Clinical trials: Laparoscopic Cholecystectomy
Postoperative Nausea and Vomiting
Metoclopramide-Ondansetron vs. Metoclopramide Therapy for Treatment of Nausea and Vomiting Post Laparoscopic Surgery
The incidence of postoperative nausea and vomiting (PONV) after general anesthesia is up to 30% when inhalational anesthetics are used with no prophylaxis.
- Trial name
- NCT03459248
- Testing
- Dual therapy, Monotherapy, General anesthesia
- Where
- Lebanon
- Volunteers
- 120 people
- Sponsor
- Makassed General Hospital
Cholecystitis, Acute, Cholelithiasis
Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
The purpose is to find out if intraoperative acupuncture performed by needling PC 6 and LI4 point bilaterally, and Yin Tang point will help reduce the incidence postoperative nausea and vomiting in patients undergoing…
- Conditions
- Cholecystitis, Acute, Cholelithiasis, Nausea, Postoperative, Vomiting, Postoperative
- Trial name
- NCT05975385
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Baylor College of Medicine
Laparoscopic Cholecystectomy
Unilateral Right-Sided Erector Spinae Plane Block for Analgesia in Laparoscopic Cholecystectomy: Does the Volume Matter? A Randomized Controlled Trial
Laparoscopic cholecystectomy is one of the most common surgeries today, cause it has many advantages over open cholecystectomy. (1) Although these advantages pain remains a big problem after laparoscopic cholecystectomy which…
- Trial name
- NCT07027540
- Testing
- Bupivacaine 0.25% 20ml, 2mg of dexamethasone, 35 ml of Bupivacaine 0.25%
- Volunteers
- 60 people
- Sponsor
- Assiut University
Laparoscopic Cholecystectomy, Cholecystitis; Gallstone
Madany Triangle; a New Era of Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy has an increased incidence of extrahepatic biliary injury or bleeding. The common hepatic duct is on the medial border of the Calot triangle and at risk of injury.
- Trial name
- NCT05951374
- Testing
- Madany triangle
- Where
- Egypt
- Volunteers
- 238 people
- Sponsor
- Aswan University Hospital
Cholecystitis, Pain
Transmuscular Quadratus Lumborum Block for Laparoscopic Cholecystectomy
The TQL block may prove a valuable method for treating postoperative pain following scopic removal of the gall bladder. The trial will compare active TQL block versus placebo TQL block after said operation.
- Trial name
- TQL (NCT02225418)
- Testing
- Ropivacaine, saline
- Where
- Denmark
- Sponsor
- Jens Borglum Neimann
Acute Cholecystitis, Biliary Complications
Acute Cholecystitis Biliary Complications - ICG
Acute cholecystitis is a common indication for emergency laparoscopic cholecystectomy. Inflammatory changes and distorted anatomy may increase the risk of biliary complications, including bile duct injury and bile leak, which are…
- Trial name
- ICG-ACBC (NCT07481760)
- Testing
- ICG
- Where
- Spain
- Volunteers
- 296 people
- Sponsor
- Hospital del Mar
Gall Stone, Gallbladder Inflammation
Benchmarks in Elective Laparoscopic Cholecystectomy
The aim of this observational cohort study is to define peri- and postoperative reference values for elective laparoscopic cholecystectomy, using the achievable benchmarks of care methodology (ABC™).
- Conditions
- Gall Stone, Gallbladder Inflammation, Gall Bladder Pain, Gallstone
- Trial name
- NCT06692517
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 60,000 people
- Sponsor
- Region Östergötland
Bariatric Surgery Candidate, Cholelithiases
Multicenter Cohort of 768 High-risk Patients With Symptomatic Gallstones, Adding Cholecystectomy Did Not Increase Length of Stay or Perioperative Morbidity, Supporting it as a Safe Single-stage Option
Despite numerous single-center reports and meta-analyses, few studies have directly compared outcomes of LSG with versus without concomitant cholecystectomy exclusively in a high-risk cohort as defined above.
- Trial name
- NCT07772440
- Volunteers
- 2,512 people
- Sponsor
- Zagazig University
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Cholecystectomy
This prospective, blinded, randomized clinical trial investigates the effect on postoperative pain and nausea, when performing a ventilator-piloted PRM at the end of a laparoscopic cholecystectomy.
- Trial name
- NCT03026543
- Testing
- Pulmonary Recruitment Maneuver, Laparoscopic cholecystectomy, Ventilator
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Östergötland
Consent, Laparoscopic
Optimizing the Consent Process for Emergent Laparoscopic Cholecystectomy
The Canadian Medical Protective Association (CMPA) defines informed consent (IC) as a voluntary process where important elements include details of the procedure, complications, and proposed alternatives.
- Conditions
- Consent, Laparoscopic, Cholecystectomy
- Trial name
- NCT04852016
- Testing
- Consent process with the addition of Digital educational platform (DEP), Consent process using the standard verbal consent (SVC)
- Where
- Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Dr. Boris Zevin
Laparoscopic Cholecystectomy
Analgesic Effect of Erector Spinea Plane Block Compared to Peritoneal Block in Laparoscopic Cholecystectomy
The aim of this study is to detect weather peritoneal block or erector spinae plane block will provide the most ideal analgesia for patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04064138
- Testing
- Peritoneal block, Ultrasound guided erector spinae plane block, General anesthesia
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Gallstone Disease
Technical Feasibility of Routine Intraoperative Cholangiography During Elective Rigid-hybrid Transvaginal Natural Orifice Transluminal Endoscopic Cholecystectomy
While gold standard in the treatment of symptomatic gall stones is laparoscopic cholecystectomy with instruments introduced through multiple abdominal wall incisions, transvaginal access to the peritoneal cavity offers an…
- Trial name
- NCT01583348
- Testing
- Cholangiography during transvaginal rigid-hybdrid NOTES cholecystectomy
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Cantonal Hospital, Baselland
Cholelithiasis (Without Cholecystitis), Pain, Postoperative
Video-assisted Umbilical Fascial Closure in Laparoscopic Cholecystectomy
A prospective randomized study was performed including consecutive patients who underwent an elective laparoscopic cholecystectomy (LC) for symptomatic cholelithiasis during the 18 months period.
- Conditions
- Cholelithiasis (Without Cholecystitis), Pain, Postoperative, Hernia Incisional
- Trial name
- NCT05208385
- Testing
- video-assisted umbilical closure
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Samsun Education and Research Hospital
Colorectal Neoplasms, Colorectal Surgery
Intraoperative Hyperspectral Imaging for Laparoscopic Surgery
The study aims to evaluate the use of the HyperSnap Surgical System (HSS1) during laparoscopic surgeries, specifically in bowel resections and cholecystectomies.
- Conditions
- Colorectal Neoplasms, Colorectal Surgery, Cholecystitis, Cholecystectomy, Laparoscopic
- Trial name
- LapHSI (NCT06700317)
- Testing
- HSS1
- Volunteers
- 40 people
- Sponsor
- King's College London
Cholecystitis, Pain
The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy
The goal of this randomized double blind study is to compare the effects of hyoscine-n-butylbromide, and ondansetron on postoperative nausea-vomiting, and pain in patients who underwent laparoscopic cholecystectomy.The main…
- Conditions
- Cholecystitis, Pain, Nausea
- Trial name
- NCT06927817
- Testing
- hyoscine-n-butylbromide, ondansetron, • hyoscine-n-butylbromide • ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Neuromuscular Blocking Agents, Reversal of Neuromuscular Blockade
Recovery Times of Half Dose Sugammadex and Neostigmine for Rocuronium-induced Neuromuscular Blockade
In operating procedure with general anesthesia muscle relaxant is usually used to increase success rate of the operation and to give better outcome.
- Conditions
- Neuromuscular Blocking Agents, Reversal of Neuromuscular Blockade, Recovery Time
- Trial name
- NCT06794450
- Testing
- Sugammadex 1 mg/kg, Neostigmine + Atropine
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Padjadjaran
Postoperative Pain, Acute
Effectiveness of Fentanyl-Added TAP Block in Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effectiveness of adding fentanyl to the TAP block in laparoscopic cholecystectomy cases.
- Trial name
- NCT06778668
- Testing
- TAP block with bupivacaine only, TAP block with bupivacaine and fentanyl
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uludag University
Benign Gallbladder Disease
Single-Incision Laparoscopic Cholecystectomy with Inflexible Laparoscopic Instruments and Laparoscopy: a Single-Center Experience
Since being introduced by Mühe in 1985, laparoscopic cholecystectomy (LC) has garnered global acceptance and defined as gold standard treatment for benign gallbladder diseases (BGDs).
- Trial name
- NCT06708390
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain, Postoperative
Duloxetine for Postoperative Pain of Laparoscopic Cholecystectomy
Recent studies on the impact of perioperative duloxetine for treatment of acute postoperative pain have yielded positive outcomes with respect to reduction opioid consumption.
- Trial name
- NCT05115123
- Testing
- Duloxetine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Laparoscopic Cholecystectomy
Responses to Colloid Infusions
In situations such as dehydration, illness and surgery, fluid 'drips' are given to patients to keep them hydrated. Different fluids stay in the circulation for different lengths of time.
- Trial name
- NCT00868062
- Testing
- Succinylated gelatine, 40g/L, (Gelofusine - B Braun)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham