Clinical trials: Laparoscopic, open to volunteers
Hernia
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
The primary purpose of this clinical trial is to assess the safety and performance of the ECLIPSIUM device in securing mesh during ventral hernia repair.
- Trial name
- UNITE (NCT07277946)
- Testing
- ECLIPSIUM® System, Resorbable tacks (AbsorbaTack/SorbaFix)
- Where
- 12 sites in United States
- Volunteers
- 240 people
- Sponsor
- Tissium
Postoperative Pain
US Guided EOI Block Versus ESPB for Postoperative Analgesia in Laparoscopic Cholecystectomy
To compare the efficacy of USG-guided bilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both External…
- Trial name
- NCT05272280
- Testing
- External oblique intercostal (EOI) block, Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Patients Undergoing Laparoscopic Surgery
Quantitative Analysis of EEG Changes in Response to Nociception
This study will quantify the nociception using Analgesia Nociception Index (ANI) during general anesthesia and analyze the differences in EEG depending on the degree of nociception.
- Trial name
- NCT06342570
- Testing
- There is no Intervention name to describe.
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Gangnam Severance Hospital
Recurrant Inguinal Hernia
Outcomes of Laparoscopic Keyhole Surgery (TAPP) for Recurrent Inguinal Hernia
The goal of this clinical trial is to learn if a laparoscopic surgery called Transabdominal Preperitoneal (TAPP) repair is safe and works well for adults with a recurrent inguinal hernia (a groin hernia that has returned after a…
- Trial name
- NCT07608653
- Testing
- Laparoscopic Transabdominal Preperitoneal (TAPP) Repair
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sohag University
Endometrial Cancer, Near Infrared Fluorescence Imaging
CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer
The research study is being done to assess the safety and ability of an investigational drug called CYTALUX (pafolacianine) and a special camera system for the detection of cancer in patients undergoing surgical resection for…
- Conditions
- Endometrial Cancer, Near Infrared Fluorescence Imaging, CYTALUX (Pafolacianine) Injection, Planned Diagnostic Laparoscopies
- Trial name
- CYTALUX ISS (NCT07278986)
- Testing
- CYTALUX™ (pafolacianine), 1788 4K Camera System with Advanced Imaging Modality
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Gastric Cancer
Prophylactic Preoperative HIPEC in Advanced Gastric Cancer at High Risk of Peritoneal Recurrence
The study was designed to evaluate the efficacy of perioperative FLOT chemotherapy in combination with perioperative hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with advanced gastric cancer at high risk of…
- Trial name
- CHIMERA (NCT04597294)
- Testing
- FLOT + HIPEC + Surgery, FLOT + Surgery
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Jagiellonian University
Postoperative Pain, Acute
Comparison of Transversus Abdominis Plane and Erector Spinae Plane Blocks for Pain Control After Renal Laparoscopy
The goal of this study is to compare the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block versus erector spinae plane block (ESPB) in adult patients undergoing laparoscopic renal surgeries.
- Trial name
- TAP-ESPB (NCT07781930)
- Testing
- TAP Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Gastrostomy Complications, Gastrostomy Size
Does the Thickness of the Gastrostomy Affect the Incidence of Complications? A Prospective Randomized Single-Center Study in Children
The goal of this interventional study is to compare two different sizes of a gastrostomy tube in children and the incidence of complications three months postoperatively.
- Conditions
- Gastrostomy Complications, Gastrostomy Size, Food Intolerance, Granuloma
- Trial name
- NCT07300865
- Testing
- 12 Fr gastrostomy tube/button, 14 Fr gastrostomy tube/button
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Therese Hössjer
Gastric Cancer, Surgery
3D-4K-ICG Laparoscopic Gastrectomy for Gastric Cancer
Patients with locally advanced gastric adenocarcinoma (CT2-4a N-/+ M0) were selected as study subjects to investigate the safety, efficacy, and feasibility of ICG near-infrared imaging tracing in 3D plus ultra high resolution…
- Trial name
- 3D-4K-ICG (NCT06161207)
- Testing
- Indocyanine Green Tracer Using in 3D plus Ultra High Resolution Laparoscopic Gastrectomy with Lymph Node Dissection
- Where
- China
- Volunteers
- 702 people
- Sponsor
- Fujian Medical University
Anesthesia, Anesthesia and Procedure Related Time Intervals
Multimodal Anesthesia in Robotic Laparoscopic Nephrectomy
It is a prospective, randomized, controlled and superiority clinical trial, with the objective of comparing the effectiveness of multimodal anesthesia versus conventional anesthesia in patients undergoing oncological robotic…
- Conditions
- Anesthesia, Anesthesia and Procedure Related Time Intervals, Nephrectomy / Methods
- Trial name
- MANTRA (NCT07558226)
- Testing
- Multimodal anesthesia, Conventional anesthesia
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundacio Puigvert
Post Operative Pain
A Comparison Between The Efficacy of Modified Thoracoabdominal Plane Block Via Perichondral Approach (M-TAPA) And External Oblique Intercostal Plane Block (EOIPB) in Patients Undergoing Laparoscopic Cholecystectomy Surgeries (LC)
Because laparoscopic procedures have a number of benefits over open procedures, they have completely changed the surgical industry.(1) Laparoscopic cholecystectomy (LC) is a minimally invasive technique that usually yields less…
- Trial name
- NCT06810206
- Testing
- Bilateral Ultrasound Guidance M-TAPA, Bilateral Ultrasound Guidance EOIPB
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Adrenal Tumor, Adrenalectomy; Status
3D Laparoscopic Adrenalectomies for Adrenal Tumors
The main drawbacks of conventional 2D laparoscopy are limited depth perception and loss of spatial orientation. High-quality 3D laparoscopy systems might improve surgical outcomes for adrenalectomy.
- Trial name
- NCT04905706
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Pancreatic Cancer, Common Bile Duct Diseases
A Multicenter Prospective Randomized Controlled Study of RPD Versus LPD
laparoscopic pancreaticoduodenectomy(LPD) and Robot Pancreaticoduodenectomy (RPD), as two minimally invasive methods of pancreaticoduodenectomy(PD), have obvious advantages over traditional open pancreaticoduodenectomy(OPD) in…
- Conditions
- Pancreatic Cancer, Common Bile Duct Diseases, Periampullary Carcinoma
- Trial name
- NCT05755607
- Testing
- laparoscopic pancreaticoduodenectomy, Robot Pancreaticoduodenectomy
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of University of South China
Laparoscopic, Inguinal Hernia
Mesh Fixation Versus Non Fixation in Laparoscopic Inguinal Hernioplasty
Inguinal hernia is one of the most common types of abdominal hernias. Laparoscopic hernioplasty of inguinal hernia is a good alternative to traditional open repairs even in simple unilateral primary inguinal hernia in terms of…
- Conditions
- Laparoscopic, Inguinal Hernia, Hernioplasty
- Trial name
- NCT06258317
- Testing
- fixation of conventional polypropylene mesh
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Colorectal Surgery, Benign or Malignant Rectal or Colon Tumors
Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY)
The objective of this prospective, international cohort is to incorporate the low stable pressure (using Airseal Insufflator) approach and its associated parameters into the early rehabilitation program after colorectal surgery…
- Trial name
- CROSS (NCT06154785)
- Where
- 18 sites in Belgium, France and 6 more
- Volunteers
- 300 people
- Sponsor
- Bordeaux Colorectal Institute Academy
Pain Management, Laparascopic Sleeve Gastrectomy
Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery
Shoulder pain is a well-recognized complaint following laparoscopic surgery. It is underlying mechanism has various causes, therefore, modalities in management and prevention of this sort of pain are numerous with different…
- Trial name
- NCT07429916
- Testing
- Intraoperative ketamine
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- King Abdullah University Hospital
Retrolaminar Block, TAP Block
Ultrasound Guided Retrolaminar Block Versus Transverse Abdominis Plane Block in Laparoscopic Upper Abdominal Surgeries
This study aims to compare and evaluate the safety and efficacy of ultrasound guided retrolaminar block versus transverse abdominis plane block in laparoscopic upper abdominal surgeries.
- Conditions
- Retrolaminar Block, TAP Block, Laparoscopic Abdominal Surgeries
- Trial name
- NCT07720817
- Testing
- Ultrasound-guided Retrolaminar Block group, Transverses Abdominis Plane (TAP) Block Group
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Colon Cancer
Mechanical Bowel Preparation in Laparoscopic Right Hemicolectomy With Intracorporeal Anastomosis
This study is a randomized controlled trial conducted at University Medical Center Ho Chi Minh City to evaluate the role of mechanical bowel preparation (MBP) in patients undergoing laparoscopic right hemicolectomy with totally…
- Trial name
- UMC-Colprep (NCT07546565)
- Testing
- Mechanical Bowel Preparation, No mechanical bowel preparation
- Where
- Vietnam
- Volunteers
- 74 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Laparoscopic Adnexal Surgery
Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery
We hypothesize that instilling intraperitoneal Marcaine (without epinephrine) at the end of a non-total laparoscopic gynecologic surgery (adnexa only, which includes the ovaries, fallopian tubes, and associated ligaments…
- Trial name
- NCT06842771
- Testing
- Normal Saline (0.9% NaCl), Marcaine hydrochloride without epinephrine 0.5%
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Tennessee
Cirrhosis, Splenectomy
Efficacy of Apixaban in Treating Portal Vein Thrombosis Occurring More Than One Year After LSD
The purpose of this study is to determine whether Apixaban is effective and safe in the treatment of portal vein thrombosis Occurring more than one year after laparoscopic splenectomy and azygoportal disconnection.
- Conditions
- Cirrhosis, Splenectomy, Portal Vein Thrombosis, Hypertension, Portal
- Trial name
- NCT07461532
- Testing
- Apixaban 2.5 MG
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Northern Jiangsu People's Hospital