Clinical trials: Language Development Disorders
Developmental Language Disorder
Neuroimaging Reveals Treatment-related Changes in DLD
Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes.
- Trial name
- NCT05268341
- Testing
- My Sentence Builder
- Where
- 6 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
DLD
Effect of Phonotactic Probability and Orthography on Vocabulary Learning
The purpose of the study is to investigate how phonotactic probability) and orthography affect vocabulary by children with low oral language levels.
- Trial name
- VOCAB+ (NCT06935851)
- Testing
- VOCAB +
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Developmental Language Disorder and Language Impairment
Recasting or Book Reading by Parents or Clinicians
Developmental Language Disorder (DLD) affects approximately seven percent of the population and is characterized by grammatical deficits that cascade into lifelong academic challenges and under-employment.
- Trial name
- NCT05099328
- Testing
- Recast Therapy, Syntax Stories
- Where
- 2 sites in United States
- Volunteers
- 137 people
- Sponsor
- University of Delaware
Retrocochlear Pathology, Auditory Processing Disorder, Central
Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.
The investigators assume that cochlear implants in this indication are not only effective but also cost-effective. The investigators' experimental protocol relies on real life therapeutic strategy, where a cochlear implant may be…
- Conditions
- Retrocochlear Pathology, Auditory Processing Disorder, Central, Major Cochlear Ossification or Malformation
- Trial name
- CISSD (NCT02204618)
- Testing
- cochlear implantation, 6 months initial abstention
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Toulouse
Dyslexia, Developmental, Language Development Disorders
Language Development Deficits and Early Interactive Music Intervention
Investigators compare effects of 6-month music versus circus group interventions on language development in infants and toddlers with or without familial risk for dyslexia (anticipated total N=200).
- Conditions
- Dyslexia, Developmental, Language Development Disorders, Language Development
- Trial name
- BusyBaby (NCT06261307)
- Testing
- Music intervention, Circus intervention
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Central Auditory Processing Disorder, Hearing Impaired (Partially)
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
The goal of this clinical trial is to determine the efficacy of Clemastine Fumarate in the presence of engineered sound to treat age-related central auditory processing disorder (CAPD).
- Conditions
- Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality
- Trial name
- CAPD-LOOT (NCT07304024)
- Testing
- Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Colorado, Denver
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Language Disorder
Training Caregivers to Teach Vocabulary to Children With Language Impairment
The purpose of this study is to determine whether Spanish-speaking caregivers can learn to teach science vocabulary to their children with the use and educational app and a short training video with target words.
- Trial name
- DLD (NCT07519629)
- Testing
- Robust vocabulary intervention
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Northern Arizona University
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Developmental Language Disorder
Sentence Prediction in Developmental Language Disorder
Millions of children - 7-12% of the school-age population - have developmental language disorder (DLD), a disorder that affects language learning, comprehension, and use.
- Trial name
- NCT07510854
- Testing
- Thematic role, Sentence complexity
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Developmental Language Disorders
Treating Passive Structure Knowledge Deficits in School-Age Children With Developmental Language Disorder
The goal of this project is to compare the relative effectiveness of two novel treatments to improve the knowledge of the passive sentence structure of school-age (8-11-year-old) children with developmental language disorder…
- Trial name
- DLDTreatment (NCT06932016)
- Testing
- Grammar Treatment
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- Ohio University
Child Language, Language Delay
Talk With Me Baby: Leveraging Well-Child Care to Enhance the Early Home Language Environment
Language-rich interactions with a parent or caregiver can serve as a protective factor for young children, by supporting their language development and other positive long-term outcomes, but existing interventions have not had…
- Conditions
- Child Language, Language Delay, Developmental Milestones
- Trial name
- TWMB (NCT07132411)
- Testing
- Patients in Talk With Me Baby Clinics, Patients in Care-As-Usual Clinics
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Kansas Medical Center
Language Development Disorders
Virtual Reality-supported Language Intervention for Preschool Children With DLD
This study aims to test the effectiveness of virtual reality-supported speech therapy in improving basic language skills in children aged 3 to 6 years diagnosed with Developmental Language Disorder (DLD).
- Trial name
- NCT07438639
- Testing
- Virtual Reality Rehabilitation System (VRRS), Taditional Speech Therapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Developmental Language Disorder (DLD)
Evaluating the Effect of Combined Parent Training Plus Speech Therapy on Children With Speech Development Disorder.
Language is an extremely complex cognitive function that, in situations of typical development, i.e. in the absence of deficits or environmental risk, is generally acquired with apparent ease and naturalness (Kuhl, 2010).
- Trial name
- DLD25!! (NCT07426276)
- Testing
- Assisted speech therapy intervention + parent training, standard speech therapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Development Language Disorder
Promoting Motivation and Linguage in Developmental Language Disorder Through Interaction With the Humanoid Social Robot
Developmental Language Disorder (DLD) is a communication disorder that interferes with learning, understanding, and using language.
- Trial name
- NCT07426328
- Testing
- Nao assisted therapy, Standard therapeutic protocol
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Development Delay, Child Development
Psychological Correlates of Developmental Delays in Preschool Children
The goal of this observational study is to investigate perinatal, cognitive, linguistic and social-emotional correlates of developmental delays of preschool children.
- Conditions
- Development Delay, Child Development, Social Functioning, Speech Delay
- Trial name
- NCT07420829
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Developmental Language Disorder and Language Impairment
Efficacy of Let's Know! First Grade
Oral language skills are vital for reading comprehension. Some children, however, are at increased risk for reading comprehension difficulties due to underlying oral language deficits.
- Trial name
- NCT06945289
- Testing
- Let's Know!
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Central Auditory Processing Disorder, Autism Spectrum Disorder
Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder
The proposed study aims to understand poor sleep as a possible cause to CAPD in children and adolescents with ASD (ASD+) compared to ASD youth without CAPD (ASD-), using both caregiver-report and objective clinician administered…
- Conditions
- Central Auditory Processing Disorder, Autism Spectrum Disorder, Sleep Disturbance
- Trial name
- ASD (NCT06059352)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Loma Linda University
Language Development Disorders
EMT en Español for Spanish-speaking Toddlers With Language Delays
The goal of the study is to conduct an initial efficacy study of a promising therapist and caregiver-implemented communication intervention to improve language and school readiness skills in low-income Spanish-speaking children…
- Trial name
- NCT04066049
- Testing
- EMT en Español
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction
Neurobehavioral Development in Toddlers and Preschoolers in Relation to Prenatal Exposure of Mild Analgesics (NeuroToP - a COPANA Follow up)
Fundamental aspects of both neurological and reproductive function are established in fetal life, and there is a present increased awareness of the potential effects of fetal exposures on neurodevelopmental and reproductive…
- Conditions
- Gonad Regulating Hormone Adverse Reaction, Analgesic Adverse Reaction, Developmental Disability, Adhd
- Trial name
- NeuroToP (NCT07316387)
- Where
- Denmark
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet