Clinical trials: Labour
Pregnancy Related
DIGItal Early Labour. A Digital Application for Coping in Early Phase of Labour.
All first-time mothers in Sweden are offered parental support, but local conditions mean that not everyone gets the opportunity to take part in this.
- Trial name
- DIGI-EL (NCT05122390)
- Testing
- Contraction Coper, Contraction Coper Plus
- Where
- 2 sites in Sweden
- Volunteers
- 480 people
- Sponsor
- Värmland County Council, Sweden
Postpartum Bleeding
Postpartum Uterotonic Administration
The investigators are planning to determine the effect of the timing of oxytocin administration on the amount of blood loss, necessity for additional medical or surgical interventions.
- Trial name
- NCT02495272
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Urinary Tract Infection in Pregnancy, Urinary Tract Infection Following Delivery
Postnatal Prevalence of Bacteriuria in Women With Catheter Versus no Catheter in Labour
Catheterisation is an accepted tool in intrapartum bladder care and indwelling catheters are used routinely before elective caesarean sections.
- Conditions
- Urinary Tract Infection in Pregnancy, Urinary Tract Infection Following Delivery, Catheter Infection
- Trial name
- NCT03914144
- Testing
- Catheter insertion
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Obstetric Labour, Premature, Premature Ejaculation
A First Time in Human Study in Healthy Male Volunteers for Compound GSK557296.
A study conducted on healthy volunteers to determine the safety, tolerability and affect on the human body by experimental drug GSK557296.
- Trial name
- NCT00549211
- Testing
- GSK557296
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Vaginal Delivery
Audit of Management of First Stage of Labour in Assiut University Hospitals : a Quality Improvement Project
auditing the current management of first stage of normal vaginal deliveries at Assiut university hospitals emergency obstetric care
- Trial name
- NCT05143944
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Induced; Birth, Delivery Complication
The Norwegian Induction Project: a Pilot for a Prospective National Audit
The worldwide rate of induction of labour has been steadily increasing over the last 15 years, a trend that is reflected in Norway.
- Conditions
- Induced; Birth, Delivery Complication, Indications for Care in Pregnancy; Labor; and Delivery
- Trial name
- NCT03730220
- Where
- Norway
- Volunteers
- 1,846 people
- Sponsor
- Oslo University Hospital
DELAYED LABOUR
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour in Obese Women
Obesity is one of the biggest public health problems of the 21st century as it increases the risk of many co-morbid medical conditions.
- Trial name
- NCT03604874
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- Assiut University
Labor Pain
Intranasal Fentanyl in Treatment of Labour Pain
Physiological changes during pregnancy are known to affect the pharmacokinetics of many drugs. Intranasal fentanyl is an interesting option for obstetric analgesia, but its use in pregnant patients has not been established.
- Trial name
- fentaobs (NCT02571179)
- Testing
- intranasal fentanyl 50 microg dose up to 250 microg
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Kuopio University Hospital
Prelabor Rupture of Membranes
Dinoprostone Induction vs. Expectant Management After PROM at Term
Prelabour rupture of membranes (PROM) is associated with intrauterine infection and maternal and neonatal consequences. This risk increases with the length of time from PROM to delivery.
- Trial name
- NCT05430711
- Testing
- Dinoprostone
- Volunteers
- 70 people
- Sponsor
- University Medical Centre Ljubljana
Pregnancy, Covid19
Prevalence of COVID-19 (Coronavirus Disease 19) in Pregnant Women on Labor in a Public Hospital in Chile (COroNavirus diSease Covid-19 pandEmic iN ChilE)
This study aim is to assess the prevalence of SARS-COV-2 in unselected pregnant women on labour (or a predictable delivery during next 24 hours), their outcome and sociodemographic conditions.
- Conditions
- Pregnancy, Covid19, Labor (Obstetrics)--Complications, Demography
- Trial name
- CONSCIENCE (NCT04551690)
- Where
- Chile
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios, Santiago
Cesarean Delivery, Cervical Ripening
Latent Phase Membrane Stripping for Caesarean Section Reduction
In the Hospital Escuela, the availability of beds and criteria for admission to the intensive care unit ICU are not the same, the use of this marker is questionable, as it is affected by the level of complexity of care provided…
- Conditions
- Cesarean Delivery, Cervical Ripening, Latent Phase Labour
- Trial name
- DEMEM (NCT06809985)
- Testing
- Hamilton maneuver
- Where
- Honduras
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Pregnancy Complications
Effects of Regular Exercise During Pregnancy
There is a great lack of results from randomized clinical trials with high methodological quality, assessing the effects of exercise during pregnancy.
- Trial name
- NCT00476567
- Testing
- standard, specific training program
- Where
- Norway
- Volunteers
- 855 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Postpartum Hemorrhage
Comparison of Inhaled Oxytocin (IH) With Intramuscular (IM) Oxytocin in Pregnant Women and With Intravenous (IV) Oxytocin in Healthy Non-pregnant Women
The study will evaluate a stable, dry-powder formulation of oxytocin, with the goal of reducing post-partum hemorrhage morbidity and mortality in resource poor settings.
- Trial name
- NCT02999100
- Testing
- IH Oxytocin, IM Oxytocin, IV Oxytocin
- Where
- 3 sites in Australia, United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Labor Induction
Observatory on Artificial Labour-induction Methods and Measuring Immediate Postpartum Maternal Satisfaction
Our hypothesis is that there is one sequence of labour-induction that leads to a better experience of childbirth than others. This is based on the following underlying theories : Maternal satisfaction depends on the number of…
- Trial name
- SATISFACC (NCT04075630)
- Where
- 2 sites in France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Induction of Labour
Women's Knowledge About Induction of Labour and Its Association With Their Experience
Induction of labour (IOL) is a common procedure to initiate childbirth, around one in three pregnant women having their labour induced in the UK.
- Trial name
- INFORM (NCT07616765)
- Testing
- Survey and Interview-Based Assessment
- Volunteers
- 112 people
- Sponsor
- Imperial College London
Placental Bleeding
Placental Drainage Versus no Placental Drainage After Vaginal Delivery in the Management of Third Stage of Labour
In this randomized controlled study, 222 pregnant women who admitted to Zeynep Kamil Women and Children's Health Training and Research Hospital from December 2016 and July 2017 were included.
- Trial name
- NCT03542292
- Testing
- placental drainage
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Obstetric Labour, Premature
Study to Investigate the Pharmacokinetics (PK), Safety and Tolerability of Retosiban in Healthy Japanese Women
This study in healthy, adult Japanese women will characterize the PK, safety and tolerability of retosiban at the therapeutic doses planned to be evaluated in Phase 3.
- Trial name
- NCT02377414
- Testing
- Retosiban solution for Infusion
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cervical Dilatation, Bishop Score
the Effects of Epidural Fentanyl on Vaginal Delivery
The study hypothesis was that epidural fentanyl may accelerate the dilation of the cervix and possibly result in a shorter duration of vaginal delivery.
- Conditions
- Cervical Dilatation, Bishop Score, Duration of Delivery
- Trial name
- EFVD (NCT02135224)
- Testing
- Fentanyl, Normal saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Athens
Labor Complication
Traditional WHO Partograph and Korle-Bu Modified WHO Partograph for Uncomplicated Labour
Brief Background: The partograph is a graphical representation of the events in the first stage of labour. It is an instrument used in monitoring the well being of both the pregnant woman and her fetus (es) as they go through the…
- Trial name
- NCT05837559
- Testing
- Korle-Bu Modified WHO Partograph for Uncomplicated Labour
- Where
- Ghana
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Epidural Analgesia for Labour and Delivery
Cross-legged Versus Traditional Sitting Position for the Success of Epidural Analgesia During Labor
The success of an epidural analgesia catheter placement depends on the parturient position. A poor posture can increase the number of punctures, patient discomfort, and risk of complications.
- Trial name
- IP3 (NCT04754282)
- Testing
- Position of labouring women for epidural analgesia catheter placement : Traditional Sitting Position (TSP), Position of labouring women for epidural analgesia catheter placement : Cross-legged Sitting Position (CSP)
- Where
- France
- Volunteers
- 457 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris