Clinical trials: Laceration Repair, Children
Laceration, Skin Wound
Comparison of microMend® Devices to Sutures in Closing Lacerations in Children
This study will gather information on the use of microMend® to repair lacerations in children and compare the efficacy of microMend® to sutures for laceration repair.
- Conditions
- Laceration, Skin Wound, Wound Heal
- Trial name
- NCT04557761
- Testing
- microMend®, Closure with Sutures
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Orange County
Children, Lacerations
Pain and Anxiety Management With Oral Narcotic for Pediatric Suture Repair
The purpose of this study is: To determine whether oral narcotic medication versus placebo improves the pain and anxiety scores for pediatric patients requiring laceration repair in the pediatric emergency department and…
- Conditions
- Children, Lacerations, Procedures, Child
- Trial name
- NCT01053637
- Testing
- hydrocodone/acetaminophen, Sugar water
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Baylor College of Medicine
Anxiety, Lacerations
Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department
Laceration repair can cause significant anxiety in children. As open wounds account for 21-25% of injuries in children presenting to the emergency department, the management of anxiety is of great importance.
- Trial name
- NCT02618772
- Testing
- Midazolam, Saline
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Infection, Laceration Repair
Nail Bed Repair With or Without Nail Bed Coverage
A randomized clinical trial conducted at Patel hospital, Karachi, from March 2024 to February 2025, to evaluate infection in patients undergoing nailbed repair with and without nailbed coverage, with minimum follow up for one…
- Conditions
- Infection, Laceration Repair, Laceration Repair, Children, Nail Bed Injury
- Trial name
- NCT06949189
- Testing
- Nail Bed Repair with Nail Bed Coverage, Nail Bed Repair without Nail Bed Coverage
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Patel Hospital, Pakistan
Lacerations
Gluing Lacerations Utilizing Epinephrine
Minor lacerations are a commonly treated injury in the paediatric emergency department . Over the past decade, standard closure of these lacerations has evolved from suture repair to closure with tissue adhesive (also referred to…
- Trial name
- GLUE (NCT01202487)
- Testing
- LET - Lidocaine Epinephrine Tetracaine
- Where
- Canada
- Volunteers
- 222 people
- Sponsor
- Children's Hospital of Eastern Ontario
Needlestick Injuries
Blunt Needles do Not Reduce Needlestick Injuries to Doctors During Suturing After Child-Birth
The hypothesis for this study is that use of blunt tipped needles used during the repair of an episiotomy (tear in the vagina after childbirth) will result in fewer needlestick injuries to the surgeon.
- Trial name
- NCT00536289
- Testing
- Blunt needle
- Where
- United States
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Procedural Anxiety
Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children
Dose-finding study to compare intranasal midazolam doses of 0.2, 0.3, 0.4 and 0.5 mg/kg in children undergoing laceration repair to achieve the following aims: Specific Aim #1: To determine the most effective dose of intranasal…
- Trial name
- NCT04586504
- Testing
- Intranasal midazolam
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Columbia University
Laceration Repair
Intranasal Dexmedetomidine Dose-finding Study
The most common injury prompting an emergency department (ED) visit in children is a cut (laceration) that requires repair using stitches or skin glue.
- Trial name
- NCT03957304
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Laceration of Skin, Distress, Emotional
Anxiolysis for Laceration Repair in Children
This is a 3-arm adaptive clinical trial to the optimal light sedative for reducing distress during laceration repair in children.
- Trial name
- ALICE (NCT05383495)
- Testing
- Dexmedetomidine, Midazolam Nasal Spray, Nitrous oxide
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Procedural Anxiety, Laceration of Skin
Virtual Reality for Anxiolysis During Laceration Repair in the Pediatric Emergency Room
The investigators propose a pilot study to examine the feasibility of utilizing immersive virtual reality to reduce procedural anxiety in children undergoing non-facial laceration repair in the Pediatric Emergency Department.
- Trial name
- NCT03475901
- Testing
- Virtual Reality App
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Anxiety, Laceration Repair
iPad as a Distraction Tool During Facial Laceration Repair
Children aged 2-12 presenting to the Rady Children's Hospital San Diego (RCHSD) emergency department with facial lacerations requiring suture repair will be eligible to participate in the study.
- Conditions
- Anxiety, Laceration Repair, Children
- Trial name
- NCT02217436
- Testing
- iPad, Standard Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Laceration Repair, Children, Hand Injuries
Cosmetic Outcome at 4 Months in Hand and Feet Lacerations in Children: Conservative Versus Suture Repair
Hand and feet lacerations are common in children with repair often requiring conscious sedation and needle sticks for repair. Growing evidence in adults reveal that many of these small lacerations do quite well cosmetically…
- Conditions
- Laceration Repair, Children, Hand Injuries, Foot Injuries
- Trial name
- NCT03321721
- Testing
- Suture for wound repair
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- St. Louis University
Tissue Adhesives, Laceration
Long-Term Outcome of Pediatric Traumatic Wound Repair: Suture Versus Tissue Adhesive
This project is an observational trial investigating wound cosmetic appearance after repair of traumatic skin lacerations in the head area of pediatric patients with two different approaches to skin closure: sutures versus tissue…
- Conditions
- Tissue Adhesives, Laceration, Sutures, Wounds and Injuries
- Trial name
- NCT03080467
- Where
- Switzerland
- Volunteers
- 386 people
- Sponsor
- University Children's Hospital, Zurich
Lacerations, Pain, Procedural
Comparison of Two Application Techniques for LET Gel
Comparison of anesthetic efficacy of Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel (LET) applied three times for 10 minutes each time vs.
- Conditions
- Lacerations, Pain, Procedural, LET
- Trial name
- NCT04203225
- Testing
- LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Children Requiring Sedation to Facilitate Laceration Repair
Volumes of Administration for Intranasal Midazolam
The purpose of this study is to determine exactly how much drug volume should be administered into each nare, so that the drug absorption can be maximized and the amount that runs out of the nose, or is swallowed, is minimized…
- Trial name
- NCT01948908
- Testing
- Intranasal midazolam
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Columbia University