Clinical trials: Lactation Disorders
Prematurity, Nutrition
Nutritional Content of Breast Milk From Mothers of Premies
The purpose of this study is to determine the correlation, if any, between the nutritional content of breast milk pumped by the mothers of very low birth weight (VLBW) infants in the neonatal intensive care unit (NICU) and the…
- Trial name
- NCT01050192
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Prematurity
Impact of Different Electric Pumping Modalities on Milk Volume Production in Mothers of Preterm Infants
Initiating and sustaining breastfeeding are common challenges in neonatal units. It is known that hindmilk expressed at the end of the expression session has a higher fat content.
- Trial name
- NCT01802047
- Testing
- milk expression with electric pump
- Where
- Israel
- Sponsor
- Tel-Aviv Sourasky Medical Center
Infant Nutrition Disorders
Breastfeeding Duration and Tongue-tie in Neonates.
The goal of this observational study is to examine how performed frenotomy in term-born infants influences the breastfeeding duration.
- Trial name
- NCT05946590
- Testing
- Frenotomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Lactation Induced
Effect of OMEGA 3 Fatty Acids on Lactation Period
The World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) recommend that babies be exclusively breastfed for the first 6 months from birth.
- Trial name
- NCT06111378
- Testing
- fish oil, linseed oil, walnut oil
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Obesity, Water; Lack of
Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months
This study aims to assess the impact of a brief home-visiting module, called "Family Spirit Nurture" (FSN), on American Indian (AI) parent feeding practices associated with increased risk for early childhood obesity, with a…
- Conditions
- Obesity, Water; Lack of, Breast Feeding, Tooth Erosion
- Trial name
- NCT03101943
- Testing
- Family Spirit Nurture (FSN), Control Program, Water Delivery
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
COVID-19
Multisite Observational Maternal and Infant Study for COVID-19
This is an observational, non-interventional, prospective cohort study designed to collect clinical information and specimens to evaluate the immune responses from pregnant individuals and postpartum individuals and their infants…
- Trial name
- MOMI-Vax (NCT05031468)
- Testing
- Licensed or EUA SARS-CoV-2 vaccine
- Where
- 10 sites in United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Emory University
Lactation, Bone Diseases, Endocrine
African-American Bone Metabolism and Lactation Study
The primary aim of this study is to obtain measures of amino-terminal telopeptides of procollagen 1 (P1NP), a marker of bone formation, in lactating and non-lactating post-partum African-American women both at 6-8 and at 12-14…
- Trial name
- NCT00785824
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Gestational Diabetes Mellitus
Diet, Exercise, and Breastfeeding Intervention Program for Women With Gestational Diabetes (DEBI Trial)
The primary aim of this study is to evaluate whether a lifestyle intervention of diet, exercise, and breastfeeding is associated with decreased postpartum weight retention and reduced plasma glucose levels, measured at 6-weeks…
- Trial name
- DEBI (NCT00460018)
- Testing
- Diet, Exercise, and Breastfeeding Intervention
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Kaiser Permanente
Atopic Dermatitis, Food Allergies
Probiotic Supplementation in Breastfed Newborn Infants
The purpose of this study is to investigate the dose of a probiotic supplement (Bifidobacterium longum subsp. infantis) required to achieve predominant gut colonization in healthy newborn, breastfed infants.
- Trial name
- NCT02286999
- Testing
- B. infantis
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emanual Maverakis, MD
Child Nutrition, Stunting
Impact Evaluation of a Social Franchise Model for Improving Infant and Young Child Feeding and Child Nutrition in Vietnam
Alive \& Thrive is an initiative that aims to improve infant and young child feeding practices and reduce childhood stunting. In Vietnam, Alive \& Thrive's primary intervention is implemented through a social franchise linked…
- Conditions
- Child Nutrition, Stunting, Exclusive Breastfeeding, Complementary Feeding
- Trial name
- NCT01676623
- Testing
- Standard government health services, Alive & Thrive IYCF franchise services, Mass media campaign
- Where
- Vietnam
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Pediatric Obesity, Recruitment
The BEACH Interview Study- Pregnant and Breastfeeding Mothers
Interview pregnant and breastfeeding mothers in the Gainesville, FL area to optimize; clinical study recruitment and retention, patient-centered outcomes, and stool collection procedures.
- Trial name
- BEACH (NCT03036696)
- Testing
- Pregnant Mothers Interview, Breastfeeding Mothers Interview
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Florida
Multiple Sclerosis
Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis
This study will evaluate whether ofatumumab is excreted at quantifiable levels and at which concentrations in breast milk of lactating women with RMS).
- Trial name
- KATHAROS (NCT06444113)
- Testing
- Ofatunumab
- Where
- 15 sites in United States, Germany and 3 more
- Volunteers
- 24 people
- Sponsor
- Novartis Pharmaceuticals
Vitamin B 12 Deficiency
Cobalamin Supplementation During Infancy; Effect on B-vitamin Status, Growth and Psychomotor Development
Adequate levels of vitamin B12 (cobalamin) is necessary for normal growth and development in infants. We have earlier investigated cobalamin status in healthy children and we observed metabolic evidence of impaired cobalamin…
- Trial name
- NCT00479479
- Testing
- Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
- Where
- Norway
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Postpartum, Pregnancy Related
Postpartum Care Timing: A Randomized Trial
The purpose of this study is to determine if shortening the time to initial postpartum visit from six weeks to two weeks can improve clinic visit attendance and decrease usage of the emergency department.
- Trial name
- PUnCTuAL (NCT03733405)
- Testing
- Postpartum Visit at 6 Weeks, Postpartum Visit at 2 Weeks
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Childhood Obesity, Breastfeeding
Breastfeeding in Infancy and Food Intake in Preschool-Aged Children
The purpose of this study is to compare female, preschool-aged children breastfed during infancy to female, preschool-aged children bottle-fed during infancy in their ability to adjust calorie intake in response to internal…
- Trial name
- NCT00994487
- Testing
- High Energy Density Preload, Low Energy Density Preload
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Anxiety, Amount of Breast Milk
The Effect of Virtual Reality Glasses on Anxiety Level and Breast Milk Amount
Pain, anxiety, nausea, vomiting, etc. In coping with symptoms, virtual reality glasses are recommended as a distraction application.
- Trial name
- NCT06153628
- Testing
- Virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Pregnancy Related, Pregnancy Loss
Microbiome and Malnutrition in Pregnancy
This study is being conducted to investigate how a mother's nutritional status and her gut microbiome during pregnancy contribute to the birth outcomes and health of her baby.
- Conditions
- Pregnancy Related, Pregnancy Loss, Pregnancy Complications, Pregnancy; Parasitic Disease
- Trial name
- MMIP (NCT04992104)
- Where
- 2 sites in Canada
- Volunteers
- 800 people
- Sponsor
- The Hospital for Sick Children
Prematurity, Low Birth Weight
Paternal Involvement in Nursing Guidance and Breastfeeding Self-Efficacy in Mothers of High-Risk Newborns
This study aims to evaluate whether a structured nursing guidance program that increases fathers' participation in the care of hospitalized high-risk newborns improves maternal outcomes compared with routine nursing care.
- Conditions
- Prematurity, Low Birth Weight, Respiratory Distress Syndrome, Newborn, Neonatal Hyperbilirubinemia
- Trial name
- NCT07834008
- Testing
- step-by-step parent education, active father participation in breastfeeding support
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Crohn's Disease, Ulcerative Colitis
Assessing the Drug Exposure Risk of Infants Breastfed by Women With Inflammatory Bowel Disease
Breastfeeding is beneficial to both mother and baby. However, many breastfeeding women are affected by long-term health conditions and need to take medications.
- Conditions
- Crohn's Disease, Ulcerative Colitis, Healthy Controls
- Trial name
- NCT03397108
- Testing
- The IBD group was divided into 2 subgroups: with or without anti-TNF antibody use
- Where
- 2 sites in Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
HIV Infections
Tenofovir Gel in Pregnancy and Lactation
Tenofovir 1% gel is an investigational vaginal microbicide intended to reduce the risk of transmission of HIV. Pregnant women and mothers who have recently given birth often maintain sexual activity, and research has shown that…
- Trial name
- NCT01136759
- Testing
- Tenofovir 1% gel
- Where
- 2 sites in United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)