Clinical trials: Labour
Induction of Labour
To Study the Efficacy and Safety of Misoprostol by Sublingual Routes for Induction of Labour
This research is to compare the efficacy and the safety of sublingual misoprostol with vaginal misoprostol administration for the induction of labour for primigravida at 41 or more weeks of pregnancy.
- Trial name
- SL-IOL (NCT04887493)
- Testing
- Misoprostol
- Where
- Bhutan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Cervical Length, Preterm Birth
Development of a Screening Tool By Utilising Cervical Length Measurement In Relation To Body Mass Index (BMI) For Early Identification And Intervention Of Preterm Birth
This is a prospective study where pregnant women between 16-24 weeks gestation attending the Antenatal Clinic, Fetomaternal clinic or Obstetrics \& Gynaecology Admission Centre (OGAC) at Hospital Serdang or Hospital Pengajar UPM…
- Trial name
- NCT04922671
- Where
- 2 sites in Malaysia
- Volunteers
- 145 people
- Sponsor
- Universiti Putra Malaysia
Premature Labour
Vaginal Progesterone for Prevention of Preterm Labor in Asymptomatic Twin Pregnancies With Sonographic Short Cervix
To evaluate the value of vaginal progesterone therapy for reduction of preterm labor in asymptomatic twin pregnancies who have sonographic short cervix
- Trial name
- NCT02338830
- Testing
- Progesterone
- Where
- 2 sites in Egypt
- Volunteers
- 182 people
- Sponsor
- Mohamed Sayed Abdelhafez
Labor Pain
A Novel Approach to Optimize Programmed Intermittent Epidural Bolus (PIEB) Delivery for Labour Analgesia
Programmed intermittent epidural bolus (PIEB) for labour analgesia allows an epidural pump to be programmed to deliver small amounts of the local anesthetic and opioid solution at regularly timed intervals.
- Trial name
- NCT03871530
- Testing
- Coordinate A, Coordinate B, Coordinate C
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- IWK Health Centre
Anesthesia, Epidural, Opioid
Effect of Epidural Opioid Administered in the First A Period on the Progress of Labour
Epidural anesthesia is used to relieve labour pain which helps reduce labour stress, increase comfort and improve cooperation with medical personnel.
- Conditions
- Anesthesia, Epidural, Opioid, Labor Pain
- Trial name
- NCT03344042
- Testing
- Fentanyl, Sufentanil
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Warsaw
Labour Pain
Acupuncture With Manual and Electrical Stimulation to Reduce Labour Pain
The purpose of this study is to evaluate the effect of manual acupuncture and electro-acupuncture on labour pain.
- Trial name
- NCT01197950
- Testing
- Manual Acupuncture, Electro Acupuncture
- Where
- Sweden
- Volunteers
- 303 people
- Sponsor
- University of Skövde
18 Years and Older, Term Pregnancy
The Effect of the World Health Organisation-Based Intrapartum Care Model on Labour Pain, Comfort, Satisfaction and Postpartum Depression
This randomized controlled trial aims to evaluate the effects of the World Health Organization-based intrapartum care model on labour pain, labour comfort, childbirth satisfaction, and postpartum depression.
- Trial name
- WHO-ICARE Tria (NCT07451691)
- Testing
- WHO-ICARE Trial
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Induction of Labor Affected Fetus / Newborn
An RCT of a Synthetic Osmotic Cervical Dilator for Induction of Labour in Comparison to Dinoprostone Vaginal insErt
Induction of labour (where labour is started artificially) is traditionally carried out with a range of different drugs or by surgery (rupturing the membranes or 'waters').
- Trial name
- SOLVE (NCT03001661)
- Testing
- Dilapan-S, Dinoprostone
- Where
- United Kingdom
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Pain Relief in Labour
A Randomised Controlled Trial of Remifentanil Intravenous Patient Controlled Analgesia (PCA) Versus Intramuscular Pethidine for Pain Relief in Labour
Childbirth can be an extremely painful and the provision of pain relief during labour is a vital component of a positive maternal experience.
- Trial name
- RESPITE (NCT02179294)
- Testing
- Pethidine, Remifentanil
- Where
- United Kingdom
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Previable Labour With Intact Membranes
A Combination of Antibiotics to Decrease Neonatal Morbidity and Mortality for Previable Threatened Labor
The purpose of this study is to determine whether a combination of antibiotics (cephalosporin 3rd generation, clarithromycin, metronidazole) are effective to prolong pregnancies complicated with previable threatened labour with…
- Trial name
- ECHEC-MAT (NCT06572761)
- Testing
- Combination of antibiotics, Emergency cerclage, Vaginal progesterone
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy, Labour
Confident Birthing: What Influences Women's Confidence for Birth?
This is a grounded theory study aiming to understand women's perception of what influences their confidence for birth during labour and birth. Data is being collected using interviews and social media sources.
- Conditions
- Pregnancy, Labour, Birth, Psychosocial Wellbeing
- Trial name
- NCT03141320
- Testing
- Interview/observation of social media comments
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Cervix; Pregnancy
Comparative Study Between Only Vaginal Misoprostol and Vaginal Misoprostol and Estradiol Cream
To compare the safety and effectiveness of vaginal misoprostol with combined vaginal misoprostol and estradiol for induction of labour in unfavorable cervix
- Trial name
- NCT05306405
- Testing
- Vaginal Tablet
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vaginal Delivery
Effect of Intravenous Hyoscine Butylbromide Injection on First Stage Labour in Primigavidae
A case control study conducted on 120 women coming to Cairo University Maternity Hospital .Patients who meet the inclusion criteria were asked to participate in the study and a verbal consent was obtained from each patient.
- Trial name
- NCT02824679
- Testing
- hyoscine butylbromide, saline
- Volunteers
- 200 people
- Sponsor
- Ahmed M Maged, MD
Oxygen Inhalation Therapy, Labour
Maternal Oxygen Administration for Fetal Distress II
Supplementary oxygen is routinely administered to patients, even those with adequate oxygen saturations, in the belief that it increases oxygen delivery.
- Conditions
- Oxygen Inhalation Therapy, Labour, Fetal Distress
- Trial name
- NCT03764696
- Testing
- tight-fitting simple facemask
- Where
- 3 sites in China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Navy General Hospital, Beijing
Labor and Delivery
Role of the WHO Labour Care Guide in Improving Maternal and Fetal Outcomes
The goal of this randomized controlled trial is to compare the effectiveness of WHO labour care guide (LCG) with the WHO modified partogragh in improving the maternal and fetal outcomes among primigravida and multigravida in…
- Trial name
- NCT07445373
- Testing
- Group A (Intervention Arm): Monitoring with WHO Labour Care Guide), Group B (Control Arm): Monitoring with Standard WHO Partograph)
- Where
- Pakistan
- Volunteers
- 114 people
- Sponsor
- Khyber Teaching Hospital
Well-Being, Psychological
The Patient AS EDUcator in Anesthesia: Exploring the Patients' and Providers' Experience During Neuraxial Labour Analgesia
During the process of labour and delivery, patients may experience a wide range of events in a short time frame. This study focuses on exploring these experiences and aims to incorporate the improvements from these experiences so…
- Trial name
- PAS-EDU-NLA (NCT06368583)
- Testing
- Interview
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Labor Pain
The Effect of Oxycodone to the Placental Circulation at Early Labour
Oxycodone is used to treat pain in early labor, however the effect of oxycodone to placental or fetal circulation has not been evaluated. Oxycodone is increasingly used to treat labor pain in the early phase.
- Trial name
- oksisynnII (NCT02573831)
- Testing
- Oxycodone
- Where
- Finland
- Volunteers
- 22 people
- Sponsor
- Kuopio University Hospital
Labor Pain
Prostin and Propess in Induction of Labor
The purpose of the study was to compare the safety and efficacy of two agents used in induction of labor Propess (Controlled release dinoprostone, PGE2, pessary) and Prostin E2 (Dinoprostone vaginal Tablet).
- Trial name
- NCT01635439
- Testing
- Propess, Prostin E2
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Induction of Labour With Misoprostol
Comparison of Oral Versus Vaginal Misoprostol for Labour Induction at Term
A randomised control trial to compare oral and vaginal misoprostol for induction of labour in term patients.The objective is to determine whether use of standardised vaginal misoprostol regimen will result in decreased cesaerean…
- Trial name
- NCT05957666
- Testing
- Misoprostol Oral Tablet, vaginal misoprostol
- Where
- Pakistan
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Labor Pain
Usefulness of the Tsui Test in Combined Spinal-Epidural Analgesia in Labour
Combined spinal epidural anesthesia (CSE) is a very effective technique to provide labor analgesia. One of the disadvantages of this technique is the delay in recognizing an error in the position of the epidural catheter because…
- Trial name
- NCT00464841
- Testing
- Combined spinal epidural, Tsui Test for intrathecal catheter
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital