Clinical trials: Lactation Disorders
Growth, Body Composition
Effect of Target Fortified Human Milk on the Growth Quality of Very Preterm Infants (TargetFort)
It is reported that the standard method for fortification of human milk (HM) overestimates the energy and protein densities of HM (Macedo MHNP 2018), thus originating infant undernutrition (Macedo AJP 2018).
- Conditions
- Growth, Body Composition, Prematurity, Breast Milk Collection
- Trial name
- TargetFort (NCT04400396)
- Testing
- standard HM fortification, target HM fortification
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Breastfeeding, Exclusive, Fatigue
MBSR and NLP, Postpartum Breastfeeding and Depression
The postnatal period is a risky period in which mothers experience regressive and progressive changes and rapid biopsychosocial changes.
- Conditions
- Breastfeeding, Exclusive, Fatigue, Sleep, Postpartum Depression
- Trial name
- postpartum (NCT06628986)
- Testing
- MBSR, NLP, control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aysegul Kilicli
Lactation Suppressed
Cabergoline for Lactation Inhibition After Early Second-Trimester Abortion or Pregnancy Loss
Breast pain following second-trimester abortion is common. Breast engorgement and milk leakage following second-trimester perinatal loss and abortion can cause both physical pain and emotional distress.
- Trial name
- eLISTA (NCT06029673)
- Testing
- Cabergoline 1 MG
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Stanford University
Ventricular Tachyarrhythmia, Sudden Cardiac Death
Domperidone and Risk of Serious Cardiac Events in Postpartum Women
The purpose of this study is to determine whether the use of domperidone is associated with an increased risk of serious cardiac events among postpartum women in the six months following delivery.
- Conditions
- Ventricular Tachyarrhythmia, Sudden Cardiac Death, Lactation, Breast Feeding
- Trial name
- NCT04024865
- Testing
- Domperidone, No domperidone
- Where
- Canada
- Volunteers
- 184,929 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
HIV Infections
Breastfeeding, Antiretroviral, and Nutrition Study
This is a comparative clinical trial among HIV-infected women and their infants to determine: 1. the benefit of nutritional supplementation given to women during breastfeeding 2.
- Trial name
- NCT00164736
- Testing
- Maternal zidovudine/lamivudine/lopinavir-ritonavir, Infant nevirapine, Maternal protein and calorie supplement
- Where
- Malawi
- Volunteers
- 2,369 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Preterm Infant, Lactation
Melatonin Degradation Rate in Human Milk
Our long term hypothesis is that giving premature infants breast milk that was pumped during the night and has high concentration of melatonin will improve outcome of several clinical conditions related to premature infants.
- Trial name
- NCT03591341
- Testing
- melatonin level in pumped breast milk
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Breastfeeding
Maternal Obesity and Breastfeeding Performance
Investigators propose this study in order to answer the following research question: An educational intervention and breastfeeding support at postpartum will increase the frequency and total breastfeeding duration in the…
- Trial name
- NCT02756169
- Testing
- Intervention
- Where
- Mexico
- Volunteers
- 261 people
- Sponsor
- Universidad Iberoamericana A.C., Mexico
Malnutrition in Pregnancy, Other Disorders of Breast and Lactation Associated With Childbirth
Evaluation of Effectiveness of Cell Phone Technology as Community Based Intervention to Improve Exclusive Breast Feeding
Primary hypotheses In a hospital-based CRCT, cell phone lactational counseling starting in the third trimester of pregnancy to 24 weeks after delivery will improve the prevalence of EBF by 7.5 % (7.5% increase in EBF by…
- Trial name
- BFC (NCT01383070)
- Testing
- Lactational Counseling by Cell phone
- Where
- India
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- Lata Medical Research Foundation, Nagpur
Antibody Immune Profile
Study of the Development of Human Immune System of Newborns by Antigen Chips
The immune system is a dynamic, constantly evolving network. Excluding autoimmune diseases, healthy individuals are also known to have a large number of circulating antibodies that can recognize proteins of their own tissues.
- Trial name
- NCT00843648
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Maternal Health Services, Infant, Newborn
Comparing Integrative Midwife-led vs. Fragmented Inpatient Postpartum Care: Impact on Satisfaction and Transition to Motherhood
The goal of this clinical trial is to compare two different forms of postnatal care to find out which is most beneficial for mothers and their children after birth and with which they are most satisfied.
- Conditions
- Maternal Health Services, Infant, Newborn, Postnatal Care, Breast Feeding
- Trial name
- SMILE (NCT07077941)
- Testing
- Integrative care
- Where
- Austria
- Volunteers
- 784 people
- Sponsor
- Medical University of Vienna
Influenza
Post-Partum Immunization With Live Attenuated Influenza Vaccine (LAIV) or Trivalent Influenza Vaccine (TIV) in Post-Partum Breast Feeding Women
The purpose of this research study is to learn more about the safety of 2 licensed flu vaccines, nasal spray and flu vaccine shot, in mothers and their infants, when given to women who are breastfeeding and to compare the immune…
- Trial name
- NCT01181323
- Testing
- Cold-adapted live attenuated influenza virus vaccine, trivalent, Trivalent inactivated influenza vaccine
- Where
- 6 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Breastfeeding, Anxiety Disorders
The Effect of Breastfeeding Support Provided Via Video-conferencing
A randomized control trial was made to examine the effects of breastfeeding support given by the video-conferencing method in the early postpartum period on anxiety, breastfeeding self-efficiency, and newborn outcomes.
- Conditions
- Breastfeeding, Anxiety Disorders, Neonatal Outcomes
- Trial name
- NCT04929561
- Testing
- Video-conferencing group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Obesity, Metabolic Syndrome
Milk Types and Fish Oil in 9- to 12-Month-Old Infants
The objective of this intervention study is to examine the effect of whole cow's milk versus infant formula as primary milk sources with or without supplements of n-3 LCPUFA for growth, nutritional status, development, risk…
- Conditions
- Obesity, Metabolic Syndrome, Growth, Blood Pressure
- Trial name
- NCT00379171
- Testing
- Cow's milk with fish oil, Cow's milk without fish oil, Formula with fish oil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hiv
Evaluation of Pre-exposure Prophylaxis Cascade in Pregnant and Breastfeeding Women in Cape Town (Formative Study)
The overarching goal of this proposal is to evaluate the feasibility and acceptability of integrating PrEP into antenatal and postnatal care, to describe the cascade in women initiating PrEP in this setting, and to evaluate the…
- Trial name
- PrEP-PP (NCT03826199)
- Testing
- TDF-FTC, Counselling on PrEP in antenatal and postnatal care
- Where
- South Africa
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Breastfeeding, Feeding Disorder Neonatal
Effect of Supplemental Feeding Tube Devices in Breastfeeding Success and Mother's Breastfeeding Self-Efficacy
The research will be carried out as a randomized controlled experimental design to evaluate the effectiveness of the breastfeeding support system to increase sucking success in premature infants receiving care in the NICU and…
- Trial name
- NCT05802095
- Testing
- Supplemental Feeding Tube Device
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Exclusive Breastfeeding Rates, Neonatal Jaundice
BEST ABCs: Benefits and Effectiveness of Support Offered Through A Breastfeeding Clinic Study
Currently, healthy mothers willing to breastfeed their babies are discharged from the hospital on an average 2 days after a vaginal delivery or 3.5 days after a C-section, at a time where breastfeeding is far to be well…
- Trial name
- BEST ABCs (NCT02043119)
- Testing
- Breastfeeding Clinic
- Where
- Canada
- Volunteers
- 472 people
- Sponsor
- Ottawa Hospital Research Institute
Non-Diabetic, Females Who Are Not Pregnant or Breast Feeding
The Wellness Transformation Network Pilot Study
The purpose of the study is to establish a Standard Operating Procedure (SOP) for the screening of pathologies associated with prediabetes and type 2 diabetes.
- Trial name
- NCT05314036
- Testing
- Standardized test meal
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- SciMar Ltd.
Healthy Diet, Health Behaviour
Effectiveness of Educational Intervention on Sustainable Breastfeeding: The GREEN MOTHER Project
Breastfeeding is the healthiest form of nutrition for the baby and is recommended to use exclusive breastfeeding (EB) until 6 months.
- Conditions
- Healthy Diet, Health Behaviour, Environmental-Pollution-Related Condition, Mothers
- Trial name
- NCT05729581
- Testing
- The educational programme on sustainable and healthy diet and breastfeeding
- Where
- Spain
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Scapular Dyskinesis
Effects of Motor Control Retraining and Scapular Stabilization Exercises in Females With Scapular Dyskinesia.
To evaluate the combined effects of motor control retraining and scapular stabilization exercises on pain reduction, muscle strength improvement, and functional enhancement in breastfeeding females diagnosed with scapular…
- Trial name
- NCT07576426
- Testing
- motor control retraining, scapular stabilization exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Covid19, Exclusive Breastfeeding
COVID-19 Breastfeeding Guideline for African-Americans
Newborns and infants receive passive natural immunity through maternal antibodies present in breastmilk to fight infections caused by viruses such as the COVID-19, until they develop active immunity by illness or vaccination.
- Trial name
- COVID-BF (NCT04476940)
- Testing
- COVID-19 Breastfeeding Support
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College