Clinical trials: Labour Induction
Labor Onset and Length Abnormalities
Effect of Tafoxiparin on Cervical Ripening and Induction of Labor in Term Pregnant Women With an Unripe Cervix
The study is designed as a randomized, Double-Blind, Placebo-Controlled, Parallel-Group Proof of Concept Study (section A) with a conditional dose finding follow up (Section B) to Evaluate the Efficacy on Cervical ripening…
- Trial name
- NCT04000438
- Testing
- DF01, PL1
- Where
- 7 sites in Finland, Sweden
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Dilafor AB
Labor; Forced or Induced, Affecting Fetus or Newborn
Foley With Oxytocin Versus Foley no Oxytocin for Induction of Labor
The overall purpose of this study is to determine if adding oxytocin to a Foley catheter for induction of labor will increase the rate of delivery within 24 hours stratified by parity.
- Trial name
- NOFOX (NCT02273115)
- Testing
- Oxytocin, Transcervical Foley catheter
- Where
- 2 sites in United States
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Induction of Labor Affected Fetus / Newborn
A Trial of Cervidil for Outpatient Pre-induction of Cervical Ripening
Induction of labor is a frequently planned obstetric procedure. Induction for women with an unfavorable cervix (bishop score <6) increases the risk of cesarean section.
- Trial name
- NCT03806231
- Testing
- Outpatient Dinoprostone 10mg, Inpatient Dinoprostone 10 mg
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Labor Pain
Prostin and Propess in Induction of Labor
The purpose of the study was to compare the safety and efficacy of two agents used in induction of labor Propess (Controlled release dinoprostone, PGE2, pessary) and Prostin E2 (Dinoprostone vaginal Tablet).
- Trial name
- NCT01635439
- Testing
- Propess, Prostin E2
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Labor Long
Low-Dose Versus High-Dose Oxytocin Dosing for Induction and Augmentation of Labor
The goal of this clinical trial is to compare oxytocin infusion rates for induction and augmentation of labor in nulliparous women.
- Trial name
- NCT05782816
- Testing
- Oxytocin (Low dose), Oxytocin (High dose)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Cervical Ripening, Induction of Labor
Foley Bulb Traction for Cervical Ripening
This study aims to determine what type of traction, weighted bag or inner thigh taping, on foley catheters for cervical ripening results in a greater cervical dilation and shorter length of labor.
- Trial name
- NCT00976703
- Testing
- weighted bag, leg taping
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Induction of Labor
Cervical Ripening for Induction of Labor: Misoprostol Versus Oxytocin in Conjunction With Foley Balloon
The purpose of this study is to specifically investigate the efficacy of an alternative pharmacologic cervical ripening agent, misoprostol, versus the standard oxytocin, as an adjunct to Foley balloon for induction of the…
- Trial name
- NCT01139801
- Testing
- Oxytocin, Misoprostol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Aultman Health Foundation
Cervical Ripening, Induction of Labor
Study of the Effectiveness of Cervical Ripening Balloon With and Without Oxytocin
Study Purpose: The purpose of this study is to determine the optimal method for induction of labor in multiparous women who present with an unfavorable cervix.
- Conditions
- Cervical Ripening, Induction of Labor, Multiparity
- Trial name
- NCT03138252
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Labor Induction, Cesarean Delivery
Induction of Labor With Oxytocin: When Should Oxytocin be Held?
The investigators propose to perform a prospective randomized control trial to compare the rate of cesarean delivery in women where Oxytocin (OT) is discontinued once active labor begins (5 cm dilation) when compared with women…
- Trial name
- NCT00957593
- Testing
- Oxytocin, Oxytocin discontinuation
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Lehigh Valley Hospital
Cervical Ripening, Labor, Induced
Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor
The purpose of this study is to determine whether the misoprostol vaginal insert (50 mcg and 100 mcg) can safely and effectively speed time to vaginal delivery compared to Cervidil (R) in women who need to have cervical ripneing…
- Trial name
- NCT00308711
- Testing
- Misoprostol vaginal insert 100 mcg, Misoprostol vaginal insert 50 mcg, Dinoprostone vaginal insert (Cervidil)
- Where
- 52 sites in United States, Canada
- Volunteers
- 1,308 people
- Sponsor
- Ferring Pharmaceuticals
Fetal Membranes, Premature Rupture, Labor, Induced/IS
Foley Catheter for Labor Induction in Women With Term and Near Term Membrane Rupture
In women undergoing labor induction for membrane rupture at or near term, we are investigating the addition of a foley catheter placed in the cervix to standard therapy (oxytocin administration) to decrease the time from the…
- Trial name
- NCT00290199
- Testing
- Transcervical Foley catheter
- Where
- 3 sites in United States
- Volunteers
- 169 people
- Sponsor
- University of Alabama at Birmingham
Induced Vaginal Delivery
Tension Versus Tension- Free Foley Balloon for Cervical Ripening
Foley balloons are commonly used as a mechanical method of cervical ripening for induction of labor. Foley balloons may be placed either under tension or without tension (tension-free).
- Trial name
- NCT05404776
- Testing
- Placement of Foley balloon for cervical ripening with tension., Placement of Foley balloon for cervical ripening without tension.
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cesarean Section
Ripening Interventions: Prostaglandins vs EASI Catheter
The primary aim of this randomized clinical trial is to compare the effect of misoprostol vs extra amniotic saline infusion via a catheter (EASI) for cervical ripening on the proportion of patients delivered by cesarean section…
- Trial name
- RIPE (NCT00383942)
- Testing
- Misoprostol, Catheter
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Loyola University
Cervical Ripening, Induction of Labor
Pharmacokinetic (PK) Study of the 200 Microgram (mcg) Misoprostol Vaginal Insert (MVI 200) in Women at Term Gestation (The MVI-PK Study)
The purpose of this study is to determine the pharmacokinetics (PK) of misoprostol acid for the MVI 200 in women requiring cervical ripening and induction of labor.
- Trial name
- NCT01283022
- Testing
- MVI 200
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ferring Pharmaceuticals
Preeclampsia, Labor, Premature
Use of Nitrous Oxide Donor for Labor Induction in Women With PreEclampsia
A randomized controlled trial (RCT) of nitric-oxide donor (NOD) isosorbide mononitrate (IMN) versus placebo as an adjuvant to misoprostol/ intra-cervical Foley bulb for induction of labor to decrease rate of cesarean deliveries…
- Trial name
- NOPE (NCT03171480)
- Testing
- Monoket Pill
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Ohio State University
Obesity, Labor, Induced
Oxytocin Dosage to Decrease Induction Duration
This is a randomized controlled trial in which women are allocated either 'high dose' or 'low dose' oxytocin infusions for induction of labour. The randomization is stratified by maternal body mass index.
- Conditions
- Obesity, Labor, Induced, Oxytocin
- Trial name
- OPS (NCT03140488)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Arizona
Pregnancy
A Randomized Comparison of Transcervical Foley Bulb With Vaginal Misoprostol to Vaginal Misoprostol Alone for Induction of Labor
A randomized, prospective trial will be offered to women admitted to the Roosevelt Hospital labor floor for labor induction. The hypothesis is that the simultaneous use of a foley bulb together with vaginal misoprostol will…
- Trial name
- NCT02566005
- Testing
- misoprostol, Foley bulb
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Pregnancy
Outpatient Foley Catheter Compared to Usual Inpatient Care for Labor Induction
Induction of labor, or causing labor to start before it otherwise starts spontaneously, is sometimes necessary as pregnancy progresses to ensure the safety of both mother and infant.
- Trial name
- NCT02546193
- Testing
- Foley catheter, Misoprostol
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Labor, Induced, Cervical Ripening
Prehospital Cervical Ripening Before Induction and the Maternal Experience
This is a randomized study evaluating the impact of pre-hospital cervical ripening with a transcervical Foley balloon before labor induction in full-term pregnancies on the length of inpatient labor induction and maternal…
- Trial name
- "PRIME" (NCT01641601)
- Testing
- Outpatient transcervical Foley balloon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Failed Induction of Labor
Modifying Cervical Bishop Scoring System
To have an early more precise way to predict failed induction in patients undergoing elective termination of pregnancy \& those more likely to undergo caesarian section,this will Spare patients with decreased chances of favorable…
- Trial name
- NCT02314260
- Testing
- bishop score calculation, Trans-vaginal ultrasound, Modified bishop score calculation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital