Control Labour Pain
Labor pain is the most severe pain most women will endure in their lifetimes. The most complete and effective method of pain relief during childbirth is neuraxial labor analgesia which provides adequate analgesia without maternal…
- Trial name
- NCT02800694
- Testing
- "bupivacainediluted with 1 ml of normal saline" and "25 μg fentanyl "
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Minia University
Parturients in Labour
Alteration in Hearing Following Accidental Dural Puncture. A Study in Parturients
Headache following accidental dural punction as during epidural analgesia can be severe and sometimes very disabling. The incidence of PDPH is 10-40%, most starting within 48 h of dural puncture.
- Trial name
- AHEAD (NCT01682967)
- Where
- 2 sites in Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Obstetric Labour, Premature
The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor
Pre-Term Labor (prior to 37 weeks gestation) is the largest single cause of infant morbidity and mortality and is frequently associated with long-term disability. Oxytocin is a hormone produced by the body during labor.
- Trial name
- NCT00404768
- Testing
- GSK221149A
- Where
- 57 sites in United States, Argentina and 9 more
- Volunteers
- 93 people
- Sponsor
- GlaxoSmithKline
Pain
Bupivacaine, Levobupivacaine and Ropivacaine After Intrathecal and Extradural Injection in Labour
A need exists to define the best local anesthetic and technique for pain relief in early labour. We suggest that calculating the molar Median Effective Dose for bupivacaine, levobupivacaine and ropivacaine given both by the…
- Trial name
- NCT01201213
- Testing
- local anaesthetic injection
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- NHS Tayside
Retained Placenta
Intraumbilical Misoprostol in Retained Placenta
Administration of intraumbilical misoprostol to women with retained placenta despite active management of third stage of labour reduces the need for manual removal of placenta and the amount of blood loss vaginally.
- Trial name
- NCT01840813
- Testing
- Misoprostol, Normal saline
- Where
- Iraq
- Volunteers
- 46 people
- Sponsor
- Hawler Medical University
Labour Analgesia
Effect of Epidural Needle Injection on Catheter Placement Success During Painless Labour
Epidural analgesia is the gold standard for painless labour, but successful catheter placement can be technically challenging due to anatomical and physiological changes in pregnancy.
- Trial name
- NCT07327918
- Testing
- Injection Group, Control group
- Where
- Egypt
- Volunteers
- 216 people
- Sponsor
- Al-Azhar University
Mental Disorder
Improving Integration of Mentally Burdened Young Adults in the Labour Market
Young adults who do not successfully transition from compulsory education to upper secondary level are at increased risk of developing mental illness, as compared with their working peers.
- Trial name
- inklusiv (NCT03328286)
- Testing
- Weekly group meeting w/psychotherapist
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Labor Duration, Labor Bain
The Effect Of The Labour Hopscotch On The Birth Process And Satisfaction
This study is designed to evaluate the effect of the Labor Hopscotch exercise on the birth process and maternal satisfaction. The study will be conducted as a randomized controlled trial at a tertiary-level maternity unit.
- Conditions
- Labor Duration, Labor Bain, and Birth Satisfaction During Physiologic Vaginal Birth
- Trial name
- Labor Hopscotc (NCT07330557)
- Testing
- Labor Hopscotch Exercise Program Group, Standard Intrapartum Care
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Aydin Adnan Menderes University
Labour Pain
Programed Intermittent Epidural Bolus Interval 90 (EI90) of 10 ml, 0.0625% Bupivacaine Plus 2 μg/mL Fentanyl
Multiple studies showed the numerous advantages of implementing programmed epidural bolus (PIEB) technique, where a fixed volume of local anesthetic is automatically administrated at a set time interval compared to the continuous…
- Trial name
- NCT05441085
- Testing
- programed intermittent epidural bolus interval 90 (EI90)
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Pregnancy, Childbirth and the Puerperium
A Pilot Randomized Controlled Trial of Repeated Hands-and-Knees Positioning During Labour
The investigators designed a pilot randomized controlled trial to assess the feasibility and acceptability of repeated hands-and-knees positioning during labour.
- Trial name
- LPT2 (NCT01720004)
- Testing
- Repeated hands-and-knees positioning during labour
- Where
- 2 sites in United States, Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Post-Dural Puncture Headache
Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study
The purpose of this study is to determine the effect of 19g versus =>18g traditional Tuohy-type epidural needles on the incidence and severity of postdural puncture headache (PDPH).
- Trial name
- NCT00370604
- Testing
- 19g Tuohy-type epidural needle, 23g catheter, => 18g Tuohy-type needle
- Where
- 4 sites in Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Post Term Pregnancy, Premature Rupture of Membrane
Dilapan-S®: A Multicenter US E-registry
Objective of this registry is to collect a representative set of real world data on the use of Dilapan-S® for pre-induction cervical ripening in daily clinical practice.
- Conditions
- Post Term Pregnancy, Premature Rupture of Membrane, Fetal Growth Retardation, Oligohydramnios
- Trial name
- NCT04451109
- Testing
- Dilapan-S
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Medicem Technology s.r.o.
Failed Induction of Labor
Vaginal Estradiol Pretreatment in Labour Induction With Misoprostol
To assess the effect of vaginal estradiol pretreatment before vaginal misoprostol on labor induction.
- Trial name
- NCT02485821
- Testing
- Estradiol, Misoprostol
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Prolonged Labor
Electronic Partograph: A Way of Improving Partograph Use During Labour Monitoring Process in Selected District Hospitals in Bangladesh
Background (brief): 1. Burden: Abnormal prolonged labour and its effects are important contributors to maternal and perinatal mortality and morbidity worldwide.
- Trial name
- NCT03509103
- Testing
- Electronic Partograph
- Volunteers
- 1,012 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hospitalism
Emotional Labor, Physical Labor and Mental Labor of Hospice Care Nurses: A Mixed-method Study
Hospice care is a nurse-led multidisciplinary team care that provides physical, mental, and social care to end-of-life patients.
- Trial name
- NCT05608512
- Testing
- interview
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Labour Analgesia, Epidural Anaesthesia
Higher vs Lower Lumber Epidural Catheter Insertion During Labour: A Randomised Trial to Compare Efficacy.
This study will randomise pregnant women to labour epidural at a higher versus a lower lumbar level. Outcomes relating to success or failure of the epidural catheter at this level will be assessed.
- Trial name
- NCT06850636
- Testing
- Epidural Analgesia
- Where
- Ireland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- The Rotunda Hospital
Caesarean Section
Ropivacaine 0.75% Versus Levobupivacaine 0.5% for Conversion of Labour Epidural
The aim of this trial is to compare the local anaesthetic ropivacaine to local anaesthetic levobupivacaine in converting the standard patient controlled labour epidural to provide anaesthesia for an emergency Caesarean section.
- Trial name
- RoLe (NCT01160965)
- Testing
- 0.5% levobupivacaine, 0.75% Ropivacaine
- Where
- United Kingdom
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Caesarean Sections, Augmentation With Oxytocin
The Labour Progression Study, a Cluster Randomised Trial on Labour Progression for First Time Mothers
The purpose of this study is to evaluate if the rate of emergency caesarean section can be reduced if adhering to a dynamic labour progression curve compared to a static progression curve for first time mothers without…
- Conditions
- Caesarean Sections, Augmentation With Oxytocin, Labour Dystocia
- Trial name
- LAPS (NCT02221427)
- Testing
- Dynamic progression curve, Static labour progression curve (F)
- Where
- Norway
- Volunteers
- 6,582 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust