Clinical trials: Labour
Labour Duration and Metoclopramide
Metoclopramide and the Length of First Stage of Labor , a Randomized Controlled Trial
Reducing the length of labor is a highly desirable goal of intrapartum care, both from a perspective of maternal and fetal well-being and for the providers of the birth services.
- Trial name
- NCT04969120
- Testing
- Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labour
Role of Simulators in Improving Obstetric Vaginal Examination Skills
A prospective study will be performed at the Department of Obstetrics and Gynecology at (VESSALKA unit),at El kasr Al_Ainy hospital, cairo university.
- Trial name
- NCT05190692
- Testing
- Use simulators in Obstetrics vaginal examination
- Where
- 3 sites in Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Labour;Obstructed, Labor Dystocia
Propranolol for Protracted Labor
Induction of labor is one of the most common procedures performed on labor and delivery. In the United States, more than 20 percent of pregnant women undergo an induction of labor [1].
- Trial name
- PRO-Labor (NCT04741698)
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Labour Pain
Development of a Multi-attribute Health Index: to Measure the Quality of Labour Analgesia: The QLA Index
The findings of this research will be used to develop a scale for measuring the quality of epidural pain relief achieved during labour and vaginal delivery.
- Trial name
- NCT01177046
- Where
- Canada
- Volunteers
- 752 people
- Sponsor
- Sunnybrook Health Sciences Centre
DELAYED LABOUR
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour in Obese Women
Obesity is one of the biggest public health problems of the 21st century as it increases the risk of many co-morbid medical conditions.
- Trial name
- NCT03604874
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- Assiut University
Duration of Labour
Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour
BACKGROUND Prolonged labour can lead to increased maternal and neonatal mortality and morbidity. The risk for complications of prolonged labour is more in poor resource settings.
- Trial name
- NCT05222646
- Testing
- Metoclopramide
- Where
- Nigeria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uwakwe Emmanuel Chijioke
Induction of Labour
Double Foley Catheter For Cervical Ripening
To compare the efficacy of three mechanical devices for pre-induction of labour cervical ripening: the Single Foley Catheter, Double Foley Catheter (a new handmade device) and Cook cervical ripening balloon.
- Trial name
- NCT04454346
- Testing
- Double Foley Catheter For Ripening The Unfavorable Cervix
- Where
- Turkey (Türkiye)
- Volunteers
- 222 people
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Patients With a Risk of Preterm Labour
Advantage of Detection of phIGFBP-1 to Reduce Hospitalization Time for Stable Patients With a Risk of Preterm Labour.
It consists of evaluating the advantage of routine detection of phIGFBP-1 to reduce the total duration of hospitalization for patients with a risk of preterm labor before 32 weeks of gestation without increasing the number of…
- Trial name
- NCT01987024
- Testing
- Actim Partus® test, usual procedure
- Where
- France
- Volunteers
- 272 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Induction of Labour
To Study the Efficacy and Safety of Misoprostol by Sublingual Routes for Induction of Labour
This research is to compare the efficacy and the safety of sublingual misoprostol with vaginal misoprostol administration for the induction of labour for primigravida at 41 or more weeks of pregnancy.
- Trial name
- SL-IOL (NCT04887493)
- Testing
- Misoprostol
- Where
- Bhutan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Obstetric Labor Complications, Vacuum Extraction; Failure, Affecting Fetus or Newborn
Comparison of Prevention and Appropiate Obstetric Interventions for Prolonged Second Stage Labor at Term Pregnancies During Vaginal Delivery
Randomized Control Trial for Comparison of Prevention and Appropiate Obstetric Interventions for Prolonged Second Stage Labor at Term Pregnancies During Vaginal Delivery.
- Conditions
- Obstetric Labor Complications, Vacuum Extraction; Failure, Affecting Fetus or Newborn, Complicated Labour/Delivery Livebirth
- Trial name
- NCT04888871
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Anxiety, Hormone, Labour, Pain, Midwife, Pregnant, Transcutaneous Electrical Nerve Stimulation
Evaluation of the Effect of Transcutaneous Electrical Nerve Stimulation During Delivery
Pain and anxiety levels experienced during labour are important factors affecting mother and baby health. An indicator that affects these factors is the levels of hormones that special for birth in the mother's blood.
- Trial name
- NCT04851938
- Testing
- transcutaneous electrical nerve stimulation device
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Complication of Anaesthesia During Labour and Delivery
Plethysmographic Variability Index in Post Spinal Anesthesia Hypotension in Cesarean Section
Full term pregnant female patients presented for elective C.S for single viable fetus will be included in this study. Before anesthesia, the patient will be attached to a monitor of: ECG , heart rate, non invasive blood pressure…
- Trial name
- NCT04010318
- Testing
- Spinal Anesthesia
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Premature Rupture of Membranes at Term, Induction of Labour
Propess Versus Prostin for Induction of Labour in Women With Term PROM
Premature rupture of membranes (PROM) at term is a rupture that occurs at term (> 37 weeks) before the start of labor. The purpose of the study was to compare the safety and efficacy of two agents used in induction of labor in…
- Trial name
- PESTIBOR (NCT04743297)
- Testing
- Prostaglandin E2 (Propess), Prostaglandin E2 (Prostin)
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Term Labour
Accuracy and Reliability of Novii: Fetal Heart Rate (FHR), Maternal Heart Rate (MHR) and Uterine Contraction (UA) Compared With Doppler, Scalp Fetal Scalp Electrode (FSE), Tocodynamometer (TOCO) and Intra Uterine Pressure Catheter (IUPC)
Accuracy and Reliability of the Novii device (fetal heart rate, maternal heart rate and uterine activity) compared with Food and Drug Administration (FDA) approved techniques
- Trial name
- NCT03409146
- Testing
- Monica Novii Wireless Patch System
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Obstetric Labour, Premature
A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour
The primary objective of this study is to demonstrate the superiority of retosiban to prolong pregnancy in females with spontaneous preterm labor compared with atosiban.
- Trial name
- NCT02292771
- Testing
- Retosiban, Atosiban
- Where
- 21 sites in Belgium, Germany and 7 more
- Volunteers
- 97 people
- Sponsor
- GlaxoSmithKline
Obstetric Labour, Premature
A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor
The study's primary objective is to demonstrate the superiority of retosiban to prolong pregnancy and improve neonatal outcomes compared with placebo.
- Trial name
- NEWBORN-1 (NCT02377466)
- Testing
- Retosiban IV infusion
- Where
- 50 sites in United States, Canada and 3 more
- Volunteers
- 25 people
- Sponsor
- GlaxoSmithKline
Induction of Labour
Transvaginal Ultrasound As Predictors of Successful Induction of Labour
To compare the use of transvaginal ultrasound (TVUS) of cervix to the Bishops score prior to induction of labour in term pregnancies, and the ability to predict Caesarean delivery for failure to progress.
- Trial name
- NCT04477226
- Testing
- Transvaginal ultrasound scan
- Where
- Malaysia
- Volunteers
- 294 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Obstetric Labour, Premature
Follow up Study to Assess Long Term Safety and Outcomes in Infants and Children Born to Mothers Participating in Retosiban Treatment Studies
The primary objective of this study is to assess the safety and outcomes of infants and children who were exposed to retosiban or comparator in utero in the Phase III spontaneous preterm labor (SPTL) treatment studies, to provide…
- Trial name
- ARIOS (NCT02292784)
- Testing
- Retosiban, Atosiban
- Where
- 26 sites in United States, Belgium and 9 more
- Volunteers
- 98 people
- Sponsor
- GlaxoSmithKline
Oxygen Inhalation Therapy, Second Stage of Labour
Maternal Oxygen Administration for Fetal Distress
Supplementary oxygen is routinely administered to patients, even those with adequate oxygen saturations, in the belief that it increases oxygen delivery.
- Conditions
- Oxygen Inhalation Therapy, Second Stage of Labour, Fetal Distress
- Trial name
- NCT02221440
- Testing
- Low flow nasal oxygen, Low flow room air
- Where
- 3 sites in China
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Navy General Hospital, Beijing