Clinical trials: Lactate
Xerosis Cutis
Comparison of 12% Ammonium Lactate and 10% Urea Cream in Geriatric With Xerosis Cutis
This study aims to compare the efficacy and safety between moisturizing cream containing 12% ammonium lactate and 10% urea in geriatric with xerosis cutis.
- Trial name
- NCT04127513
- Testing
- Ammonium Lactate, Urea
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Laxity; Skin
Assess Impact of Poly-L-lactic Acid on GLP1 Subjects
Clinical trial to evaluate treatments of double-dilute poly-L-lactic acid on abdominal skin laxity in GLP1 patients versus non GLP1 patients.
- Trial name
- NCT07217743
- Testing
- Sculptra Aesthetic
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Skin Laxity
Retrospective Study of the Safety and Efficacy of PLLA for Skin Flaccidity in Labia Majora and/or Pubis Region
Phase IV, retrospective, single-center, clinical trial, chart review to evaluate the safety and efficacy of poly-L-l-lactic acid [PLLA-SCA, Sculptra®] in women who underwent at least one treatment for skin flaccidity of the labia…
- Trial name
- NCT05940038
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Galderma Brasil Ltda.
Critical Illness, D-Lactate
Diagnostic And Prognostic Value Of D-Lactate And Scube-1 Levels In Critically Ill Patients
The investigators aimed to investigate the diagnostic and prognostic levels of D-Lactate and SCUBE-1 in critically ill patients being admitted to the emergency department.
- Conditions
- Critical Illness, D-Lactate, SCUBE-1
- Trial name
- NCT06704438
- Testing
- D-Lactate
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Muscle Oxygenation, Lactate
Capacitive Resistive Electric Transfer Therapy on Muscle Recovery
This study aims to evaluate the effectiveness of Capacitive Resistive Electric Transfer (CRET) therapy combined with post-competition massage in the recovery and muscle function of professional athletes.
- Conditions
- Muscle Oxygenation, Lactate, Anaerobic Exercise
- Trial name
- NCT06906146
- Testing
- CRET therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Postoperative Inflammation
A Comparative Study of Volume Replacement With HES 130/0.4 Versus Ringer's Lactate (RL) Regarding Their Effects on Inflammatory Biomarkers (Cytokines and Matrix Metalloproteinases) Responses to Major Abdominal Surgery.
Various stimuli such as trauma, infection and major surgery may alter the physiologic immune balance and initiate systemic inflammatory processes.
- Trial name
- NCT01880190
- Testing
- Ringer's Lactate, HES 130/0.4 and Ringer's Lactate
- Where
- Greece
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Recovery Methods, Exercise Training
Effects of Different Recovery Methods on Lactic Acid Removal, Flexibility, Strength, and Endurance
The aim of this study is to compare these three different recovery methods following a single bout high-intensity interval exercise program with each other in terms of blood lactate clearance, muscle flexibility, muscle strength…
- Trial name
- NCT03563430
- Testing
- Active Recovery Group, Self-Massage with Foam Roller Group, Neuromuscular Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Biruni University
Muscle Fatigue
Effect of Kinesio Taping in Muscle Fatigue
The aim of this study was to determine the effect of Kinesio taping on lactic acid in an running anaerobic test.
- Trial name
- NCT02495428
- Testing
- Kinesio Tape Method
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CEU San Pablo University
Healthy, Lactate Blood Increase
The Lactate Project: Investigating the Impact of Lactate to Preserve Vital Organ Blood Supply and Function in Heart and Brain
The aim of the proposed study is to investigate the effect of increased plasma lactate concentrations on the heart and brain's metabolism of other energy sources, primarily glucose in the brain and glucose and FFA in the heart.
- Trial name
- NCT06665763
- Testing
- Sodium Lactate Solution
- Where
- 2 sites in Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Gingivitis
Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use
The objective of this six-month clinical research study is to evaluate the clinical efficacy of a new mouthwash on helping prevent gum problems (gingival index scores ) in adults as compared to a control mouthwash.
- Trial name
- NCT06770114
- Testing
- Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash, PhosFlur Mouthwash
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Hemodilution, Hemorrhage
Proving Hemodilution in a Human Model for Class I Hemorrhage
This study is a randomized control trial in volunteer blood donors to quantify the effect of blood loss and subsequent crystalloid infusion on hemoglobin and markers of resuscitation such as base deficit and lactate.
- Conditions
- Hemodilution, Hemorrhage, Shock, Wounds and Injuries
- Trial name
- NCT02318355
- Testing
- normal saline, lactated ringers
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Skin Aging
Poly-L-lactic Acid for Skin Quality
Anecdotal evidence suggests that patients' skin quality may improve as a result of poly-L-lactic acid injection. While this is not the primary goal of such treatments it is often seen and described as so called "Sculptra glow".
- Trial name
- NCT02003833
- Testing
- Poly-L-lactic acid
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sadick Research Group
Lactate Blood Increase, Exhaustion - Physiological
Pilot Study to Examine the Acute Impact of Veillonella Supplementation on Exercise and Lactate Responses
The purpose of this study is to assess the health and performance outcomes associated with supplementation of Veillonella atypica.
- Trial name
- VP (NCT05816291)
- Testing
- Time to Exhaustion at velocity at VO2max
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Sports Injury
Clinical Trial for Vespa Amino Acid Mixture (VAAM®)
ATP is generated mainly through anaerobic metabolism during strenuous exercise, which is then followed by the generation of lactic acid.
- Trial name
- NCT03121040
- Testing
- Vespa amino acid mixture
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shanghai Meiji Health Science and Technology Co., Ltd.
Healthy
Pharmacokinetics and Pharmacodynamics of Fructose
The purpose of this study is to determine whether sucrose vs high fructose corn syrup from a soft drink results in differences in various metabolic byproducts such as fructose, glucose, serum uric acid, triglyceride and lactate.
- Trial name
- NCT00661947
- Testing
- Dr Pepper sweetened with sucrose or high fructose corn syrup
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Florida
Exercise Training
Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism
Introduction This study investigates the effects of different intensities of indoor cycling on various health measures. Participants will perform a maximal cycling test to determine their maximal fitness - a strong predictor of…
- Trial name
- CEX (NCT06398548)
- Testing
- Control Group, Moderate Intensity Continuous Training, Heavy Intensity Continuous Training
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Renal Function Test, Urine Output, Lactate Level
Dopamine and Norepinephrine Infusion With Restricted Hydration
This study was designed to assess the effect of adding dopamine infusion in addition to restrictive hydration combined with noradrenaline infusion on intraoperative serum lactate levels as an indicator for tissue hypo perfusion…
- Trial name
- NCT03780686
- Testing
- Norepinephrine, dopamine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Skin Texture
Characterization of Skin and Facial Fat Pad Thickness Changes Following Microneedling Radiofrequency With and Without Topical Poly-L-Lactic Acid for Facial Rejuvenation
The purpose of this study is to evaluate whether microneedling RF subcutaneous fat pad thickness in the temple, submental, and cheek regions, to determine whether the addition of topical PLLA after microneedling RF alters or…
- Trial name
- NCT07261527
- Testing
- microneedling RF treatment, PLLA, Sterile Water as control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hygiene
Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Photo Avaluation
The purpose of this study is to demonstrate the absence of photoirritation and photosensitization potential of the product Dermacyd PHDETINBACK Sweet Flower.
- Trial name
- NCT00785720
- Testing
- Dermacyd PH_DETINBACK (Lactic Acid)
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Sanofi
HIV Infections
Use of Muscle Spectroscopy to Evaluate Mitochondrial Dysfunction in HIV-Infected Patients
The purpose of this study is to see if magnetic resonance spectroscopy (MRS) can be used to detect damage to the mitochondria in HIV-infected patients taking nucleoside reverse transcriptase inhibitor (NRTI) drugs.
- Trial name
- NCT00036478
- Where
- 8 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)