Clinical trials: Laparoscopic, open to volunteers
RCC, Renal Cell Cancer, Partial Nephrectomy
Prospective Study on the Safety and Efficacy of Robot-Assisted Laparoscopic Partial Nephrectomy With Renal Artery Off-Clamp in the Treatment of cT1 Renal Tumors
Renal tumors are common urological cancers, with over 430,000 new cases and more than 170,000 deaths globally in 2020. In China, renal cancer ranks third among urological malignancies, with an increasing incidence.
- Trial name
- NCT06908902
- Testing
- partial nephrectomy with main or branch renal artery clamping, partial nephrectomy with zero renal artery clamping
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Pudendal Neuralgia, Neuralgia
Perioperative Medical Program to Optimize Nerve Regeneration After Robot-assisted Laparoscopic Neurolyses of Pudendal and/or Inferior Cluneal Nerves for Chronic Neuralgias: Results After 1-year Follow-up
Pudendal and inferior cluneal neuralgias are responsible for chronic pelvicperineal pain. These two neuralgias are associated in approximately 25% of cases.
- Trial name
- REGEN (NCT06796595)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- UBOSGA
Gastrostomy
EOI Block for Laparoscopic Gastrostomy
This randomized controlled trial will evaluate the efficacy of ultrasound-guided external oblique intercostal fascial plane (EOI) block in reducing intraoperative and postoperative pain in pediatric patients undergoing…
- Trial name
- NCT07119346
- Testing
- EOI block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Appendicitis Acute, Appendicitis Perforated
Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days…
- Conditions
- Appendicitis Acute, Appendicitis Perforated, Appendicitis With Perforation, Appendicitis Suppurative
- Trial name
- NCT06948071
- Testing
- Discharge on oral antibiotics
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Prostate Cancer, Anesthesia
Low-flow Versus Minimal-flow Sevoflurane Anesthesia During Robot-assisted Laparoscopic Radical Prostatectomy
Study Synopsis This protocol is formatted for ClinicalTrials.gov-style registration and manuscript-facing documentation. It is based on the uploaded Turkish ethics protocol and keeps the original core design: comparison of…
- Conditions
- Prostate Cancer, Anesthesia, Respiratory Mechanics
- Trial name
- NCT07475533
- Testing
- Common Anesthetic Management
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Colorectal Neoplasms, Incisional Hernia
AP-NOSES: A Prospective Multicentre Registry of Natural Orifice Specimen Extraction in Minimally Invasive Colorectal Surgery
Natural orifice specimen extraction (NOSE) is a minimally invasive colorectal surgical technique in which the surgical specimen is removed through a natural orifice, including transanal or transvaginal routes, thereby avoiding an…
- Trial name
- AP-NOSES (NCT07615036)
- Testing
- Natural Orifice Specimen Extraction, Transabdominal Specimen Extraction
- Where
- Singapore
- Volunteers
- 800 people
- Sponsor
- Singapore General Hospital
Diverticular Diseases, Diverticulitis
RObotic Versus LAparoscopic Colectomy for DIverticulitis.
Over the last decade there has been a growing interest toward the application of robotic approach for diverticular disease. The evidence available on the literature showed that robotic approach, compared to the laparoscopic…
- Trial name
- ROLADI (NCT05829343)
- Testing
- Laparoscopic Left colectomy, Robotic left colectomy
- Where
- Italy
- Volunteers
- 1,450 people
- Sponsor
- S.M. Misericordia Hospital
Laparoscopic, Inguinal Hernia
Mesh Fixation Versus Non Fixation in Laparoscopic Inguinal Hernioplasty
Inguinal hernia is one of the most common types of abdominal hernias. Laparoscopic hernioplasty of inguinal hernia is a good alternative to traditional open repairs even in simple unilateral primary inguinal hernia in terms of…
- Conditions
- Laparoscopic, Inguinal Hernia, Hernioplasty
- Trial name
- NCT06258317
- Testing
- fixation of conventional polypropylene mesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ectopic Pregnancy
Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy
This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.
- Trial name
- vNOTES (NCT07057115)
- Testing
- vNOTES Salpingectomy Group., Laparoscopic Salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Laparoscopic Hysterectomy
Effect of Trendelenburg Position on Patient State Index
The goal of this observational study is to evaluate whether the Trendelenburg position affects electroencephalography-based depth of anesthesia monitoring and cerebral oxygenation during general anesthesia.
- Trial name
- NCT07467200
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Laparoscopic Hysterectomy
Oxycodone Versus Sufentanil in Patient-controlled Intravenous Analgesia After Laparoscopic Hysterectomy
This study is designed to evaluate the efficacy and safety of hydrocodone in patient-controlled intravenous analgesia (PCIA) during gynecological laparoscopy, thus to explore suitable PCIA scheme to optimize postoperative pain…
- Trial name
- Oxycodone (NCT06690307)
- Testing
- patient controlled intravenous analgesia(PCIA)
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Affiliated Hospital of Nantong University
Surgery, Laparoscopic
Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain
This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery.
- Conditions
- Surgery, Laparoscopic, Laparoscopy, Penumoperitoneum
- Trial name
- NCT06504277
- Testing
- Low Pressure Penumoperitoneum, Standard Pressure Group (No intervention- active comparator)
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
ERAS
Impact of ERAS Protocol on Length of Hospital Stay After Laparoscopic Surgeries
The goal of this clinical trial is to determine the length of hospital stay in patients using multimodal analgesia with or without ERAS protocol scheduled for elective laparoscopic gynecological surgeries
- Trial name
- NCT07116564
- Testing
- Enhanced Recovery After Surgery, Control
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Aga Khan University
Hypertension, Retroperitoneal Disease
Clinical Analysis of the Antihypertensive Effect of Laparoscopic Peripheral Nerve Blockade of the Renal Artery in Patients With Retroperitoneal Disease and Hypertension
The primary objective of this study is to evaluate the efficacy and safety of laparoscopic renal artery nerve blockade surgery in patients with retroperitoneal diseases complicated by hypertension.
- Trial name
- NCT06829134
- Testing
- laparoscopic renal artery perivascular nerve blockade, surgery related to the primary disease
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Ruijin Hospital
PCV-VG Versus VCV Ventilation Mode Effects on Hemodynamics
Effect of Pressure-Controlled Volume Guaranteed Versus Volume-Controlled Ventilation Modes on Hemodynamic Outcomes e.g ( SV, CO ) and Respiratory Mechanics During Laparoscopic Abdominal Cancer Surgeries With Exaggerated Trendelenberg Postion
The primary outcome is to compare the hemodynamic outcomes ( e.g SV , CO and CI ) using The ICON of two different modes of ventilation ( VCV and PC-VG ) during laparoscopic abdominal cancer surgeries with exaggerated…
- Trial name
- NCT07550738
- Testing
- electrical cardiometry ('ICON CARDIOTRONIC, OSYPKA MEDICAL') , Lung ultrasonography (LUS) for atelectasis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Inguinal Hernia, Pediatrics
A Comparison Between Two Laparoscopic Techniques in Management of Inguinal Hernias in Pediatrics
To compare between the use of the percutaneous internal ring suturing (PIRS) technique and the Laparoscopic intraperitoneal purse-string suture sac closure technique.
- Trial name
- Pediatrics (NCT06975826)
- Testing
- Laparscopic percutaneous internal ring suturing (PIRS) technique in Management of inguinal hernia, Laparscopic inguinal herniotomy in pediatrics
- Volunteers
- 50 people
- Sponsor
- Assiut University
Oxygenation Index
Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia
This was a multicenter, prospective, parallel-grouping, randomized controlled clinical study comparing low FiO2 (40%) and high FiO2 (80%) levels in older patients undergoing laparoscopic gastrointestinal surgery.
- Trial name
- NCT06359106
- Testing
- 80% Oxygen, 40% Oxygen
- Where
- 16 sites in China
- Volunteers
- 1,176 people
- Sponsor
- China Medical University, China
Postoperative Pain, Laparoscopic Cholecystectomy
External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy
This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy, Paravertebral Block, External Oblique Intercostal Plane Block
- Trial name
- NCT07241949
- Testing
- Paravertebral Block (PVB), External Oblique Intercostal Block (EOI Block), Tramadol IV Patient-Controlled Analgesia (PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Cukurova University
Laparoscopic Cholecystectomy
Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery
The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability…
- Trial name
- NCT07488078
- Testing
- Lactated Ringer 500ml, Lactated Ringer 1000ml
- Where
- Pakistan
- Volunteers
- 380 people
- Sponsor
- King Edward Medical University
Cholecystectomy, Laparoscopic, Anesthesia
Deep Rectus Sheath Block for Laparoscopic Cholecystectomy
Postoperative pain after laparoscopic cholecystectomy can be considerable. Regional techniques such as erector spinae plane (ESP) block or transversus abdominis plane (TAP) block may be suitable for patients at increased risk of…
- Conditions
- Cholecystectomy, Laparoscopic, Anesthesia, Postoperative Pain
- Trial name
- NCT06976320
- Testing
- Intravenous morphine patient control analgesia, Intravenous patient control analgesia, Deep rectus sheath block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University