Clinical trials: Labour
Threatened Preterm Labour
Urinary Infection in Pregnant Women with Urinary Infection
Urine analysis and culture in patients with threatened preterm labour
- Trial name
- NCT06752161
- Testing
- Urine analysis
- Where
- Egypt
- Volunteers
- 224 people
- Sponsor
- Assiut University
Obstetric Labor, Premature
Nifedipine Versus Indomethacin in the Treatment of Preterm Labour
The purpose of this study was to compare the effectiveness of nifedipine versus indomethacin as tocolytic for the treatment of preterm labour with short cervix (< 2.5cms).
- Trial name
- NCT01360034
- Testing
- Nifedipine, Indomethacin
- Where
- Panama
- Volunteers
- 216 people
- Sponsor
- Saint Thomas Hospital, Panama
Induced Deliveries
Vaginal Misodel® in Comparison With Orally Administrated Misoprostol (Cytotec®) at Induction of Labour
The study will compare orally administrated solution of Misoprostol (Cytotec®) with vaginal slow release (7ug/h) Misoprostol (Misodel®) regarding efficacy and safety during labour.
- Trial name
- NCT02918110
- Testing
- Misoprostol
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska Institutet
Pregnancy Related
DIGItal Early Labour. A Digital Application for Coping in Early Phase of Labour.
All first-time mothers in Sweden are offered parental support, but local conditions mean that not everyone gets the opportunity to take part in this.
- Trial name
- DIGI-EL (NCT05122390)
- Testing
- Contraction Coper, Contraction Coper Plus
- Where
- 2 sites in Sweden
- Volunteers
- 480 people
- Sponsor
- Värmland County Council, Sweden
Obstetric Labour, Premature
A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor
The study's primary objective is to demonstrate the superiority of retosiban to prolong pregnancy and improve neonatal outcomes compared with placebo.
- Trial name
- NEWBORN-1 (NCT02377466)
- Testing
- Retosiban IV infusion
- Where
- 50 sites in United States, Canada and 3 more
- Volunteers
- 25 people
- Sponsor
- GlaxoSmithKline
Prolonged Labor, Labor Dystocia
Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour
The goal of this clinical trial is to learn if oral bicarbonate can treat prolonged labour in nulliparous women with prolonged labour.
- Trial name
- ProLabour (NCT07321379)
- Testing
- Sodium bicarbonate
- Where
- 3 sites in Denmark
- Volunteers
- 1,520 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Post Partum Haemorrhage
Intramuscular Oxytocics: A Randomised Control Trial
A quarter of all pregnancy and child-birth related deaths are due to excessive bleeding after the birth, "post-partum haemorrhage" (PPH). In the UK, PPH affects approx 10% of new mothers.
- Trial name
- IMox (NCT02216383)
- Testing
- Carbetocin, Syntocinon, Syntometrine
- Where
- 5 sites in United Kingdom
- Volunteers
- 5,798 people, healthy volunteers welcome
- Sponsor
- North Bristol NHS Trust
Placenta Previa Bleeding
High Versus Low Dose of Magnesium Sulfate as Initial Tocolytic Agent for Preterm Labour in Symptomatic Placenta Previa.
To assess the efficacy and safety of alternative magnesium sulfate regimens when used as single agent tocolytic therapy for prevention of preterm labour in patients with symptomatic placenta previa and subsequent changes in the…
- Trial name
- NCT04599868
- Testing
- Magnesium sulfate
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Labor Analgesia
Neuroaxial Labour Analgesia
The primary outcome of this clinical trial is to compare the pain scores during labour and delivery of combined spinal epidural without intrathecal opioids and dural puncture epidural The secondary objective of this study is to…
- Trial name
- NCT03980951
- Testing
- Dural Puncture Epidural Technique, Combined Spinal Epidural without intrathecal opioids, epidural
- Where
- 2 sites in Egypt, Kuwait
- Volunteers
- 120 people
- Sponsor
- Wahba bakhet
Birth; Delayed
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour
In a randomized control trial conducted in six study centers/labour wards in Sweden, consenting nulliparous women in active phase of labour and with a defined delayed labour progress will be randomized to receive a regimen of…
- Trial name
- OxyHighLow (NCT01587625)
- Testing
- Oxytocin
- Where
- 2 sites in Sweden
- Volunteers
- 1,376 people
- Sponsor
- Göteborg University
Obstetric; Injury Pelvic Floor
The Effect of Pregnancy and Labour on the Pelvic Floor Diagnosed With 3D and 4D Ultrasound
Injuries to the pelvic floor muscles and fascias during delivery and childbirth may lead to urinary incontinence (25-45 %), faecal incontinence (11-45%), pelvic organ prolapse (7-23%), sexual dysfunction (15-33 %) and chronic…
- Trial name
- NCT01045135
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
DELAYED LABOUR
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour in Obese Women
Obesity is one of the biggest public health problems of the 21st century as it increases the risk of many co-morbid medical conditions.
- Trial name
- NCT03604874
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- Assiut University
Post Partum Haemorrhage
Improving Management of Post-partum Haemorrhage With Quantra® System
Post partum haemorrhage is a concerning situation in maternity wards, though it is not the first cause of maternal mortality anymore.
- Trial name
- Quantralab (NCT05336838)
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Premature Rupture of Membranes at Term
Comparison of Misoprostol and Prostaglandin E2 (PGE2) Gel for Induction of Labour in Premature Rupture of Membranes at Term
The purpose of this study is to determine whether induction of labor with vaginal misoprostol application will result in fewer cesarean deliveries than vaginal PGE2 gel application in women with premature rupture of membranes at…
- Trial name
- NCT00355303
- Testing
- Misoprostol, PGE2 gel
- Where
- India
- Volunteers
- 932 people
- Sponsor
- Nilratan Sircar Medical College
Preterm Labour
Fetal Adrenal Gland Volume Estimation Compared to Cervical Length Assessment in Prediction of Preterm Birth
If the investigators could prove that three -dimensional ultrasound measurement of fetal adrenal gland volume can accurately predict the likelihood of preterm birth in patients having symptoms and signs of PTL , they would be…
- Trial name
- NCT02351336
- Testing
- Ultrasound imaging
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Wessam Magdy Abouelghar
Labor Pain, Virtual Reality
Virtual Reality, Experience During Labour; a Qualitative Research (VIREL)
Childbirth is associated with labour pain and can be regarded as one of the most serious kinds of pain. Labour pain management methods include pharmacological and non-pharmacological methods.
- Conditions
- Labor Pain, Virtual Reality, Analgesia, Pain
- Trial name
- VIREL (NCT04858984)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
Labor Pain
Does Ultrasound Scanning of the Lumbar Spine Improve Patient Satisfaction and the Ease of Insertion Epidurals?
Ultrasound scanning of the back has been shown to increase success when used to guide epidural catheter insertion. However, this technique is not applied widely in clinical practice.
- Trial name
- NCT00996905
- Testing
- Portable ultrasound machine
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Postpartum Haemorrhage
Carbetocin Versus Syntometrine for the Third Stage of Labour
Intramuscular carbetocin is as effective as intramuscular syntometrine for the prevention of postpartum haemorrhage
- Trial name
- NCT00499005
- Testing
- Syntommetrine and Carbetocin
- Where
- Singapore
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Gestational Diabetes Mellitus (GDM)
The Feasibility Of Expectant Management Versus Induction At 38 Weeks Among Individuals With Gestational Diabetes Mellitus: A Randomized Controlled Pilot Trial (EAGER Pilot Trial)
The EAGER pilot trial is designed to assess the feasibility of a Canadian, multicentre prospective randomized open-label blinded end-point (PROBE) clinical trial addressing whether induction of labour (IOL) at 38 weeks' gestation…
- Trial name
- EAGER Pilot (NCT06641141)
- Testing
- Induction of Labour
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- Ottawa Hospital Research Institute
Induced; Birth, Cervical Dilatation
Induction to Labour With Double Cervical Ballon at Home Versus at Hospital
The goal of this clinical trial] is to compare the outcomes between induction to labour at home versus hospitalized. The main questions it aims to answer are: Can the induction to labour at home with cervical rippening ballon…
- Conditions
- Induced; Birth, Cervical Dilatation, Live Birth
- Trial name
- INDOBAMHOS (NCT06053073)
- Testing
- Cervical rippening at home, Cervical rippening in the hospital
- Where
- Spain
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau