Clinical trials: Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy
Responses to Colloid Infusions
In situations such as dehydration, illness and surgery, fluid 'drips' are given to patients to keep them hydrated. Different fluids stay in the circulation for different lengths of time.
- Trial name
- NCT00868062
- Testing
- Succinylated gelatine, 40g/L, (Gelofusine - B Braun)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Postoperative Pain
Compare Intraperitoneal Instillation of Bupivacaine+dexmedetomidine Versus Bupivacaine+dexamethasone on Postoperative Pain After Lap Cholecystectomy
Comparison of intraperitoneal instillation of bupivacaine with dexmedetomidine versus bupivacaine with dexamethasone on postoperative pain after laparoscopic cholecystectomy
- Trial name
- NCT06535256
- Testing
- bupivacaine with dexamethasone, bupivacaine with dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Pain, Postoperative
Clinical Trial of the Use of Intraperitoneal Local Anaesthetic
Patients undergoing keyhole gall bladder removal will be divided into 3 groups, one control, one will have local anaesthetic and the third will have normal saline nebulised into their abdomen before closure of the wounds to…
- Trial name
- NCT00180687
- Testing
- Nebulised Bupivacaine intraperitoneally, Normal Saline, Injected Bupivacaine intraperitoneally
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Idiopathic Acute Pancreatitis
Preventing Recurrent 'Idiopathic' Acute Pancreatitis Through Laparoscopic Cholecystectomy (PICUS-2)
Rationale: Annually, acute pancreatitis is diagnosed in 6,500 patients in the Netherlands. In up to 25% of patients no definitive cause can be determined after routine work-up including endoscopic ultrasound and this is deemed to…
- Trial name
- PICUS-2 (NCT06391359)
- Testing
- Laparoscopic cholecystectomy, Watchful waiting
- Where
- Netherlands
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- M.G. Besselink
Post Operative Pain, Opioid Side Effects
Find the Adequate Dose of Nalbuphine for Laparoscopic Cholecystectomy
This study evaluate the adequate dose of mutonpain for laparoscopic cholecystectomy in the management of post operative pain. The investigators will randomize patients into three groups to compare the analgesia effects and side…
- Trial name
- NCT04135534
- Testing
- group A, group B, group C
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Laparoscopic Cholecystectomy, Post Operative Analgesia
Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy
This study aims to compare the level of postoperative pain experienced by patients undergoing laparoscopic cholecystectomy with and without the use of intraperitoneal bupivacaine.
- Conditions
- Laparoscopic Cholecystectomy, Post Operative Analgesia, Bupivacaine
- Trial name
- BUPA-LC (NCT07098429)
- Testing
- Bupivacain (Postoperative), Normal (0.9%) saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Physiological Effects of Drugs
Immunomodulatory Effect of Dexmedetomidine as an Adjuvant Drug in Laparoscopic Cholecystectomies
Trauma triggers a tissue response involving the central nervous system, the hypothalamic-pituitary-adrenal axis and the immune system.
- Trial name
- NCT05489900
- Testing
- Dexmedetomidine Hydrochloride
- Where
- Brazil
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Acute Cholecystitis
Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study
The best management of the acute cholecystitis is to do laparoscopic cholecystectomy. The hypothesis is that to do it as an early intervention after patient admission is better than delayed cholecystectomy regarding the hospital…
- Trial name
- NCT02130245
- Testing
- Early cholecystectomy, Delayed cholecystectomy
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Postoperative Analgesia
Comparison of Postoperative Analgesia in Erector Spinae Plane Block (ESPB) v/s Subcostal Transversus Abdominal Plane Block (STAP) in Adults Undergoing Laparoscopic Cholecystectomy.
Postoperative pain after laparoscopic cholecystectomy remains clinically relevant. This double-blinded randomized controlled trial compares the analgesic efficacy of landmark-guided Erector Spinae Plane Block (ESPB) and subcostal…
- Trial name
- NCT07469410
- Testing
- Landmark guided Erector Spinae Block, Landmark guided Transversus Abdominis Plane Block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Patel Hospital, Pakistan
Muscle Relaxation
Deep vs Moderate Neuromuscular Blockade in Day Case Laparoscopic Cholecystectomy.
Laparoscopic cholecystectomy (LC) is commonly performed on ambulatory basis as a result of its ability to improve postoperative quality of recovery (QOR) and significantly reduce hospital stay .
- Trial name
- NCT03881423
- Testing
- Rocuronium Bromide
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Pain, Postoperative
Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is associated with considerable postoperative pain and surgeon-administered local anesthetic infiltration is the standard practice for achieving post-operative analgesia.
- Trial name
- NCT02712151
- Testing
- Abdominal Wall Block, Surgical infiltration, Sterile saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Laparoscopic Cholecystectomy
Comparison Between Dexmedetomidine and Fentanyl As an Adjuvant to Bupivacaine in the Paravertebral Nerve Block in Laparoscopic Cholecystectomy for Postoperative Analgesia: Randomized Comparative Clinical Trial.
Laparoscopic cholecystectomy is one of the most common surgeries today, cause it has many advantages over open cholecystectomy. Although these advantages pain remains a big problem after laparoscopic cholecystectomy which causes…
- Trial name
- NCT06752629
- Testing
- Bupivacaine and Dexmedetomidine, Bupivacaine and Fentanyl
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Consent, Laparoscopic
Optimizing the Consent Process for Emergent Laparoscopic Cholecystectomy
The Canadian Medical Protective Association (CMPA) defines informed consent (IC) as a voluntary process where important elements include details of the procedure, complications, and proposed alternatives.
- Conditions
- Consent, Laparoscopic, Cholecystectomy
- Trial name
- NCT04852016
- Testing
- Consent process with the addition of Digital educational platform (DEP), Consent process using the standard verbal consent (SVC)
- Where
- Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Dr. Boris Zevin
Cholecystitis
Video Laryngeal Mask Versus Endotracheal Tube Undergoing Laparoscopic Cholecystectomy Surgery
The aim of this study is to investigate the effectiveness of using a video laryngeal mask for airway management in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT06502028
- Testing
- Video laryngeal mask airway, Endotracheal tube
- Where
- South Korea
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Healthy
Clinical Evaluation of Spring-Type Laparoscopic Clip Technology
The Visu-Loc spring clip is being used to occlude the cystic duct at the time of laparoscopic cholecystectomy. A hepato-iminodiacetic acid (HIDA) scan will be completed on post operative day one to check for biliary leaks.
- Trial name
- NCT00527644
- Testing
- 5mm spring clip
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Postoperative Nausea and Vomiting
Post-operative Nausea Vomiting in Laparoscopic Cholecystectomy
To study the efficacy and side effects of ondansetron with dexamethasone in patients undergoing standard laparoscopic cholecystectomy (control group).
- Trial name
- PONV (NCT02803788)
- Testing
- ramosetron, ondansetron, dexamethasone
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Postoperative Pain
Feasibility Study on Pain Control After Laparoscopic Cholecystectomy
The objective of the study is to hopefully understand the most beneficial way to control pain after removing the gallbladder by keyhole surgery (laparoscopic cholecystectomy).
- Trial name
- NCT03532906
- Testing
- TAP Block, Control
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Cholecystitis
Establishing Visualization Grading Scale on LESS Cholecystectomy
Essential to laparoscopic operations is adequate visualization. Unfortunately there is no grading system to assess the degree or quality of visualization.
- Trial name
- NCT02264444
- Testing
- Cholecystectomy visualization
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida Hospital Tampa Bay Division
Gall Stones
Intraperitoneal Techniques of Local Anaesthesia During Laparoscopic Cholecystectomy
Pain following laparoscopic cholecystectomy (LC) results in morbidity and is a barrier to same day discharge. In several trials local anaesthetic (LA) washed over the liver and gall bladder decreases pain.
- Trial name
- NCT01090882
- Testing
- Bupivocaine, 0.9% normal saline solution
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust