Clinical trials: Laceration Repair
Dyspareunia, Perineal Tear
Rapidly Absorbing Polyglactin 910 Versus Poliglecaprone 25 for Laceration Repair
To evaluate the rates of dyspareunia with rapidly absorbing polyglactin 910 compared to poliglecaprone 25 using a validated sexual function questionnaire.
- Conditions
- Dyspareunia, Perineal Tear, Sutured Laceration
- Trial name
- NCT03184077
- Testing
- Laceration Repair with Polyglactin 910, Laceration Repair with poliglecaprone 25
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Supraspinatus Tear
Mesenchymal Stem Cells and Amniotic Membrane Composite for Supraspinatus Tendon Repair Augmentation
This is a non-randomized clinical trial conducted in a single tertiary hospital which investigates the efficacy of allogeneic adipose-derived mesenchymal stem cells and human amniotic membrane (AAdMSC-HAM) composite for…
- Trial name
- NCT04670302
- Testing
- Tendon repair procedure, Tendon repair augmented with AAdMSC-HAM composite
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Anterior Cruciate Ligament Tear
Bridge-Enhanced ACL Repair vs ACL Reconstruction
The goal of this trial is to compare the efficacy of the Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR™) technique with the current method of treatment for anterior cruciate ligament (ACL) injuries, ACL reconstruction.
- Trial name
- NCT02664545
- Testing
- BEAR Scaffold, Tendon Graft
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miach Orthopaedics
Rotator Cuff Tear, Tendon Injuries
Mesenchymal Stem Cells in Rotator Cuff Repair
Randomized clinical study involving 44 patients, evaluating the effect of mesenchymal cells on rotator cuff repair. The primary outcome will be post-operative MRI tendon integrity and secondary outcomes clinical assessment by the…
- Conditions
- Rotator Cuff Tear, Tendon Injuries, Mesenchymal Stem Cell
- Trial name
- NCT03362424
- Testing
- Mesenchymal stem cell, Rotator cuff repair
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Rotator Cuff Tear
Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
This study is a single-blind, randomized study evaluating the 6 month and 2 year outcomes of patients treated with arthroscopic rotator cuff repair using one of two techniques.
- Trial name
- RCRPRFM (NCT02256891)
- Testing
- PRFM, Double Row
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Shoulder Pain Chronic, Shoulder Pain
Arthroscopic Transosseous vs. Anchored Rotator Cuff Repair
This study will compare arthroscopic transosseous versus anchored rotator cuff repairs in terms of clinical outcomes, rotator cuff integrity, and cost-effectiveness.
- Conditions
- Shoulder Pain Chronic, Shoulder Pain, Rotator Cuff Tear, Rotator Cuff Injury
- Trial name
- NCT03797287
- Testing
- Tensor Tunnler, Anchor Rotator Cuff Repair
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rotator Cuff Tear
Influence of Intraoperative Repair Tension on Postoperative Healing of Full-thickness Rotator Cuff Tears
Relevant problems of rotator cuff repair: High retear rate after rotator cuff repair of 13%, despite regard of the criteria for "reparability" of a tear.
- Trial name
- TENS-RCT (NCT03318627)
- Testing
- Sterile Spring Scale
- Volunteers
- healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Muscle Atrophy, Proximal, Muscle Atrophy
Ultrasound for Rectus Femoris Measurement
Postoperative protocols for orthopedic procedures on the lower limb often require a period of immobilization to protect the surgical site.
- Conditions
- Muscle Atrophy, Proximal, Muscle Atrophy, ACL Tear, Quadriceps Muscle Atrophy
- Trial name
- NCT04105816
- Testing
- 892.1550 Ultrasonic pulsed doppler imaging system, Thigh circumference measurement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Robert Westermann
Rotator Cuff Tear
Impact of Postoperative Management on Outcomes and Healing of Rotator Cuff Repairs
Rotator cuff tears are seen in 40% of subjects over age 50 57, with a prevalence known to increase with each decade of life 51. Each year rotator cuff disorders lead to 4.5 million physician visits, 40,000 inpatient surgeries…
- Trial name
- NCT01383239
- Testing
- Immediate Postoperative Therapy, Delayed Physical Therapy
- Where
- 9 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Knee Medial Meniscus Tears, Meniscus Lesion
Predictors of Early Success From Circumferential Compression STITCH Meniscal Repairs
This is a retrospective study of meniscal tear repairs at least one-year post repair status. All patients were treated with Ceterix NovoStitch devices.
- Conditions
- Knee Medial Meniscus Tears, Meniscus Lesion, Meniscus; Rupture, Bucket Handle, Meniscus Disorder
- Trial name
- STITCHRetro (NCT03097744)
- Testing
- Ceterix NovoStitch
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew, Inc.
Rotator Cuff Tear
Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair
1. Treatment of rotator cuff tear The rotator cuff tear is the most demanding part of the shoulder surgery. Rotator cuff degeneration is thought to be the largest cause of rotator cuff tear.
- Trial name
- VITCRCR (NCT02992028)
- Testing
- Intravenous Nutrition (Vitamins) injection, Intravenous Saline injection
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Himchan Hospital
Complete Tear, Ankle, Lateral Ligament, Postural Balance
Assessment of Balance and Function After Lateral Ankle Ligament Repair
Approximately 85% of ankle injuries are lateral region injuries.Surgical repair of lateral ligaments is indicated if there is more than 20 degrees of varus or more than 15 mm translation, if conservative treatment is ineffective…
- Conditions
- Complete Tear, Ankle, Lateral Ligament, Postural Balance, Physical Functional Performance
- Trial name
- NCT04788225
- Testing
- Balance assessment, Functionality assessment, Performance assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Laceration Face, Wound Heal
Honey Versus Povidone-iodine on Laceration Wounds
This study evaluates healing time in usage of honey and povidone-iodine over paraffin gauze as dressings in the treatment of acute laceration wounds.
- Conditions
- Laceration Face, Wound Heal, Wounds and Injuries, Laceration Arm
- Trial name
- NCT03641053
- Testing
- Honey, Povidone-iodine, Paraffin gauze
- Where
- Indonesia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- S.K. Lerik General Hospital
Anxiety, Lacerations
Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency Department
Laceration repair can cause significant anxiety in children. As open wounds account for 21-25% of injuries in children presenting to the emergency department, the management of anxiety is of great importance.
- Trial name
- NCT02618772
- Testing
- Midazolam, Saline
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Rotator Cuff Tear
Decellularized Human Placental Extracellular Matrix Tissue for Rotator Cuff Repair Augmentation
The rotator cuff is a set of muscles and tendons that help move the shoulder. Tears in the rotator cuff are common, particularly as people age. Consequently, rotator cuff repair surgeries are common, as well.
- Trial name
- ECMRCR (NCT07027735)
- Testing
- Rotator Cuff Repair with Allograft Patch, Rotator Cuff Repair with No Augmentation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Columbia University
Laceration of Skin
Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs
Diphenhydramine, when injected locally, has been shown to achieve a certain level of local anesthesia. It has been documented for use in simple bedside procedures, however there is a gap in knowledge in its comparison to…
- Trial name
- NCT06910241
- Testing
- Lidocaine, Diphenhydramine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Vaginal Discharge, Perineum; Rupture
Efficacy and Safety of the Application of Local Anaesthetic in Spray to Repair of 1st- 2nd Perineal Lacerations
Randomized controlled trial aimed at evaluating the efficacy and safety of the use of a local anesthetic spray, commonly used in clinical practice as off-label, during the suturing of perineal lacerations in post-partum…
- Conditions
- Vaginal Discharge, Perineum; Rupture, Analgesia
- Trial name
- LISPRAY (NCT05201313)
- Testing
- Lidocaine Hydrochloride, Mepivacaine Injection
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair
To compare the functional and anatomical outcomes, and patient satisfaction and compliance between two different postoperative immobilization methods - abduction shoulder brace versus simple arm sling - following 2 common…
- Trial name
- NCT03488433
- Testing
- Abduction brace, Antirotation sling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Anterior Cruciate Ligament Tear
Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique
The purpose of the study is a clinical evaluation with special regard to magnetic resonance imaging and functional performance at least one year after injury / surgery in all three groups (subjects who underwent InternalBrace…
- Trial name
- NCT02760589
- Where
- Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- AUVA
Facial Laceration, Anxiety
Intranasal Fentanyl in Combination With Midazolam Versus Midazolam Alone for Pediatric Facial Laceration Repair
The purpose of the study is to compare the effectiveness of a combination of intranasal fentanyl and intranasal midazolam to intranasal midazolam alone for analgesia and anxiolysis in patients presenting for facial laceration…
- Trial name
- NCT04745260
- Testing
- Intranasal Fentanyl Spray and Intranasal Midazolam Spray, Intranasal Midazolam Spray
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin