Clinical trials: Labour
Normal Labour
Evaluation of Management and Outcomes of Normal Labor in Eldakhla Hospital
Labour is a physiologic process during which the products of conception are expelled outside of the uterus. Labour is achieved with changes in the biochemical connective tissue and with gradual effacement and dilatation of the…
- Trial name
- NCT06922435
- Volunteers
- 176 people
- Sponsor
- Assiut University
Labor Pain
Programmed Intermittent Epidural Bolus For Laboring Obstetrical Women
Comparison of three programmed intermittent epidural bolus (PIEB) pump settings for maintenance of labour analgesia.
- Trial name
- NCT03712735
- Testing
- Bupivacaine 0.08% - fentanyl 2mcg
- Where
- Canada
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Labour Analgesia, Epidural Anaesthesia, Duration of Labour
Impact of Timing of Neuraxial Analgesia on Obstetric, Anesthesiologic and Neonatal Outcomes in Induced Labour
The aim of this observational study is to assess the effect of early labour analgesia on obstetric and neonatal outcomes in induced labour in primiparous women with a full-term pregnancy whose labour was induced with a Cook…
- Conditions
- Labour Analgesia, Epidural Anaesthesia, Duration of Labour, Labor, Induced
- Trial name
- TAIL (NCT06886555)
- Testing
- Epidural analgesia for labour pain
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Labor Complication
A-BIRTHPERFORM Versus Conventional Partogram in the Improvement of Birth Results
Midwives and Obstetricians when assisting women during labour do not follow the clinical guidelines on labour process care,in many cases oxytocin is used routinely without medical indication, and ends in the erroneous use of…
- Trial name
- A-BRTHPRFORM (NCT04009993)
- Testing
- A-BIRTHPERFORM digital tool
- Volunteers
- 969 people, healthy volunteers welcome
- Sponsor
- Hospital del Mar
Labor Fast
Isosorbide Mononitrate in Induction of Labour
Induction of labor is defined as the process of artificially initiating uterine contractions, prior to their spontaneous onset, with progressive effacement and dilatation of the cervix and ultimately, the delivery of the baby.
- Trial name
- NCT04482881
- Testing
- Isosorbide Mononitrate 40 MG, Isosorbide Mononitrate 60 MG, Misoprostol
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Labor
Effect of Fluid Oral Intake During Labour
Fasting during labour is a usual conduct in many hospitals around the world (due to the theorical risk of bronchoaspiration). There is little evidence supporting this conclusion.
- Trial name
- NCT01349686
- Testing
- Diet, Fasting
- Where
- Panama
- Volunteers
- 348 people
- Sponsor
- Saint Thomas Hospital, Panama
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Post-Dural Puncture Headache, Chronic Headache
Long-term Complications of Unintentional Dural Puncture During Labour Epidurals and Epidural Blood Patch.
The investigators plan to evaluate long-term consequences of unintentional dural puncture in women who had this complication during labor epidural insertion at Mount Sinai Hospital.
- Trial name
- NCT04696627
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Gestational Diabetes Mellitus
Insulin Dependent Gestational Diabetes Mellitus: Randomized Trial of Induction of Labour at 38 and 40 Weeks of Gestation
To evaluate the impact of induction of labour at 38 weeks with the induction of labour at 40 weeks in women with insulin dependent gestational diabetes mellitus on maternal and fetal outcome.
- Trial name
- NCT01256892
- Testing
- induction of labour
- Sponsor
- Medical University of Vienna
Postpartum Hemorrhage
In Vitro Optimization of Oxytocin-induced Myometrial Contractility by Propranolol
The rates of cesarean deliveries (CD) and postpartum hemorrhage (PPH) are on the rise, with failed induction and augmentation of labor as major contributing factors.
- Trial name
- NCT03434444
- Testing
- Oxytocin, Propranolol
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Epidural Analgesia, Epidural Analgesia for Labour and Delivery
EpiFaith Resident Learning Curve Trial
This study aims to evaluate the impact of the EpiFaith® syringe on the learning curve of anesthesia residents for the labor epidural technique.
- Conditions
- Epidural Analgesia, Epidural Analgesia for Labour and Delivery, Learning Curve
- Trial name
- NCT07395622
- Testing
- EpiFaith epidural syringe, Control (glass) syringe
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pain, Pain Threshold
Role of B2 Adrenergic Receptors in Labor Pain
The study aims to understand why labor is more painful for some women compared to others. The study will study whether a woman's baseline pain sensitivity, beta2 adrenergic receptor genotype is related to her pain in labor for…
- Conditions
- Pain, Pain Threshold, Labour Pain
- Trial name
- NCT00385294
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Labour, Induced
Comparative Bioavailability Study of Two Misoprostol Formulations
The purpose of this study is to compare pharmacokinetics of two formulations of misoprostol following single dose administration in adult women being given misoprostol for cervical ripening and induction of labour.
- Trial name
- NCT02516631
- Testing
- Angusta™, Cytotec®
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Region Skane
Premature Rupture of Membranes at Term, Induction of Labour
Propess Versus Prostin for Induction of Labour in Women With Term PROM
Premature rupture of membranes (PROM) at term is a rupture that occurs at term (> 37 weeks) before the start of labor. The purpose of the study was to compare the safety and efficacy of two agents used in induction of labor in…
- Trial name
- PESTIBOR (NCT04743297)
- Testing
- Prostaglandin E2 (Propess), Prostaglandin E2 (Prostin)
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Hand Grasp
Hand Grip Strength in Chilean Adults
Context Hand grip strength (HGS) is an important parameter to assess hand function during the rehabilitation of hand injuries. HGS serves as a clinical predictor of complications after surgery.
- Trial name
- NCT05396365
- Testing
- Dynamometry
- Where
- Chile
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Maria Jesus Mena-Iturriaga
Preterm Birth
Prediction of Preterm Delivery by Serum Ischemia Modified Albumin, Biglycan and Decorin Levels in Women With Threatened Preterm Labour
In this study, the levels of ischemia modified albumin, biglycan and decorin in the serums of pregnant women hospitalized for preterm labor will be examined.
- Trial name
- NCT04451928
- Testing
- Serum sample analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ismail Biyik
Labour Analgesia and Neonate Activity
Labour Analgesia and Movement in Babies
This study aims to measure movements in babies after they are born using an actigraph, a wristwatch-sized device worn on the ankle, which works similarly to the device used by runners to count the number of steps they have taken.
- Trial name
- LAMB (NCT01280084)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Prevention, Newborn Complication
The Effects Of Pushing Techniques During Second Stage Of Labour On Maternal and Newborn Health
Purpose :To determine the impact of directed Valsalva's's versus spontaneous pushing techniques during second stage of labour on postpartum maternal fatigue. .
- Trial name
- NCT04207658
- Testing
- Valsalva's Style Pushing
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pain
A Randomized Control Trial on Intravenous Paracetamol Versus Intramuscular Tramadol as Intra Partum Labor Analgesia
ABSTRACT BACKGROUND: Labor pain is one of the most excruciating pain experienced by women. It affects maternal psychology and the course of labor causing apprehension, anxiety, and stress.
- Trial name
- NCT06371144
- Testing
- Paracetamol
- Where
- Nigeria
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Labour Analgesia
A Digital Educational Resource to Improve Preparedness for Shared Decision Making About Labour Analgesia
Labour analgesia decisions are often made under time pressure, while in pain, which may lead patients to feel unprepared or uninformed.
- Trial name
- PrepDM (NCT07516171)
- Testing
- Preparation for Decision Making (PrepDM) Scale, Questionnaire
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital