Clinical trials: Laparoscopic Cholecystectomy
Laparocele
Post-Operative Analgesic Effect of Tramadol and Nalbuphine in Smoker and Non-Smoker Patients in LC
This study aims to compare pain severity and analgesic requirements between smokers and nonsmokers following laparoscopic cholecystectomy, evaluating the efficacy of two analgesics, tramadol and nalbuphine.
- Trial name
- NCT07049380
- Testing
- Comparative cross sectional
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Superior University
Cholecystectomy, Laparoscopic
A Randomised Comparison Between Single Incision Laparoscopic Cholecystectomy and Standard Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy has been established as the treatment of choice for symptomatic gallstone disease. The main advantages of laparoscopic surgery are the cosmetic result, reduced postoperative pain, shorter hospital…
- Trial name
- NCT01094379
- Testing
- Standard laparoscopic cholecystectomy, Single incision laparoscopic cholecystectomy
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Athens
Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis
Laparoscopic Cholecystectomy Using Airseal in Children
The goal of this observational study is to compare the use of Airseal versus a standard insufflation, in children who underwent laparoscopic cholecystectomy, between January 2021 and December 2022.
- Conditions
- Gall Stones (& [Calculus - Gall Bladder]), Cholecystitis, Pancreatitis Due to Gallstones, Child, Only
- Trial name
- VBAS (NCT06734507)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Destinval Christelle
Postoperative Pain
Comparison of ESP Block and STAP Plane Block
In order to effectively manage postoperative analgesia in patients planned to undergo elective laparoscopic cholecystectomy, patients will be divided into 2 (two) groups and informed consent forms will be obtained after the…
- Trial name
- NCT06663449
- Testing
- subcostal transversus abdominis plane block, erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Kocaeli University
Preoperative Anxiety, Laparoscopic Cholecystectomy
Humor-Based Video Intervention on Preoperative Anxiety Veya Humor Video and Recovery in Cholecystectomy
This study aims to evaluate whether watching a short humor-based video before surgery can reduce anxiety and negative emotions and increase positive emotions in patients undergoing elective laparoscopic cholecystectomy…
- Trial name
- NCT07861438
- Testing
- Humor-Based Video Intervention, Routine Preoperative Care and Education
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Laparoscopic Cholecystectomy, Choledocholithiasis
Early vs Late Laparoscopic Cholecystectomy After Common Bile Duct Stones Clearance Through Ercp.
There is controversy about timing of cholecystectomy after the common bile duct is cleared of stones. our study aims to compare the results of early vs late cholecystectomy.
- Conditions
- Laparoscopic Cholecystectomy, Choledocholithiasis, ERCP, Bile Duct Injury
- Trial name
- NCT07130864
- Testing
- Early cholecystectomy, Late cholecystectomy
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Khyber Teaching Hospital
Postoperative Pain Management, Laparoscopic Cholecystectomy
Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy
Brief Summary Background: Laparoscopic cholecystectomy is a common procedure where postoperative pain and nausea/vomiting (PONV) remain significant issues, impairing recovery.
- Conditions
- Postoperative Pain Management, Laparoscopic Cholecystectomy, Ondansetron, Postoperative Nausea and Vomiting
- Trial name
- PLUSO (NCT06632184)
- Testing
- Ondansetron Intraperitoneal Lavage, Saline Intraperitoneal Lavage
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Cholecystitis; Gallstone, Mechanical Ventilation Pressure High
The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
In laparoscopic cholecystectomy method, Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards, a decrease in lung's volume and its compliance, an increase in the airway resistance, mismatch between…
- Conditions
- Cholecystitis; Gallstone, Mechanical Ventilation Pressure High, Intraabdominal Hypertension
- Trial name
- NCT04723043
- Testing
- mechanical ventilation modes
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Post Operative Pain
Analgesic Effect of M-TAPA and TAPB on Laparoscopic Cholesistectomy
Cholecystectomy is the most frequently performed abdominal surgery in developed nations, with laparoscopic cholecystectomy being recognized as the gold standard technique for treating gallstones.
- Trial name
- NCT06662617
- Testing
- modified thoracoabdominal nerve block through perichondrial approach, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Cholelithiasis, Cholecystitis
STALL vs Sole Local Wound Infiltration in Laparoscopic Cholecystectomy
This trial is a prospective randomized superiority trial comparing sole ropivacaine based local trocar site infiltration to local infiltration combined with laparoscopic ropivacaine TAP block (STALL) in LCC.
- Conditions
- Cholelithiasis, Cholecystitis, Gallbladder Cancer
- Trial name
- STALL (NCT06123117)
- Testing
- single transversus abdominis laparoscopy-guided plane block, local trocar site ropivacaine infiltration
- Where
- Finland
- Volunteers
- 850 people
- Sponsor
- Helsinki University Central Hospital
Postoperative Pain
The Difference Between the Extrafascial Injection and the Subfascial Injection of Quadratus Lumborum Block
Quadratus lumborum block can be used for the hip surgery and abdominal surgery postoperative analgesia. But the lower thoracic to the hip dermatome can't be blocked at the same time.
- Trial name
- NCT03421821
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Laparocele
Evaluation of Hemodynamic Changes Using Different IAP for LC Under General Anesthesia
This cross-sectional observational study aims to evaluate the hemodynamic changes induced by different intra-abdominal pressures (IAP) during laparoscopic cholecystectomy under general anesthesia.
- Trial name
- NCT07055074
- Testing
- Low Pressure Pneumoperitoneum, Medium Pressure Pneumoperitoneum
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Superior University
Analgesia
Efficacy and Safety of Erector Spinal Plane Block (ESPB) for Analgesia in Laparoscopic Cholecystectomy
Purpose: to evaluate the efficacy and safety of erector spinal block (ESB) for analgesia in laparoscopic cholecystectomy（LC）. Method: This study is a randomized, single-blind, controlled clinical trial.
- Trial name
- NCT04648345
- Testing
- Erector spinal plane block
- Volunteers
- 90 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Cholecystitis, Acute, Cholecystitis; Gangrenous
Risk Factors for Necrotic Cholecystitis During COVID-19 Pandemic.
Gangrenous cholecystitis is the most common complication of acute cholecystitis. Preliminary data showed that COVID-19 patients have a high risk to present necrotic cholecystitis.
- Conditions
- Cholecystitis, Acute, Cholecystitis; Gangrenous, Cholecystitis Suppurative, Covid19
- Trial name
- ChoCO-W (NCT04542512)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poissy-Saint Germain Hospital
Xylitol Gum Chewing, Non-xylitol Gum Chewing
Effect of Xylitol Gum Chewing on Postoperative Bowel Activity
Altogether, 75 patients undergoing elective laparoscopy cholecystectomy were randomly divided into 3 groups (final numbers, xylitol chewing gum: 24 controls, xylitol free chewing gum:25 and control 25 patients).
- Conditions
- Xylitol Gum Chewing, Non-xylitol Gum Chewing, Control Group
- Trial name
- NCT06579339
- Testing
- xylitol chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Giresun University
Cholelithiasis
Multi-Port Versus Single-port Cholecystectomy
The aim of this study is to compare results of the new surgical strategy to the traditional 4-ports technique for cholecystectomy in a randomized controlled trial (RCT).
- Trial name
- MUSIC (NCT01104727)
- Testing
- 4-Ports Cholecystectomy (4PC), Single-Port Cholecystectomy (SPC)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- European Association for Endoscopic Surgery
Laparoscopic Cholecystectomy Surgery Postoperative Analgesia
RLB vs ERSP for Postoperative Analgesia in Lap Cholecystectomy
This prospective, randomized, double-blind clinical trial evaluates the comparative effectiveness of ultrasound-guided retrolaminar block (RLB) and erector spinae plane block (ESPB) for postoperative analgesia in patients…
- Trial name
- NCT07598162
- Testing
- Retrolaminar Block (RLB), Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Acute Cholecystitis
Is it Safe to do Laparoscopic Cholecystectomy for Acute Cholecystitis up to Seven Days?
Objectives: To compare the safety of early (≤72h) versus late (>72h-7days) laparoscopic cholecystectomy (LC) from symptom onset for acute cholecystitis (AC).
- Trial name
- RCT (NCT03999645)
- Testing
- Early laparoscopic cholecystectomy, Late laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour Teaching Hospital
Rescue Analgesia
Comparison of Rescue Analgesia Requirement in Patients Undergoing Laparoscopic Cholecystectomy After Transversus Abdominal Plane (tap) Block Vs Local Anesthetic Wound Infiltration At the End of Surgery
patients undergoing laparoscopic cholecystectomy will be diveided into 2 groups A \& B . Group A will receive local anesthetic wound infiltration and group B will receive Transversus abdominal plane block as a post operative…
- Trial name
- TAP (NCT06803966)
- Testing
- Post Operative Analgesia
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Laparoscopic Cholecystectomy, Postoperative Analgesia
Analgesic Effect of TAP Block After Laparoscopic Cholecystectomy
TAP block is a locoregional analgesic technique that consists of infiltrating a local anesthetic solution between the muscle layers of the abdominal wall. This block produces prolonged parietal analgesia.
- Trial name
- NCT03391531
- Testing
- Bilateral subcostal TAP block
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege