Clinical trials: Labour
Labor, Induced
'Extended Balloon Catheter' Labour Induction; a Single Arm Pilot Trial'
The overall aim of the single arm pilot study was to assess the effectiveness, safety and acceptance of the 'extended balloon catheter' as a method of induction of labour in women receiving care at Princess Marina Hospital(PMH)…
- Trial name
- NCT05885087
- Testing
- Foley or balloon catheter
- Where
- Botswana
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Botswana
Prelabor Rupture of Membranes
Impact of Early Rupture of the Residual Membrane on Latency Before Labour Begins
Approximately 25% of patients experience premature rupture of membranes before labour. Of these patients, 82% will give birth within 24 hours and 97% within 48 hours.
- Trial name
- RESIRUPT (NCT07301957)
- Testing
- Additional rupture of the residual membrane
- Where
- 2 sites in France
- Volunteers
- 130 people
- Sponsor
- Centre Hospitalier le Mans
Labor Pain
A Novel Approach to Optimize Programmed Intermittent Epidural Bolus (PIEB) Delivery for Labour Analgesia
Programmed intermittent epidural bolus (PIEB) for labour analgesia allows an epidural pump to be programmed to deliver small amounts of the local anesthetic and opioid solution at regularly timed intervals.
- Trial name
- NCT03871530
- Testing
- Coordinate A, Coordinate B, Coordinate C
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- IWK Health Centre
Pregnancy, Labour Onset and Length Abnormalities
Role of Maternal Physical Exercise on Spontaneous Labor Onset
Evaluate the effects of the practice of maternal physical exercise on the term of pregnancy as a method to enhance spontaneous labor.
- Trial name
- NCT02460185
- Testing
- Study group: Maternal Physical Exercise
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Norte
Obstetric; Injury Pelvic Floor
The Effect of Pregnancy and Labour on the Pelvic Floor Diagnosed With 3D and 4D Ultrasound
Injuries to the pelvic floor muscles and fascias during delivery and childbirth may lead to urinary incontinence (25-45 %), faecal incontinence (11-45%), pelvic organ prolapse (7-23%), sexual dysfunction (15-33 %) and chronic…
- Trial name
- NCT01045135
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
HIV Infections
Efficacy of Nevirapine Compared to ZDV + 3TC Administered in Labor and Again at Postdelivery in HIV Positive Women
The primary objective of the study was to evaluate the efficacy of nevirapine versus ZDV+3TC (Zidovudine + Lamivudine), when administered in labor and again at postdelivery, in reducing peripartum mother to child transmission of…
- Trial name
- NCT02181933
- Testing
- Nevirapine, Zidovudine (ZDV), Lamivudine (3TC)
- Volunteers
- 2,648 people
- Sponsor
- Boehringer Ingelheim
Preterm Labour
N-Acetyl Cysteine for Prevention of Preterm Birth
The antioxidant effect of N-Acetyl cysteine can abort the inflammatory cascade responsible for initiation of preterm labour especially among patients with reccurent preterm birth and patients having bacterial vaginosis
- Trial name
- NAC (NCT00568113)
- Testing
- acetylcysteine in arm 1
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fetal Intrauterine Distress First Noted During Labor and or Delivery in Liveborn Infant, Team Based on Their Existing Guidelines and the Woman Consents to Have EFM and EFM is
Use of Decision Support in the Management of Labour
In women judged to require continuous electronic fetal heart rate monitoring (EFM) during their labour, does the addition of decision support software to aid the interpretation of the intrapartum cardiotocogram (CTG) reduce the…
- Conditions
- Fetal Intrauterine Distress First Noted During Labor and or Delivery in Liveborn Infant, Team Based on Their Existing Guidelines and the Woman Consents to Have EFM and EFM is, Possible
- Trial name
- INFANT (NCT02010710)
- Testing
- INFANT software
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 47,062 people
- Sponsor
- University College, London
Postpartum Bleeding
When and How to Administer Oxytocin for Active Management of Third Stage of Labour
To compare the efficacy of the route and timing of oxytocin administration for Active management of third stage of labour (AMTSL).
- Trial name
- NCT01954186
- Testing
- intravenous & intramuscular oxytocin, after delivery of the fetus & when anterior shoulder seen
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Etlik Zubeyde Hanim Womens' Health and Teaching Hospital
Adverse Reaction to Oxytocin
Continued Versus Discontinued Oxytocin Stimulation of Labour
Background: The proposed study will investigate the effect of Syntocinon® (synthetic oxytocin) to induce labour. The hypothesis to be studied is that once the active phase of labour has commenced, Syntocinon® can be discontinued…
- Trial name
- CONDISOX (NCT02553226)
- Testing
- Oxytocin
- Where
- 10 sites in Denmark, Netherlands
- Volunteers
- 1,200 people
- Sponsor
- University of Aarhus
Labour Pain, Midwifery
The Effect of Hand Exercise Hoops on Labour Pain
This randomized, single-blind controlled trial aims to evaluate the effect of using a hand exercise ring combined with breathing exercises on labor pain, anxiety, and childbirth satisfaction in primiparous women during the active…
- Trial name
- NCT07378449
- Testing
- Hand Exercise Hoop
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Occupational Health, Sick Leave
Effects of Regulatory Tools on Work Environment and Employee Health
This study evaluates the effects of the Labour Inspection Authority's regulatory tools on workplace exposures to prevent employee ill health.
- Conditions
- Occupational Health, Sick Leave, Occupational Exposure
- Trial name
- NCT03855163
- Testing
- Inspection visits, Guidance workshops, Online risk assessment tool
- Where
- 130 sites in Norway
- Volunteers
- 2,555 people, healthy volunteers welcome
- Sponsor
- National Institute of Occupational Health, Norway
Pregnancy, Prolonged, Induced; Birth
Membrane Sweeping to Prevent Post-term Pregnancy: The MILO Study
Multicentre, pragmatic, parallel group, pilot randomised controlled trial with an embedded factorial design.
- Conditions
- Pregnancy, Prolonged, Induced; Birth, Pregnancy Related
- Trial name
- MILO (NCT04307199)
- Testing
- Amniotic membrane sweep
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Arrested Labor
Bicarbonate Given During Dystocic Labor
Dystocic deliveries and the use of bicarbonate
- Trial name
- NCT02805387
- Testing
- Treatment
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Pregnant Women
Outpatient Induction of Labour Using a Double Balloon Transcervical Catheter in Low-risk Pregnant Women: a Two-centre Open Prospective Randomised Controlled Trial - OutCRIB
The aim goal of this study is to compare the duration of induction and labor between outpatient and inpatient care in low-risk pregnant women.
- Trial name
- OutCRIB (NCT07265518)
- Testing
- Outpatient, Inpatient
- Where
- 2 sites in France
- Volunteers
- 258 people
- Sponsor
- Nantes University Hospital
Labor Long
The Effect of Hyoscine-N-butylbromide (HBB, Buscopan) in Augmented Labour Among Primigravidae
This study compares the duration of active phase of labour in women who received buscopan and those who don't.
- Trial name
- NCT04349722
- Testing
- Hyoscine Butylbromide
- Where
- Malaysia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Pain During Labour
Tramadol for Labour Analgesia in Low Risk Primiparous Women
Tramadol is a centrally acting synthetic analgesic used to treat moderate to moderately severe pain. It has been previously evaluated as a method to reduce pain during labour, but there is always some fear related to its effects…
- Trial name
- NCT01889979
- Testing
- Tramadol
- Where
- Panama
- Volunteers
- 100 people
- Sponsor
- Saint Thomas Hospital, Panama
Mental Disorder
Improving Integration of Mentally Burdened Young Adults in the Labour Market
Young adults who do not successfully transition from compulsory education to upper secondary level are at increased risk of developing mental illness, as compared with their working peers.
- Trial name
- inklusiv (NCT03328286)
- Testing
- Weekly group meeting w/psychotherapist
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Induction of Labour With Misoprostol
Comparison of Oral Versus Vaginal Misoprostol for Labour Induction at Term
A randomised control trial to compare oral and vaginal misoprostol for induction of labour in term patients.The objective is to determine whether use of standardised vaginal misoprostol regimen will result in decreased cesaerean…
- Trial name
- NCT05957666
- Testing
- Misoprostol Oral Tablet, vaginal misoprostol
- Where
- Pakistan
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Preterm Labour
Fetal Adrenal Gland Volume Estimation Compared to Cervical Length Assessment in Prediction of Preterm Birth
If the investigators could prove that three -dimensional ultrasound measurement of fetal adrenal gland volume can accurately predict the likelihood of preterm birth in patients having symptoms and signs of PTL , they would be…
- Trial name
- NCT02351336
- Testing
- Ultrasound imaging
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Wessam Magdy Abouelghar