Clinical trials: Language
Cochlear Implant
Pediatric Image-Guided Cochlear Implant Programming
Cochlear implants are surgically implanted devices which restore the ability to hear to the hearing impaired. Recent literature has indicated that children receiving cochlear implants (CIs) often have dramatically improved speech…
- Trial name
- NCT03886168
- Testing
- Signal processing intervention of a biomedical device
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Vanderbilt University Medical Center
Language Development, Behavior, Child
Literacy Promotion for Latinos Study
This study tests the extent to which tailored outreach text messages that provide a cue to action and an intervention that enhances access to poverty-reducing resources, in combination with standard primary care literacy…
- Conditions
- Language Development, Behavior, Child, Parenting, Literacy
- Trial name
- NCT04609553
- Testing
- Usual care including ROR, Text messages, Connection to community resources
- Where
- United States
- Volunteers
- 662 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Stuttering, Stuttering, Childhood
Speech Processing in Stuttering
This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech.
- Conditions
- Stuttering, Stuttering, Childhood, Stuttering, Adult
- Trial name
- NCT04929184
- Testing
- Speech and non-speech tasks
- Where
- 2 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Autism Spectrum Disorders
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
Background: Some children with autism spectrum disorders (ASD) do not have normal sleep cycles. Some of these children spend very little time in the rapid eye movement (REM) stage of sleep.
- Trial name
- NCT01887132
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Mental Health (NIMH)
Bibliotherapy
Guided Self-help for Common Mental Disorders
Common mental disorders (CMDs) like depression and anxiety account for a large proportion of disability worldwide. Access to effective treatments like cognitive-behavioral therapy (CBT) is limited and has not reduced the public…
- Trial name
- DWM (NCT04870099)
- Testing
- Doing What Matters in Times of Stress: An Illustrated Guide
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Indiana University
Rehabilitation of Speech and Language Disorders, Speech Disorders
MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments
This study will evaluate the ability of MyoVoice to replace natural speech. Referred to generally as an Augmentative and Alternative Communication (AAC) device, MyoVoice uses electrical signals recorded non-invasively from speech…
- Conditions
- Rehabilitation of Speech and Language Disorders, Speech Disorders, Speech, Alaryngeal, Communication Aids for Disabled
- Trial name
- NCT04762043
- Testing
- Experimental System: MyoVoice, Reference System: Electrolarynx
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Aphasia, Stroke
Post-Stroke Aphasia and Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Study
In this study the investigators will examine the efficacy of navigated excitatory repetitive transcranial magnetic stimulation (nerTMS) for the treatment of post stroke aphasia.
- Trial name
- PART (NCT01512264)
- Testing
- Magstim SuperRapid
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Alabama at Birmingham
Aphasia, Acquired
Word Retrieval in the Wild in People With Post-Stroke Aphasia
People with post-stroke aphasia (PWA) suffer from anomia, a condition where they know what they want to say but cannot retrieve the words.
- Trial name
- NCT05338216
- Testing
- Traditional EMA, Micro-Interaction EMA
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northeastern University
Primary Progressive Aphasia
Communication Bridge 2
This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild Primary Progressive Aphasia (PPA).
- Trial name
- CB2 (NCT03371706)
- Testing
- Communication Bridge™, Evidence-Based Impairment Focused
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- University of Chicago
Diabetes, Deafness
American Sign Language-Accessible Diabetes Education
ASL-ADE will evaluate the efficacy of an ASL-interpreted diabetes educational intervention to the end of improving the health literacy of the target population and addressing their disparate health outcomes.
- Trial name
- ASL-ADE (NCT03980808)
- Testing
- American Sign Language-Accessible Diabetes Education, Control Intervention
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Hearing Loss
Littlears Auditory Questionnaire: Validation Study in CI Children
The LittlEARS Auditory Questionnaire is designed to assess the development of the auditory behavior in children during the first two (hearing) years.
- Trial name
- LittlEars (NCT00785707)
- Where
- 5 sites in United States
- Volunteers
- 31 people
- Sponsor
- Med-El Corporation
Aphasia
Effect of Verb Network Strengthening Treatment (VNeST) on Lexical Retrieval in Aphasia
The purpose of this study is to evaluate the effect of Verb Network Strengthening Treatment (VNeST) on the ability to produce sentences and connected speech in persons with aphasia.
- Trial name
- VNeST (NCT01300624)
- Testing
- Verb Network Strengthening Treatment
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Stuttering, Adult
Bihemispheric Transcranial Direct Current Stimulation* on Speech Fluency
It will be determined whether bihemispheric stimulation (anodal to the left IFG and cathodal to the right IFG) is used with fluency-facilitating conditions for 5 consecutive days in individuals with stuttering and whether there…
- Trial name
- TDCS (NCT06278233)
- Testing
- Transcranial direct current stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Biruni University
Substance Use, Substance Abuse
Data-driven Identification for Substance Misuse
The investigators propose to develop an open-source, publicly available machine learning model that health systems could download and apply to their electronic health record data marts to screen for substance misuse in their…
- Conditions
- Substance Use, Substance Abuse, Substance-Related Disorders
- Trial name
- NCT03833804
- Testing
- Processing of clinical notes in the EHR data collected during routine care
- Where
- United States
- Volunteers
- 64,996 people
- Sponsor
- University of Wisconsin, Madison
Social Anxiety Disorder, Selective Mutism
Treatment of Social Anxiety Disorder and Selective Mutism
This study is to assess the efficacy of a brief, 11-week, manualized Taming Sneaky Fears for Social Anxiety Disorder (SAD) and/or Selective Mutism (SM) child and parent group Cognitive Behavioural Therapy (CBT) treatment…
- Trial name
- SAD&SMTRMT (NCT02554929)
- Testing
- Taming Sneaky Fears, Parent Psycho-education and Child Socialization
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- The Hospital for Sick Children
Autism
Autologous Cord Blood Stem Cells for Autism
Evaluate the efficacy of one infusion of stem cells from autologous umbilical cord blood in patients with autism over six months after infusion as measured by changes in expressive and receptive language.
- Trial name
- NCT01638819
- Testing
- Autologous Cord Blood Stem Cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sutter Health
Primary Progressive Aphasia
HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms
This study aims to evaluate the effectiveness of a therapy called High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for the treatment of the language deficits experienced by people with a type of Primary…
- Trial name
- NCT03805659
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Medical College of Wisconsin
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT05325333
- Testing
- Retrieval-based word learning: Expanding retrieval practice schedule, Retrieval-based word learning: Standard retrieval practice schedule
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Peer Influence
Penetrating the Classroom Social Network for Children With Language Impairment Via Peer Mediated Intervention
This exploratory experiment is designed to determine the extent to which the socialization experiences and social, behavioral, and linguistic skills of preschoolers with language impairment (LI) can be improved.
- Trial name
- PEERS (NCT06182033)
- Testing
- Peer-mediated pivotal response training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Stroke, Aphasia
Digital Interventions in Neurorehabilitation: iTALKbetter
iTALKBetter will provide an app-based therapy for people with word retrieval difficulties who have had a stroke. This study aims to test the therapy application for people with naming difficulties through a small scale…
- Conditions
- Stroke, Aphasia, Anomia
- Trial name
- NCT04566081
- Testing
- iTalkBetter Trained Items, iTalkBetter Untrained Items
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- University College, London