Clinical trials: Laparoscopic
Dexmedetomidine, Total Intravenous Anesthesia
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies.
- Conditions
- Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
- Trial name
- DEXREM (NCT06684197)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Analgesic Efficacy, Dexmedetomidine
Analgesic Efficacy of Adding Dexmedetomidine to Erector Spinae Plane Block Versus Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy
Our scientific work aimed to evaluate the analgesic efficacy of dexmedetomidine as an adjuvant to erector spinae plane block versus subcostal transverse abdominis plane block in patients undergoing laparoscopic cholecystectomy.
- Conditions
- Analgesic Efficacy, Dexmedetomidine, Erector Spinae Plane Block, Subcostal Transverse Abdominis Plane Block
- Trial name
- NCT07075913
- Testing
- Subcostal transverse abdominis plane block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Kafrelsheikh University
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07525986
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- 4 sites in China
- Volunteers
- 140 people
- Sponsor
- Peking University First Hospital
Early Gastric Cancer, Adenocarcinoma of the Stomach
SPADE Clinical Trial.
Purpose: This multicenter, prospective, single-arm phase 2 clinical trial aims to evaluate the safety, feasibility, and clinical outcomes of the SPADE operation (Spade-Shaped Anastomosis) in patients undergoing laparoscopic or…
- Conditions
- Early Gastric Cancer, Adenocarcinoma of the Stomach, Proximal Gastric Cancer, SPADE Operation
- Trial name
- SPADE (NCT07892183)
- Testing
- Spade-Shaped Anastomosis after Laparoscopic or Robotic Proximal Gastrectomy Using Double Suture Anchoring between the Posterior Wall of the Esophagus and the Anterior Wall of the Stomac
- Where
- South Korea
- Volunteers
- 159 people
- Sponsor
- National Cancer Center, Korea
Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring
Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring
The aim of this study is to evaluate the effects of processed electroencephalogram (pEEG) monitoring on recovery and extubation times, length of stay in the post-anesthesia care unit (PACU), postoperative pain, patient comfort…
- Trial name
- TandRT (NCT07670689)
- Testing
- Bispectral index monitoring
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Cukurova University
Laparoscopic Cholecystectomy
Binaural Beats and Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy
This research is a single-center, parallel-group, single-blind, randomized controlled experimental study planned to evaluate the effect of postoperative binaural beats (BB) application on the incidence of postoperative nausea and…
- Trial name
- NCT07879274
- Testing
- Binaural Beats Application
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Bitlis Eren University
Laparoscopic Cholecystectomy Surgery
Effects of the 4-7-8 Breathing Technique on Postoperative Pain Scores, Anxiety, and Sleep Quality in Patients
This study aims to evaluate the effects of teaching the 4-7-8 breathing technique, one of the deep breathing techniques, to patients undergoing laparoscopic cholecystectomy surgery and applying it during the preoperative and…
- Trial name
- NCT07303634
- Testing
- 4-7-8 Breathing Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Postoperative Pain, Cholecystectomy
Comparison of M-TAPA, EOIP, and Local Infiltration for Pain Relief After Laparoscopic Cholecystectomy
This retrospective observational study aimed to compare three pain management techniques used after laparoscopic gallbladder removal (cholecystectomy): modified thoracoabdominal nerve block through the perichondrial approach…
- Conditions
- Postoperative Pain, Cholecystectomy, Laparoscopic, External Oblique Intercostal Plane Block
- Trial name
- NCT07881536
- Testing
- Modified Thoracoabdominal Nerve Block Through the Perichondrial Approach, External Oblique Intercostal Plane Block, Local anesthetic infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Pamukkale University
Intravenous Lidocaine, Laparoscopic Surgery
Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery
This randomized controlled trial evaluates whether perioperative intravenous lidocaine infusion, combined with port-site ropivacaine infiltration, improves postoperative recovery after laparoscopic abdominal surgery.
- Conditions
- Intravenous Lidocaine, Laparoscopic Surgery, Post Operative Recovery, Local Anaesthetic Systemic Toxicity
- Trial name
- LivQor (NCT07414706)
- Testing
- Procedure/Standard care, ropivacaine, Lidocaine (intravenous infusion, perioperative)
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Postoperative Pain, Cholecystectomy, Laparoscopic
Recto-Intercostal Fascial Plane and External Oblique Intercostal Blocks for Pain in Laparoscopic Cholecystectomyin Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a common surgical procedure that can cause significant postoperative pain, particularly originating from trocar insertion sites.
- Trial name
- NCT07777172
- Testing
- Group EOIPB (External Oblique Intercostal Plane Block), Group EOIPB + RIFPB (Combined Blocks)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Laparoscopic Cholecystectomy, Postoperative Pain
Subcostal TAP Block Versus Combined Subcostal TAP and Recto-Intercostal Fascial Plane Block for Analgesia After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is commonly associated with moderate postoperative pain, particularly during the early postoperative period.
- Trial name
- NCT07869316
- Testing
- Subcostal Transversus Abdominis Plane Block, Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Appendectomy, Laparoscopic, Acute Appendicitis
Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children. Despite the widespread adoption of laparoscopic appendectomy, postoperative care still varies widely between institutions, with prolonged fasting, opioid-based…
- Conditions
- Appendectomy, Laparoscopic, Acute Appendicitis, Pediatric Surgery, ERAS
- Trial name
- NCT07643285
- Testing
- Comprehensive 20-Item Pediatric ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahmet Burak Doğan, MD
Postoperative Pain, Laparoscopic Cholecystectomy Surgery
Impact of Video-Based Patient Education on Physician Trust, Pain, and Anxiety in Laparoscopic Cholecystectomy
This prospective, randomized, single-center, single-blind study aims to evaluate the effects of video-based preoperative education on physician trust, postoperative pain, anxiety, and opioid consumption in patients undergoing…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy Surgery, Preoperative Anxiety, Trust in Healthcare System
- Trial name
- VITAP (NCT07767344)
- Testing
- Video-Based Preoperative Block Education, Standard Verbal Preoperative Block Education
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Sanliurfa Education and Research Hospital
Cholecystectomy, Laparoscopic
Prophylactic Antibiotic in Non-complicated Low Risk Lap Cholecystectomy (LC)
To Compare between outcomes of Antibiotic prophylaxis and no antibiotic prophylaxis in low risk non-complicated laparoscopic cholecystectomy
- Trial name
- NCT06193837
- Testing
- Cefazoline
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Inflammatory Response, Perioperative Hypothermia
Effects of Intraoperative Warming Methods on Hematologic Inflammatory Indices in Laparoscopic Cholecystectomy
Perioperative hypothermia is a frequent and preventable complication that may cause adverse outcomes such as increased blood loss, impaired coagulation, and delayed recovery.
- Conditions
- Inflammatory Response, Perioperative Hypothermia, Laparoscopic Cholecystectomy, Surgical Stress Response
- Trial name
- WARM-CHOL (NCT07232251)
- Testing
- Standard Active Warming Blanket, Intravenous Warmer Group, External Warmer Group
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ataturk University
Laparoscopic, Extended View
Laparoscopic Extended View Totally Extra Peritoneal (e.TEP) in Comparison to Traditional TEP Technique for Inguinal Hernia Repair
The aim of this prospective randomized clinical study is to compare effectiveness, feasibility and outcome between total extra peritoneal (TEP) and extended TEP (E-TEP) techniques in repair of inguinal hernia.
- Conditions
- Laparoscopic, Extended View, Totally Extra Peritoneal, Inguinal Hernia Repair
- Trial name
- NCT07872410
- Testing
- Totally extra peritoneal, Extended view totally extra peritoneal
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Mansoura University
Laparoscopic Cholecystectomy
The Effect of White Noise on Sleep, Quality of Recovery, and Satisfaction in Patients Undergoing Laparoscopic Cholecystectomy
This randomized controlled trial aims to evaluate the effect of white noise on sleep, recovery quality, and satisfaction in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07867613
- Testing
- White Noise
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Appendicitis Perforated, Appendectomy, Laparoscopic
Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis
The ALPACA-MC trial is a blinded, multicentre randomized controlled trial comparing two postoperative antibiotic treatments for children undergoing laparoscopic appendectomy for perforated appendicitis.
- Conditions
- Appendicitis Perforated, Appendectomy, Laparoscopic, Antibiotic, Pediatric
- Trial name
- ALPACA-MC (NCT07869095)
- Testing
- Piperacillin/Tazobactam, Ceftriaxone + Metronidazole
- Volunteers
- 180 people
- Sponsor
- McMaster Children's Hospital
Laparoscopic Cholecystectomy
The Effect of Guided Imagery in Laparoscopic Cholecystectomy
This clinical trial examines the effects of guided imagery in adults recovering from laparoscopic gallbladder surgery. The study focuses on pain levels, vital signs, and the quality of recovery after surgery.
- Trial name
- NCT07860385
- Testing
- Guided Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people
- Sponsor
- Malatya Turgut Ozal University
Transversus Abdominis Plane Block (TAP Block), Laparoscopic Inguinal Hernia Repair
Spinal Anesthesia Versus General Anesthesia Plus TAP Block for Laparoscopic Inguinal Hernia Repair
This prospective, randomized, double-blind clinical trial compares spinal anesthesia with general anesthesia combined with ultrasound-guided transversus abdominis plane (TAP) block in adult patients undergoing laparoscopic total…
- Trial name
- NCT07866885
- Testing
- General Anesthesia Plus Transversus Abdominis Plane Block, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Fatma Cigdem Ozakin